
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration - PMC
Description:
A recent comprehensive whole genome analysis of a large breast cancer cohort was used to link known and novel drivers and substitution signatures to the transcriptome of 266 cases. Here, we validate that subtype-specific aberrations show concordant ...
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Keywords {🔍}
cancer, signature, cases, expression, breast, substitutions, signatures, doi, number, genes, pubmed, google, scholar, data, mutations, supplementary, pmc, mutational, article, gene, fig, samples, free, cell, til, high, cohort, substitution, test, patients, higher, top, erpositive, analysis, type, group, infiltrate, amino, mcc, acid, ccnd, numbers, driver, mwu, gse, total, cycle, mutated, found, results,
Topics {✒️}
chek21100delc-mutated breast carcinomas eu-fp7-ddr response project survival kaplan−meier curves kaplan–meier survival curves serena nik-zainal 4 metastasis-free survival data relapse-free survival data european-genome phenome archive pmc beta search anne-lise børresen-dale 31 metastasis-free survival ihc-scored her2-positivity relapse-free survival mann–whitney u-test x-axis shows time 625 lymph-node negative genome-wide expression patterns cd8 t-cell epitopes wild-type amino acid soft-red coloured bar r-package ‘global test'39 mitotic cell cycle tumour-infiltrating lymphocytes license information pmcid rank er-positive samples amino acid properties primary breast cancer significantly higher expressed primary breast cancer9 til specific rna-signature empirical bayes methods er-negative light grey human breast tumors breast cancers exhibit breast tumour cell relapse-free similar expression levels showed higher numbers er-positive dark grey mutated amino acid additional information immune cell infiltration cell cycle phenotype gene expression omnibus t-cell epitopes high til/low mcc low til/high mcc t-cell response publisher site pdf showed increased numbers
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- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi