
NCBI . NLM . NIH . GOV {
}
Title[redir]:
The Androgen Receptor Bridges Stem Cell-Associated Signaling Nodes in Prostate Stem Cells - PMC
Description:
The therapeutic potential of stem cells relies on dissecting the complex signaling networks that are thought to regulate their pluripotency and self-renewal. Until recently, attention has focused almost exclusively on a small set of “core” ...
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Keywords {🔍}
doi, stem, cells, cell, pubmed, google, scholar, prostate, cancer, pmc, article, free, signaling, androgen, pluripotency, expression, selfrenewal, receptor, human, nature, differentiation, state, embryonic, stat, nanog, cscs, escs, role, journal, transcriptional, pluripotent, csc, basal, population, research, normal, studies, regulation, factors, epithelial, phenotype, oct, activity, maintenance, sox, pikakt, science, states, transcription, somatic,
Topics {✒️}
akt/gsk3/β-catenin signaling pathway tgfbeta/activin-mediated smad signaling aldh+/cd44+/α2β1+ csc population psa−/lo cells indicating htert-immortalized primary nonmalignant pharmacological gsk-3-specific inhibitor androgen receptor-repressed gene involves erk-mediated phosphorylation pmc beta search prostate cancer stem/progenitor ccl5/hif2α/androgen receptor signals pten-deficient prostate cancer jak2/stat3 signaling pathway cancer stem cells—perspectives cd44+cd24− stem cell human bone marrow stem cell-based therapy stimulates androgen receptor-mediated ligand-inducible transcription factor blocks stat3-mediated transcription pi3k/akt signaling cascade antagonistic fgf/erk signaling pi3k/akt signaling pathways triple-negative breast cancer gene expression signature pten/akt/pi3k signaling phosphoinositide 3-kinase-dependent signaling cd133-positive cscs reduces inhibits pi3k/akt signaling gsk3-mediated c-myc castration decreases thrombocytopoiesis mesenchymal stem cells complex signaling networks tumour-initiating stem akt-mediated gsk3 inhibition publisher site pdf phenotypically mixed tumor prostate epithelial lineages breast cancer progression ar negatively regulates basal cells adapt human prostate cancer cd44+/cd133+/α2β1+ esc lines yields erk signaling pathways akt/protein kinase erk1/2 prevents neural protein synthesis pathways malignant prostate tissue cell surface markers
Questions {❓}
- How do regulators of the stem cell gene expression program produce a self-renewing cell that remains poised for differentiation?
- How is pluripotency determined and maintained?
- How might cells integrate signals from their environment and choose whether to remain pluripotent or differentiate into progenitors?
- Prostate cancer stem cells: do they have a basal or luminal phenotype?
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- Learn how profitable https://scholar.google.com/scholar_lookup?journal=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America&title=Targeting%20the%20stromal%20androgen%20receptor%20in%20primary%20prostate%20tumors%20at%20earlier%20stages&author=Y.%20Niu&author=S.%20Altuwaijri&author=S.%20Yeh&volume=105&issue=34&publication_year=2008&pages=12188-12193&pmid=18723670&doi=10.1073/pnas.0804701105& is on a monthly basis
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- What's the monthly income of https://doi.org/10.1002/stem.1087?
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- What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Prostate&title=Enrichment%20of%20putative%20prostate%20cancer%20stem%20cells%20after%20androgen%20deprivation:%20upregulation%20of%20pluripotency%20transactivators%20concurs%20with%20resistance%20to%20androgen%20deprivation%20in%20LNCaP%20cell%20lines&author=D.%20Seiler&author=J.%20Zheng&author=G.%20Liu&volume=73&issue=13&publication_year=2013&pages=1378-1390&pmid=23728788&doi=10.1002/pros.22685&?
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- How much money does https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=The%20PSA%E2%88%92/lo%20prostate%20cancer%20cell%20population%20harbors%20self-renewing%20long-term%20tumor-propagating%20cells%20that%20resist%20castration&author=J.%20Qin&author=X.%20Liu&author=B.%20Laffin&volume=10&publication_year=2012&pages=556-569&pmid=22560078&doi=10.1016/j.stem.2012.03.009& generate?
