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Keywords {🔍}

tumor, pericytes, tumors, doi, cells, pdgfbb, cell, fig, fsp, pubmed, google, scholar, cancer, stromal, human, group, fibroblasts, expression, mice, pericyte, metastasis, growth, pft, vessels, red, fields, αsma, antibody, scale, pdgfbbstimulated, signals, pmc, mouse, primary, bar, article, signaling, quantification, data, green, vascular, cafs, free, invasion, findings, tissues, patients, tpdgfbb, treatment, significantly,

Topics {✒️}

anti-pdgfrα–treated t241-pdgf-bb tumors cy5-labeled goat anti-rabbit imatinib-treated t24-pdgf-bb tumors scrambled-shrna–transfected sc-a431 tumors buffer-treated t241-pdgf-bb tumors imatinib-treated t241-pdgf-bb tumors benjamini–hochberg false-discovery rate pdgf-bb–stimulated pericytes possessed coimplanted egfp-t241 tumors human pdgf-bb–producing tumors pdgf-bb–stimulated pericytes changed tumor-derived pdgf-bb contributes pdgf-bb–stimulated pericytes compared mediate pdgf-bb–recruited cafs tumor cell-derived pdgf-bb pdgf-bb-pericyte tumors compared goat anti-rabbit cy3 pdgfb-shrna–transfected sc-a431tumors t241-vector-egfp tumors allowed nonstimulated pericyte-t241-vector cell t241-pdgf-bb tumors grown pdgf-bb-pdgfrβ signaling pathway pdgf-bb–stimulated pericytes play rabbit anti-egfp antibody pdgf-bb–positive tumors compared independent pdgf-bb–expressing tumor pdgf-bb–expressing tumors suggested pdgf-bb–mediated pericyte association pdgf-bb-pdgfrβ–induced pft t241-pdgf-bb-egfp platelet-derived growth factors pdgf-bb–induced pft occurs pdgf-bb–promoted cancer invasion rabbit anti-cleaved caspase-3 rabbit polyclonal anti-ng2 acid-stimulated mitogenic activity tumor-derived pdgf-bb rat anti-endomucin antibody rabbit anti-ng2 antibody pmc beta search protease-activated growth factor pdgf-bb–expressing t241 genome-wide array analysis t241-pdgf-bb tumors pdgf-bb–stimulated pericytes pdgf-bb tumors compared genome-wide expression analysis tamoxifen-induced ap-tdtomato-red pdgf-bb–stimulated pft species-matching secondary antibody

Questions {❓}

• Angiogenesis: An organizing principle for drug discovery?
• Could it be possible that other host cells in tumors differentiate into CAFs under the influence of specific signaling systems?
• Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: Are angiomyolipomas neoplasms of stem cells?
• How is this multicellular process modulated in the tumor microenvironment?
• Would high numbers of pericytes be advantageous for tumor growth and metastasis?

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