
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals - PMC
Description:
Mitochondrial stress activates a concerted mitonuclear response to safeguard and repair mitochondrial function. Quirós et al. assessed the transcriptome, proteome, and metabolome of mammalian cells under four types of stressors and combine ...
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Keywords {🔍}
mitochondrial, stress, atf, fig, analysis, doi, pubmed, google, scholar, genes, cells, pmc, response, cell, article, free, expression, proteins, protein, data, levels, pathway, function, activation, cellular, metabolism, rna, conditions, enrichment, gene, pathways, metabolites, sequencing, mouse, control, uprmt, hela, table, stressors, activated, translation, treatment, common, performed, actinonin, observed, human, nature, upregulated, tissues,
Topics {✒️}
tandem mass tag 100 µm suc-leu-leu-val-tyr-amc adding ice-cold acetonitrile/methanol/water oxygen consumption rate extracellular acidification rate ionophore carbonyl cyanide-4 ethidium bromide quantitative trait locus mouse embryonic fibroblasts mrp levels false discovery rate crispr-cas-9–mediated genome editing synchronous-precursor-selection ms3 scan tmt tag quantitative rt-pcr analyses synchronous-precursor-selection ms3 precursors quantitative rt-pcr reactions kyoto encyclopedia unfolded protein response high-energy collision–induced dissociation pmc beta search agilent technologies bioanalyzer goat anti–rabbit hrp mouse anti–β-actin mitochondrial ribosomal proteins classical uprer marker mouse protein phosphorylation pmc copyright notice acetonitrile [acn] fast gapped-read alignment redox-regulated protein translocation oxidized glutathione activating mitochondrial biogenesis gsh/cysteine-gsh disulfide ratio trna-leu primers quadrupole ion-trap analysis cysteine glutathione disulfide box-whisker plots representing mitochondrial dna high-resolution mass spectra pooled tmt-labeled peptides co2-free incubator electron transport chain oxidative phosphorylation �oxidative phosphorylation” final protein-level fdr total ros levels heme-regulated eif2alpha kinase amino acid–related pathways �aminoacyl−trna biosynthesis”
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- Find out how much https://doi.org/10.1111/j.1432-1033.1996.0098h.x earns monthly
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