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- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=Modern%20Pathology&title=Loss%20of%20androgen%20receptor%20expression%20predicts%20early%20recurrence%20in%20triple-negative%20and%20basal-like%20breast%20cancer&author=A.%20A.%20Thike&author=L.%20Y.-Z.%20Chong&author=P.%20Y.%20Cheok&volume=27&issue=3&publication_year=2014&pages=352-360&pmid=23929266&doi=10.1038/modpathol.2013.145&?
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- How much revenue does https://scholar.google.com/scholar_lookup?journal=STEM%20CELLS&title=STAT3%20is%20required%20for%20proliferation%20and%20maintenance%20of%20multipotency%20in%20glioblastoma%20stem%20cells&author=M.%20M.%20Sherry&author=A.%20Reeves&author=J.%20K.%20Wu&author=B.%20H.%20Cochran&volume=27&issue=10&publication_year=2009&pages=2383-2392&pmid=19658181&doi=10.1002/stem.185& produce monthly?
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- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=Module%20map%20of%20stem%20cell%20genes%20guides%20creation%20of%20epithelial%20cancer%20stem%20cells&author=D.%20J.%20Wong&author=H.%20Liu&author=T.%20W.%20Ridky&author=D.%20Cassarino&author=E.%20Segal&volume=2&issue=4&publication_year=2008&pages=333-344&pmid=18397753&doi=10.1016/j.stem.2008.02.009&
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- How much income is https://doi.org/10.1038/sj.onc.1207930 earning monthly?
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?journal=Oncogene&title=Self-renewal%20of%20teratocarcinoma%20and%20embryonic%20stem%20cells&author=I.%20Chambers&author=A.%20Smith&volume=23&issue=43&publication_year=2004&pages=7150-7160&pmid=15378075&doi=10.1038/sj.onc.1207930&?
- How much profit is https://doi.org/10.1242/dev.02787 making per month?
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- What is the monthly revenue of https://doi.org/10.1016/s0092-8674(03)00392-1?
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Cell&title=Functional%20expression%20cloning%20of%20Nanog,%20a%20pluripotency%20sustaining%20factor%20in%20embryonic%20stem%20cells&author=I.%20Chambers&author=D.%20Colby&author=M.%20Robertson&volume=113&issue=5&publication_year=2003&pages=643-655&pmid=12787505&doi=10.1016/s0092-8674(03)00392-1&
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- How profitable is https://scholar.google.com/scholar_lookup?journal=Cell&title=The%20homeoprotein%20nanog%20is%20required%20for%20maintenance%20of%20pluripotency%20in%20mouse%20epiblast%20and%20ES%20cells&author=K.%20Mitsui&author=Y.%20Tokuzawa&author=H.%20Itoh&volume=113&issue=5&publication_year=2003&pages=631-642&pmid=12787504&doi=10.1016/S0092-8674(03)00393-3&?
- How much money does https://doi.org/10.1038/74199 generate?
- How much does https://scholar.google.com/scholar_lookup?journal=Nature%20Genetics&title=Quantitative%20expression%20of%20Oct-3/4%20defines%20differentiation,%20dedifferentiation%20or%20self-renewal%20of%20ES%20cells&author=H.%20Niwa&author=J.-I.%20Miyazaki&author=A.%20G.%20Smith&volume=24&issue=4&publication_year=2000&pages=372-376&pmid=10742100&doi=10.1038/74199& make?
- How much revenue does https://doi.org/10.1038/ncb1589 generate?
- How much income is https://scholar.google.com/scholar_lookup?journal=Nature%20Cell%20Biology&title=Pluripotency%20governed%20by%20Sox2%20via%20regulation%20of%20Oct3/4%20expression%20in%20mouse%20embryonic%20stem%20cells&author=S.%20Masui&author=Y.%20Nakatake&author=Y.%20Toyooka&volume=9&issue=6&publication_year=2007&pages=625-635&pmid=17515932&doi=10.1038/ncb1589& earning monthly?
