
NCBI . NLM . NIH . GOV {
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Title[redir]:
Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and Treatment - PMC
Description:
Hu-antigen R (HuR) is an RNA-binding posttranscriptional regulator that belongs to the Hu/ELAV family. HuR expression levels are modulated by a variety of proteins, microRNAs, chemical compounds, or the microenvironment, and in turn, HuR affects ...
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Keywords {🔍}
hur, doi, cells, protein, mrna, cancer, pubmed, google, scholar, expression, cell, breast, levels, mcf, pmc, mdamb, article, free, mcfa, kinase, factor, tumor, growth, binding, target, regulation, receptor, binds, sirnamediated, silencing, genes, rna, biol, rnabinding, translation, utr, stabilization, stability, cytoplasmic, mol, lines, patients, role, carcinoma, cycle, overexpression, res, mrnas, proliferation, increases,
Topics {✒️}
serine/threonine-protein kinase chk2 cold-inducible rna-binding protein ras-related protein rab-2a sirna-mediated brca1-iris silencing au-rich waf1-hud sequence g2/mitotic-specific cyclin-b1 full-length cyclin e1 il1-beta–stimulated hs578t cells hur–hox-a5 mrna interaction c-fms proto-oncogene expression proto-oncogene c-fms expression autoimmune rna-binding protein sirna-mediated hur silencing mda-mb-231 hur-overexpressing cells domain-specific phosphomimetic mutation macrophage beta2 integrin-mediated nonreceptor tyrosine-protein kinase rna-binding protein predicts low–molecular weight isoforms rna-binding factor hur sirna-mediated cirbp silencing tyrosine-protein kinase jak3 platelet-derived growth factor rna-binding protein hur pmc beta search homeobox protein hox-a5 low-molecular-weight inhibitors cyclic gmp-elevating agents site-directed mutagenesis confirmed mrna exon-intron splicing wnt-5a protein levels suppresses wnt-5a translation adenine/uridine-rich elements high-throughput screening methods hypoxia-inducible factor 1alpha rna-binding posttranscriptional regulator hur-overexpressing tumors appeared proto-oncogene c-fms er-targeted endocrine therapies wnt-5a mrna translation short-wavelength ultraviolet light undergoes caspase-mediated cleavage anthracycline-based neoadjuvant chemotherapy brca1-iris increases total [70] proto-oncogenes c-fos proto-oncogenes c-fos sirna-mediated silencing brca1-iris overexpression revealed auuua-mediated mrna decay hur-mediated differential regulation
Questions {❓}
- Why is Hu where?
- Tyrosine protein kinase Yes (YES1) Expression⁎ (?
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- See how much https://scholar.google.com/scholar_lookup?journal=J%20Pharmacol%20Exp%20Ther&title=Loss%20of%20protein%20kinase%20Cdelta/HuR%20interaction%20is%20necessary%20to%20doxorubicin%20resistance%20in%20breast%20cancer%20cell%20lines&author=E.%20Latorre&author=I.%20Castiglioni&author=P.%20Gatto&author=S.%20Carelli&author=A.%20Quattrone&volume=349&publication_year=2014&pages=99-106&pmid=24492650&doi=10.1124/jpet.113.211839& makes per month
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