
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis - PMC
Description:
Cancer-associated fibroblasts (CAFs) are believed to play an essential role in cancer initiation and development. However, little research has been undertaken to evaluate the role of CAFs in endometrial cancer (EC) progression. We aim to detect the ...
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Keywords {🔍}
cells, doi, expression, cafs, sdfα, cancer, tumor, pubmed, google, scholar, cell, fibroblasts, tissues, patients, nfs, cxcr, media, stromal, invasion, progression, pmc, endometrial, mmp, survival, axis, article, free, fig, proliferation, growth, human, hecb, primary, sdfcxcr, migration, factor, factors, role, protein, usa, cancerassociated, normal, amd, metastasis, negative, conditioned, sdf, antibody, tissue, tumors,
Topics {✒️}
phosphate-buffered saline alpha-smooth muscle actin stromal cell-derived factor-1alpha macrophage chemoattractant protein-1 atypical hyperplastic endometrium colony stimulating factor-1 anti-fibroblast-activating protein stromal cell-derived factor-1α hyperplastic endometrium smooth muscle cells migration inhibitory factor anti-fibroblast-specific protein streptavidin-peroxidase-biotin reagent kit blocking pi3k/akt/beta-catenin pathway normal endometrium sdf-1α-induced cell proliferation stromal derived factor-1 pro-invasive factor secretion matrix metalloproteinases lymphocyte chemoattractant sdf-1 sdf-1α protein concentration spindle-shaped mesenchymal cells inhibit sdf-1α-induced akt tumor-inhibitory role serum-free dmem/f12 anti-α-sma anti-pd-l1 immunotherapy rabbit anti-human akt paracrine tgf-beta signalling sdf-1α-induced migration activating pi3k/akt myocardial ischemia/reperfusion injury pmc beta search fibroblast-derived cxcl12 extracellular matrix gel fibroblast-derived gdf15 sdf-1α-induced proliferation caf-mediated cell proliferation cxcl12-cxcr4 chemokine pathway independent prognostic factor α-sma expression tumor-derived factors affect tgf-beta mediated mechanism cd26/dipeptidyl peptidase iv negative prognostic factor interleukin-1 sdf-1α expression emerged normal endometrial tissues sdf-1α/cxcr4 axis normal endometrial stroma
Questions {❓}
- Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids?
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