- What's the total monthly financial gain of https://doi.org/10.1016/j.cell.2006.07.024?
- Profit of https://scholar.google.com/scholar_lookup?journal=Cell&title=Induction%20of%20pluripotent%20stem%20cells%20from%20mouse%20embryonic%20and%20adult%20fibroblast%20cultures%20by%20defined%20factors&author=K.%20Takahashi&author=S.%20Yamanaka&volume=126&issue=4&publication_year=2006&pages=663-676&pmid=16904174&doi=10.1016/j.cell.2006.07.024&
- How much revenue does https://doi.org/10.1016/j.cell.2008.07.020 generate?
- Explore the financials of https://scholar.google.com/scholar_lookup?journal=Cell&title=Connecting%20microRNA%20genes%20to%20the%20core%20transcriptional%20regulatory%20circuitry%20of%20embryonic%20stem%20cells&author=A.%20Marson&author=S.%20S.%20Levine&author=M.%20F.%20Cole&volume=134&issue=3&publication_year=2008&pages=521-533&pmid=18692474&doi=10.1016/j.cell.2008.07.020&
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- What is the earnings of https://scholar.google.com/scholar_lookup?journal=Nature&title=Nanog%20safeguards%20pluripotency%20and%20mediates%20germline%20development&author=I.%20Chambers&author=J.%20Silva&author=D.%20Colby&volume=450&issue=7173&publication_year=2007&pages=1230-1234&pmid=18097409&doi=10.1038/nature06403&?
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- How much revenue does https://scholar.google.com/scholar_lookup?journal=PLoS%20ONE&title=Sox2%20is%20an%20androgen%20receptor-repressed%20gene%20that%20promotes%20castration-resistant%20prostate%20cancer&author=S.%20Kregel&author=K.%20J.%20Kiriluk&author=A.%20M.%20Rosen&volume=8&issue=1&publication_year=2013&pmid=23326489&doi=10.1371/journal.pone.0053701& generate?
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- Financial intake of https://scholar.google.com/scholar_lookup?journal=The%20Prostate&title=The%20pluripotency%20factor%20Nanog%20is%20directly%20upregulated%20by%20the%20androgen%20receptor%20in%20prostate%20cancer%20cells&author=S.%20Kregel&author=R.%20Z.%20Szmulewitz&author=D.%20J.%20V.%20Griend&volume=74&publication_year=2014&pages=1530-1543&pmid=25175748&doi=10.1002/pros.22870&
- https://doi.org/10.1002/stem.29's total income per month
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=STEM%20CELLS&title=Functional%20evidence%20that%20the%20self-renewal%20gene%20NANOG%20regulates%20human%20tumor%20development&author=C.%20R.%20Jeter&author=M.%20Badeaux&author=G.%20Choy&volume=27&issue=5&publication_year=2009&pages=993-1005&pmid=19415763&doi=10.1002/stem.29&?
- What's the revenue for https://doi.org/10.1038/onc.2011.114?
- How much profit does https://scholar.google.com/scholar_lookup?journal=Oncogene&title=NANOG%20promotes%20cancer%20stem%20cell%20characteristics%20and%20prostate%20cancer%20resistance%20to%20androgen%20deprivation&author=C.%20R.%20Jeter&author=B.%20Liu&author=X.%20Liu&volume=30&issue=36&publication_year=2011&pages=3833-3845&pmid=21499299&doi=10.1038/onc.2011.114& generate?
- How much profit does https://doi.org/10.1002/pros.20895 make?
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=The%20Prostate&title=Oct4A%20is%20expressed%20by%20a%20subpopulation%20of%20prostate%20neuroendocrine%20cells&author=P.%20Sotomayor&author=A.%20Godoy&author=G.%20J.%20Smith&author=W.%20J.%20Huss&volume=69&issue=4&publication_year=2009&pages=401-410&pmid=19058139&doi=10.1002/pros.20895&?
- What's the financial intake of https://doi.org/10.1002/pros.20934?
