
NCBI . NLM . NIH . GOV {
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Title[redir]:
The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells - PMC
Description:
Self-renewing, chemoresistant breast cancer stem cells are believed to contribute significantly to cancer invasion, migration and patient relapse. Therefore, the identification of signaling pathways that regulate the acquisition of stem-like ...
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Keywords {🔍}
cells, ahr, doi, cancer, cell, stem, aldhhigh, expression, breast, google, scholar, pubmed, aldhlow, fig, data, pmc, article, cypb, free, activity, sum, hst, tumor, levels, receptor, hydrocarbon, genes, aryl, ficz, significant, human, sox, significantly, aldh, gene, presented, treated, hours, migration, additional, experiments, mice, results, tumors, vehicletreated, formation, standard, lines, shown, normalized,
Topics {✒️}
compound 2-methyl-2h-pyrazole-3-carboxylic acid er−/pr−/her2− hs578t cells er−/pr−/her2− cells turborfp-shahr transduced cells due dox-inducible shahr-transduced hs578t microarray/rna-seq data compiled 2-methyl-4-o-tolylazo-phenyl 100 iu penicillin/100 μg/ml streptomycin dox-inducible shahr-transduced ahr/sox2-specific chip assays inducible ahr-specific shrna ahr agonist-induced increases pmc beta search cytochrome p4501-dependent clearance real-time rt-pcr rela nf-κb subunit endogenous tumour-promoting ligand hematopoietic stem/progenitor cells cd44+/cd24− cell staining sirna-mediated ahr knockdown tissue-specific embryonic development ahr ligand-induced aldh human ahr-specific antibody early-stage breast carcinoma bright-glo luciferase system anti-ahr antibody h-211 exogenous agonist-induced ahr vehicle-treated aldhlow cells ultra-low adherence conditions higher tumor-initiating capacity 26984638 abstract background aldhhigh cell-derived tumors twenty nod/scid mice vehicle-treated aldhhigh cells gene-specific dna methylation aryl hydrocarbon receptor tumor stage-specific differences primary ahr-specific antibody cmv-green control plasmid inflammatory breast cancer tumor volume ± standard error aromatic hydrocarbon receptor aldhlow cells ± standard error ahr hyper-activation accelerates mda-mb-453 cells female nod/scid recipients ficz-treated aldhlow cells female nod/scid mice ahr-mediated chemoresistance takes percent aldhhigh ± standard error
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- Earnings of https://doi.org/10.1016/j.canlet.2011.11.025
- https://scholar.google.com/scholar_lookup?journal=Cancer%20Lett&title=Activation%20of%20the%20aryl%20hydrocarbon%20receptor%20represses%20mammosphere%20formation%20in%20MCF-7%20cells&author=S%20Zhao&author=Y%20Kanno&author=M%20Nakayama&author=M%20Makimura&author=S%20Ohara&volume=317&issue=2&publication_year=2012&pages=192-198&pmid=22123295&doi=10.1016/j.canlet.2011.11.025&'s financial summary
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