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Keywords {🔍}

expression, gpcrs, cells, gpcr, fig, cell, gpr, mice, data, smc, doi, analysis, pubmed, google, scholar, smao, singlecell, supplementary, individual, receptors, genes, vascular, pmc, expressed, gene, article, types, free, muscle, healthy, showed, receptor, inflammatory, number, rtpcr, rna, activation, smsk, cluster, cxcr, repertoire, dedifferentiating, gprcb, control, myh, ecbr, heat, shown, atherosclerotic, smooth,

Topics {✒️}

ve-cadherin-cre-recombinase transgenic mouse western-style high-fat diet25 g12-g13-larg-mediated signaling single-cell rt-pcr analysis g-protein-coupled receptor signaling intron-spanning primer design single-cell rt-pcr high-throughput quantitative pcr fpr1/fpr2/ccr1/c5ar1-expressing cells chicken anti-ß-galactosidase reference genes β-actin protein-coupled receptor repertoires goat anti-chicken igg platelet-derived growth factor single-cell mrna sequencing protein-coupled receptor signaling pmc beta search raralpha-dependent signaling pathway single-cell gpcr repertoires k-means clustering results fitc-labelled antibodies directed apc-labelled antibodies directed k-means clustering identified gpcr-based therapies encompasses g-protein-coupled receptors g-protein coupled receptors cell cycle-dependent manner protein-coupled receptor expression region-specific antiproliferative effect k-means clustering data single-cell expression analysis rt-pcr expression data single-cell amplificates obtained col3a1– cytokines/growth factors protein-coupled receptor repertoire single-cell gpcr expression calcitonin gene-related peptide g12/13-coupled receptors encoded single-cell cdnas negative exert anti-proliferative effects rare cell populations intron-spanning design gpcr-based therapeutic strategies dtom/egfp-reporterpos mice resulting single-cell suspensions express β-galactosidase pooled cell rna/cdna smooth muscle proliferation high-fat diet showed t-sne map representation

Questions {❓}

• GPCR expression in tissues and cells: are the optimal receptors being used as drug targets?

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