- What are the earnings of https://scholar.google.com/scholar_lookup?journal=Prostate&title=The%20expression%20of%20pluripotency%20marker%20oct%203/4%20in%20prostate%20cancer%20and%20benign%20prostate%20hyperplasia&author=N.%20Monsef&author=M.%20Soller&author=M.%20Isaksson&author=P.%20A.%20Abrahamsson&author=I.%20Panagopoulos&volume=69&issue=9&publication_year=2009&pages=909-916&pmid=19274762&doi=10.1002/pros.20934&?
- How much does https://scholar.google.com/scholar_lookup?journal=The%20Prostate,%20Supplement&title=Neuroendocrine%20cells%20in%20benign%20and%20malignant%20prostate%20tissue:%20morphogenesis,%20proliferation,%20and%20androgen%20receptor%20status&author=H.%20Bonkhoff&volume=8&publication_year=1998&pages=18-22&pmid=9690659& pull in monthly?
- Financial intake of https://doi.org/10.1073/pnas.96.11.6199
- What's https://scholar.google.com/scholar_lookup?journal=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America&title=PTEN%20modulates%20cell%20cycle%20progression%20and%20cell%20survival%20by%20regulating%20phosphatidylinositol%203,4,5,-trisphosphate%20and%20Akt/protein%20kinase%20B%20signaling%20pathway&author=H.%20Sun&author=R.%20Lesche&author=D.-M.%20Li&volume=96&issue=11&publication_year=1999&pages=6199-6204&pmid=10339565&doi=10.1073/pnas.96.11.6199&'s gross income?
- What's the income of https://doi.org/10.1038/nature04747?
- What's the revenue for https://scholar.google.com/scholar_lookup?journal=Nature&title=PTEN%20maintains%20haematopoietic%20stem%20cells%20and%20acts%20in%20lineage%20choice%20and%20leukaemia%20prevention&author=J.%20Zhang&author=J.%20C.%20Grindley&author=T.%20Yin&volume=441&issue=7092&publication_year=2006&pages=518-522&pmid=16633340&doi=10.1038/nature04747&?
- Find out how much https://doi.org/10.1634/stemcells.2006-0219 earns monthly
- What's the monthly income of https://scholar.google.com/scholar_lookup?journal=Stem%20Cells&title=Activin%20A%20efficiently%20specifies%20definitive%20endoderm%20from%20human%20embryonic%20stem%20cells%20only%20when%20phosphatidylinositol%203-kinase%20signaling%20is%20suppressed&author=A.%20B.%20McLean&author=K.%20A.%20D'Amour&author=K.%20L.%20Jones&volume=25&issue=1&publication_year=2007&pages=29-38&pmid=17204604&doi=10.1634/stemcells.2006-0219&?
- How much does https://doi.org/10.1038/nature06027 make?
- Get to know what's the income of https://scholar.google.com/scholar_lookup?journal=Nature&title=IGF%20and%20FGF%20cooperatively%20establish%20the%20regulatory%20stem%20cell%20niche%20of%20pluripotent%20human%20cells%20in%20vitro&author=S.%20C.%20Bendall&author=M.%20H.%20Stewart&author=P.%20Menendez&volume=448&issue=7157&publication_year=2007&pages=1015-1021&pmid=17625568&doi=10.1038/nature06027&
- Explore the financials of https://doi.org/10.1016/j.stem.2012.01.014
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=Signaling%20network%20crosstalk%20in%20human%20pluripotent%20cells:%20a%20Smad2/3-regulated%20switch%20that%20controls%20the%20balance%20between%20self-renewal%20and%20differentiation&author=A.%20M.%20Singh&author=D.%20Reynolds&author=T.%20Cliff&volume=10&issue=3&publication_year=2012&pages=312-326&pmid=22385658&doi=10.1016/j.stem.2012.01.014& bring in?
