
NCBI . NLM . NIH . GOV {
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Title[redir]:
Autoantibody to MOG suggests two distinct clinical subtypes of NMOSD - PMC
Description:
We characterized a unique group of patients with neuromyelitis optica spectrum disorder (NMOSD) who carried autoantibodies of aquaporin-4 (AQP4) and myelin-oligodendrocyte glycoprotein (MOG). Among the 125 NMOSD patients, 10 (8.0%) were AQP4- and ...
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Keywords {🔍}
patients, doi, lesions, mogab, nmosd, aqpab, doublepositive, positive, pubmed, google, scholar, brain, mog, antibodies, lesion, disease, figure, nmo, group, nerve, mogabpositive, optica, mri, pmc, clinical, neuromyelitis, cord, aqp, spinal, antibody, aqpabpositive, mslike, study, visual, article, kitley, patient, retinal, optic, groups, free, features, tanaka, detection, edss, disability, fiber, layer, enhancement, acuity,
Topics {✒️}
t2-weighted hyper-intensities evident facs-based cell-binding assays fluorescence-activated cell sorting full-length mog-assay mog-ab-positive nmosd individuals mog-ab-positive patients presented full-length mog-ab express aqp4 m23-egfp mog-ab double-positive patients pmc beta search aqp4-ab-double positive patients aqp4-ab-positive patients suggested mog-egfp/293t cells aqp4-egfp/ 293t cells mog-specific immune responses mog-ires-dsred cassette myelin oligodendrocyte glycoprotein-specific mog-igg binding index mog-ab single positive aqp4-ab single positive rabbit anti-human aqp4 myelin-oligodendrocyte glycoprotein antibodies mog-ab assays relative distinguish aqp4-ab-positive peri-papillary tissue measured mog-ab dual positivity retinal nerve fiber longitudinally extensive myelitis aqp4-ab-positivepatient group t2-weighted hyperintensities hyperintense t2 lesions post-testing recovery period mog-ab-positive group mog-ab double positive aqp4-ab-positive group aqp4-ab negative patients neuromyelitis optica mog-igg aqp4-ab patients argues mog-ab titers relative optical coherence tomography intact blood-brain-barrier intact blood-brain barrier mog-ab-positive patients aqp4-ab-positive patients 26 aqp4-ab-positive patients 23 aqp4-ab-positive patients egfp/293t cells egfp positive cells team transfected mog myelin-oligodendrocyte glycoprotein
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