
NCBI . NLM . NIH . GOV {
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Title[redir]:
Genome wide copy number analysis of single cells - PMC
Description:
Copy number variation (CNV) is increasingly recognized as an important contributor to phenotypic variation in health and disease. Most methods for determining CNV rely on admixtures of cells, where information regarding genetic heterogeneity is ...
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Keywords {π}
dna, number, single, genome, cell, copy, data, doi, sequencing, supplementary, sample, cat, cells, samples, buffer, profiles, wga, purification, library, reads, file, analysis, flow, pubmed, google, scholar, methods, nuclei, step, minutes, plate, pcr, figure, provided, mix, amplification, beads, cancer, steps, sequence, pmc, tissue, tumor, bins, article, sns, nature, open, genomic, libraries,
Topics {βοΈ}
s1-s2-s3-s4 refers polystyrene round-bottom tube childhood myelodysplastic syndromes--challenge somatic copy-number alteration gov/traces/sra/sra pmc beta search human olfactory receptors primer extension pre-amplification genome amplifications kit-wga4 differing copy number degenerate oligonucleotide primers/adaptors cmd batch /filepath/srr054616 fine-point disposable scalpels paired-end sequencing data dna cell-cycle analysis sequence-ready dna libraries single nucleotide resolution input-program-output labels experimental design section 3-quals hg19 /filepath/sequence transfer covaris micro-tubes primary tumor mass copy number landscapes somatic mutations identified sonicator covaris e210 copy number variation cell line material laser-capture-microdissection publisher site pdf high-resolution mapping sequence alignment/map format ampure bead purification infer copy number guide therapeutic decisions copy number determination competing financial interests copy number profiles truseq indexing system focus acoustics system 16/samtools index /filepath/srr054616 copy number profile copy number analysis adaptor- βadaptor βlinkers single cell profiles comparable cell sorter copy number alterations copy number estimates estimated copy number copy number estimation copy-number alterations
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