- Income figures for https://doi.org/10.1073/pnas.0810956106
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America&title=The%20role%20of%20PTEN/Akt/PI3K%20signaling%20in%20the%20maintenance%20and%20viability%20of%20prostate%20cancer%20stem-like%20cell%20populations&author=A.%20Dubrovska&author=S.%20Kim&author=R.%20J.%20Salamone&volume=106&issue=1&publication_year=2009&pages=268-273&pmid=19116269&doi=10.1073/pnas.0810956106&
- What's the total monthly financial gain of https://doi.org/10.1074/jbc.m114.607846?
- How much does https://scholar.google.com/scholar_lookup?journal=The%20Journal%20of%20Biological%20Chemistry&title=Crosstalking%20between%20androgen%20and%20PI3K/AKT%20signaling%20pathways%20in%20prostate%20cancer%20cells&author=S.%20H.%20Lee&author=D.%20Johnson&author=R.%20Luong&author=Z.%20Sun&volume=290&issue=5&publication_year=2015&pages=2759-2768&pmid=25527506&doi=10.1074/jbc.m114.607846& gross monthly?
- What's the monthly income of https://doi.org/10.1016/j.ccr.2011.04.008?
- How much does https://scholar.google.com/scholar_lookup?journal=Cancer%20Cell&title=Reciprocal%20feedback%20regulation%20of%20PI3K%20and%20androgen%20receptor%20signaling%20in%20PTEN-deficient%20prostate%20cancer&author=B.%20S.%20Carver&author=C.%20Chapinski&author=J.%20Wongvipat&volume=19&issue=5&publication_year=2011&pages=575-586&pmid=21575859&doi=10.1016/j.ccr.2011.04.008& net monthly?
- See how much https://doi.org/10.1038/nm979 makes per month
- See how much https://scholar.google.com/scholar_lookup?journal=Nature%20Medicine&title=Maintenance%20of%20pluripotency%20in%20human%20and%20mouse%20embryonic%20stem%20cells%20through%20activation%20of%20Wnt%20signaling%20by%20a%20pharmacological%20GSK-3-specific%20inhibitor&author=N.%20Sato&author=L.%20Meijer&author=L.%20Skaltsounis&author=P.%20Greengard&author=A.%20H.%20Brivanlou&volume=10&issue=1&publication_year=2004&pages=55-63&pmid=14702635&doi=10.1038/nm979& makes per month
- https://doi.org/10.1016/j.bbamcr.2013.01.007's total income per month
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Biochimica%20et%20Biophysica%20Acta&title=Suppression%20of%20androgen%20receptor%20enhances%20the%20self-renewal%20of%20mesenchymal%20stem%20cells%20through%20elevated%20expression%20of%20EGFR&author=C.-K.%20Huang&author=M.-Y.%20Tsai&author=J.%20Luo&author=H.-Y.%20Kang&author=S.%20O.%20Lee&volume=1833&issue=5&publication_year=2013&pages=1222-1234&pmid=23333872&doi=10.1016/j.bbamcr.2013.01.007&
- Financial intake of https://doi.org/10.1210/en.2008-0858
- What is the monthly revenue of https://scholar.google.com/scholar_lookup?journal=Endocrinology&title=Regulation%20of%20myogenic%20differentiation%20by%20androgens:%20cross%20talk%20between%20androgen%20receptor%CE%B2-catenin%20and%20follistatin/transforming%20growth%20factor-%CE%B2%20signaling%20pathways&author=R.%20Singh&author=S.%20Bhasin&author=M.%20Braga&volume=150&issue=3&publication_year=2009&pages=1259-1268&pmid=18948405&doi=10.1210/en.2008-0858&?
- How profitable is https://doi.org/10.1128/mcb.01405-08?
- What's the financial gain of https://scholar.google.com/scholar_lookup?journal=Molecular%20and%20Cellular%20Biology&title=Subcellular%20localization%20of%20glycogen%20synthase%20kinase%203beta%20controls%20embryonic%20stem%20cell%20self-renewal&author=M.%20Bechard&author=S.%20Dalton&volume=29&issue=8&publication_year=2009&pages=2092-2104&pmid=19223464&doi=10.1128/mcb.01405-08&?
