
NCBI . NLM . NIH . GOV {
}
Title[redir]:
BsmI (rs1544410) and FokI (rs2228570) vitamin D receptor polymorphisms, smoking, and body mass index as risk factors of cutaneous malignant melanoma in northeast Italy - PMC
Description:
: To investigate whether vitamin D receptor gene (VDR) BsmI-rs1544410 and FokI-rs2228570 polymorphisms, smoking duration, and body mass index (BMI) are risk factors for cutaneous melanoma, especially metastatic melanoma. : We studied 120 cutaneous ...
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Keywords {🔍}
melanoma, patients, doi, smoking, metm, years, controls, healthy, nmetm, pubmed, google, scholar, risk, vdr, study, obesity, vitamin, cancer, bbbb, adjusted, allele, pmc, polymorphisms, combined, receptor, bmi, article, genotype, free, cutaneous, cases, ffff, studies, factors, confounders, kgm, genetic, association, significant, showed, observed, malignant, age, effects, vdrbsmi, increased, gene, analysis, variables, combination,
Topics {✒️}
long-lasting variations induced genome-wide dna methylation pmc beta search affecting fair-skinned individuals1-3 dissect clinically-significant relationships friuli-venezia giulia uk case-control comparisons poor melanoma-specific survival10 suggest gene-environment effects future large-scale studies influence vdr-mrna expression italian case-control study smoking-related increased risks10 vitamin d-activated vdr 25-hydroxyvitamin d2/d3 levels sun-reactive skin types clinical/histological/radiological findings recent meta-analysis22 reported vdr single-nucleotide polymorphisms obesity-related genetic variants explored vdr bsmi-rs1544410 biological pathways related vdr-foki genotype ff foki-rs2228570 snps separately publisher site pdf melanoma cell lines license information pmcid vdr-bsmi bb genotype case-control design case-control investigations16 major primary tumor increasing evidence showed detailed reported information foki restriction sites van meurs jbj van leeuwen jpm cancer biol med bsmi restriction enzyme case-case study multiple primary melanoma vdr activities induced united states government southern european countries3 pathophysiological pathways underlying chromosome 12q12-q14 written informed consent austro-hungarian territory clark-grade invasion tumor-infiltrating lymphocytes hardy-weinberg equilibrium
Questions {❓}
- Available at: ecoiarcfr/eucan/Canceraspx?
- International trends in the incidence of malignant melanoma 1953-2008-are recent generations at higher or lower risk?
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