- What's the financial gain of https://doi.org/10.1016/j.cell.2009.01.001?
- How much income is https://scholar.google.com/scholar_lookup?journal=Cell&title=Role%20of%20the%20murine%20reprogramming%20factors%20in%20the%20induction%20of%20pluripotency&author=R.%20Sridharan&author=J.%20Tchieu&author=M.%20J.%20Mason&volume=136&issue=2&publication_year=2009&pages=364-377&pmid=19167336&doi=10.1016/j.cell.2009.01.001& earning monthly?
- How much does https://doi.org/10.1242/dev.01670 net monthly?
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- How much cash flow does https://doi.org/10.1371/journal.pone.0003769 have monthly?
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- https://scholar.google.com/scholar_lookup?journal=Differentiation&title=myc%20maintains%20embryonic%20stem%20cell%20pluripotency%20and%20self-renewal&author=N.%20V.%20Varlakhanova&author=R.%20F.%20Cotterman&author=W.%20N.%20deVries&volume=80&issue=1&publication_year=2010&pages=9-19&pmid=20537458&doi=10.1016/j.diff.2010.05.001&'s financial summary
- Revenue of https://doi.org/10.1016/j.cell.2010.09.010
- What are the earnings of https://scholar.google.com/scholar_lookup?journal=Cell&title=A%20Myc%20network%20accounts%20for%20similarities%20between%20embryonic%20stem%20and%20cancer%20cell%20transcription%20programs&author=J.%20Kim&author=A.%20J.%20Woo&author=J.%20Chu&volume=143&issue=2&publication_year=2010&pages=313-324&pmid=20946988&doi=10.1016/j.cell.2010.09.010&?
- How much revenue does https://doi.org/10.1074/jbc.m610906200 produce monthly?
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- https://doi.org/10.1042/bst20051522's financial summary
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- How much does https://doi.org/10.1016/j.scr.2010.06.002 generate monthly?
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- What is the monthly revenue of https://doi.org/10.1016/j.celrep.2014.11.032?
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- What's the monthly income of https://doi.org/10.1038/39348?
- How much money does https://scholar.google.com/scholar_lookup?journal=Nature&title=Opposing%20BMP%20and%20EGF%20signalling%20pathways%20converge%20on%20the%20TGF-%CE%B2%20family%20mediator%20Smad1&author=M.%20Kretzschmar&author=J.%20Doody&author=J.%20Massagu%C3%A9&volume=389&issue=6651&publication_year=1997&pages=618-622&pmid=9335504&doi=10.1038/39348& generate?
- Get to know what's the income of https://doi.org/10.1016/j.stem.2008.07.001
- How much does https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=NANOG%20is%20a%20direct%20target%20of%20TGFbeta/activin-mediated%20SMAD%20signaling%20in%20human%20ESCs&author=R.-H.%20Xu&author=T.%20L.%20Sampsell-Barron&author=F.%20Gu&volume=3&issue=2&publication_year=2008&pages=196-206&pmid=18682241&doi=10.1016/j.stem.2008.07.001& bring in each month?
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- What's the total monthly financial gain of https://doi.org/10.1073/pnas.96.6.2846?
- How much money does https://scholar.google.com/scholar_lookup?journal=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America&title=Essential%20role%20of%20STAT3%20for%20embryonic%20stem%20cell%20pluripotency&author=R.%20Raz&author=C.-K.%20Lee&author=L.%20A.%20Cannizzaro&author=P.%20D'Eustachio&author=D.%20E.%20Levy&volume=96&issue=6&publication_year=1999&pages=2846-2851&pmid=10077599&doi=10.1073/pnas.96.6.2846& generate?
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- Learn how profitable https://scholar.google.com/scholar_lookup?journal=Genes%20and%20Development&title=Self-renewal%20of%20pluripotent%20embryonic%20stem%20cells%20is%20mediated%20via%20activation%20of%20STAT3&author=H.%20Niwa&author=T.%20Burdon&author=I.%20Chambers&author=A.%20Smith&volume=12&issue=13&publication_year=1998&pages=2048-2060&pmid=9649508&doi=10.1101/gad.12.13.2048& is on a monthly basis
- Income figures for https://doi.org/10.1172/jci44745
- https://scholar.google.com/scholar_lookup?journal=The%20Journal%20of%20Clinical%20Investigation&title=The%20JAK2/STAT3%20signaling%20pathway%20is%20required%20for%20growth%20of%20CD44+CD24%E2%88%92%20stem%20cell-like%20breast%20cancer%20cells%20in%20human%20tumors&author=L.%20L.%20C.%20Marotta&author=V.%20Almendro&author=A.%20Marusyk&volume=121&issue=7&publication_year=2011&pages=2723-2735&pmid=21633165&doi=10.1172/jci44745&'s financial summary
- How much revenue does https://doi.org/10.1038/ncomms8095 bring in?
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- How much revenue does https://doi.org/10.1126/science.8197455 bring in?
- Monthly income for https://scholar.google.com/scholar_lookup?journal=Science&title=Jak-STAT%20pathways%20and%20transcriptional%20activation%20in%20response%20to%20IFNs%20and%20other%20extracellular%20signaling%20proteins&author=J.%20E.%20Darnell&author=I.%20M.%20Kerr&author=G.%20R.%20Stark&volume=264&issue=5164&publication_year=1994&pages=1415-1421&pmid=8197455&doi=10.1126/science.8197455&
- What is the earnings of https://doi.org/10.1038/emboj.2013.177?
- What are the total earnings of https://scholar.google.com/scholar_lookup?journal=The%20EMBO%20Journal&title=Identification%20of%20the%20missing%20pluripotency%20mediator%20downstream%20of%20leukaemia%20inhibitory%20factor&author=G.%20Martello&author=P.%20Bertone&author=A.%20Smith&volume=32&issue=19&publication_year=2013&pages=2561-2574&pmid=23942233&doi=10.1038/emboj.2013.177&?
- How much does https://doi.org/10.1242/dev.030957 pull in monthly?
- What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Development&title=Klf4%20reverts%20developmentally%20programmed%20restriction%20of%20ground%20state%20pluripotency&author=G.%20Guo&author=J.%20Yang&author=J.%20Nichols&volume=136&issue=7&publication_year=2009&pages=1063-1069&pmid=19224983&doi=10.1242/dev.030957&?
- Revenue of https://doi.org/10.1016/j.cell.2008.02.039
- What's the income generated by https://scholar.google.com/scholar_lookup?journal=Cell&title=An%20extended%20transcriptional%20network%20for%20pluripotency%20of%20embryonic%20stem%20cells&author=J.%20Kim&author=J.%20Chu&author=X.%20Shen&author=J.%20Wang&author=S.%20H.%20Orkin&volume=132&issue=6&publication_year=2008&pages=1049-1061&pmid=18358816&doi=10.1016/j.cell.2008.02.039& each month?
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- https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=Stat3%20activation%20is%20limiting%20for%20reprogramming%20to%20ground%20state%20pluripotency&author=J.%20Yang&author=A.%20L.%20van%20Oosten&author=T.%20W.%20Theunissen&author=G.%20Guo&author=J.%20C.%20R.%20Silva&volume=7&issue=3&publication_year=2010&pages=319-328&pmid=20804969&doi=10.1016/j.stem.2010.06.022&'s financial summary
- What's https://doi.org/10.1038/ncomms1822's gross income?
- https://scholar.google.com/scholar_lookup?journal=Nature%20Communications&title=JAK/STAT3%20signalling%20is%20sufficient%20and%20dominant%20over%20antagonistic%20cues%20for%20the%20establishment%20of%20naive%20pluripotency&author=A.%20L.%20van%20Oosten&author=Y.%20Costa&author=A.%20Smith&author=J.%20C.%20R.%20Silva&volume=3,%20article%20817&publication_year=2012&pmid=22569365&doi=10.1038/ncomms1822&'s total income per month
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- What is the monthly revenue of https://doi.org/10.1002/stem.188?
- Financial intake of https://scholar.google.com/scholar_lookup?journal=STEM%20CELLS&title=Targeting%20interleukin%206%20signaling%20suppresses%20glioma%20stem%20cell%20survival%20and%20tumor%20growth&author=H.%20Wang&author=J.%20D.%20Lathia&author=Q.%20Wu&volume=27&issue=10&publication_year=2009&pages=2393-2404&pmid=19658188&doi=10.1002/stem.188&
- Get to know https://scholar.google.com/scholar_lookup?journal=American%20Journal%20of%20Translational%20Research&title=The%20roles%20of%20EZH2%20in%20cell%20lineage%20commitment&author=R.-H.%20Chou&author=Y.-L.%20Yu&author=M.-C.%20Hung&volume=3&issue=3&publication_year=2011&pages=243-250&pmid=21654879&'s earnings
- How much money does https://doi.org/10.1126/science.1227604 generate?
- Income figures for https://scholar.google.com/scholar_lookup?journal=Science&title=EZH2%20oncogenic%20activity%20in%20castration-resistant%20prostate%20cancer%20cells%20is%20plycomb-independent&author=K.%20Xu&author=Z.%20J.%20Wu&author=A.%20C.%20Groner&volume=338&issue=6113&publication_year=2012&pages=1465-1469&pmid=23239736&doi=10.1126/science.1227604&
- What's the monthly income of https://doi.org/10.1016/j.cell.2008.01.038?
- What's the revenue for https://scholar.google.com/scholar_lookup?journal=Cell&title=Stem%20cells%20and%20niches:%20mechanisms%20that%20promote%20stem%20cell%20maintenance%20throughout%20life&author=S.%20J.%20Morrison&author=A.%20C.%20Spradling&volume=132&issue=4&publication_year=2008&pages=598-611&pmid=18295578&doi=10.1016/j.cell.2008.01.038&?
- How much revenue does https://doi.org/10.1038/onc.2013.233 bring in?
- How much does https://scholar.google.com/scholar_lookup?journal=Oncogene&title=Infiltrating%20bone%20marrow%20mesenchymal%20stem%20cells%20increase%20prostate%20cancer%20stem%20cell%20population%20and%20metastatic%20ability%20via%20secreting%20cytokines%20to%20suppress%20androgen%20receptor%20signaling&author=J.%20Luo&author=S.%20Ok%20Lee&author=L.%20Liang&volume=33&issue=21&publication_year=2014&pages=2768-2778&pmid=23792449&doi=10.1038/onc.2013.233& generate monthly?
- Get to know what's the income of https://scholar.google.com/scholar_lookup?journal=Oncology%20Reports&title=Role%20of%20CCL5%20in%20invasion,%20proliferation%20and%20proportion%20of%20CD44+/CD24%E2%88%92%20phenotype%20of%20MCF-7%20cells%20and%20correlation%20of%20CCL5%20and%20CCR5%20expression%20with%20breast%20cancer%20progression&author=Y.%20Zhang&author=F.%20Yao&author=X.%20Yao&volume=21&issue=4&publication_year=2009&pages=1113-1121&pmid=19288016&
- What's the profit of https://doi.org/10.18632/oncotarget.4515?
- Explore the financials of https://scholar.google.com/scholar_lookup?journal=Oncotarget&title=Infiltrating%20bone%20marrow%20mesenchymal%20stem%20cells%20(BM-MSCs)%20increase%20prostate%20cancer%20cell%20invasion%20via%20altering%20the%20CCL5/HIF2%CE%B1/androgen%20receptor%20signals&author=J.%20Luo&author=S.%20O.%20Lee&author=C.%20Yun&author=R.%20Yang&author=C.%20Chang&volume=6&issue=29&publication_year=2015&pages=27555-27565&pmid=26342197&doi=10.18632/oncotarget.4515&
- How much does https://doi.org/10.1016/s0006-291x(03)00792-7 net monthly?
- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=Biochemical%20and%20Biophysical%20Research%20Communications&title=Interleukin-6%20differentially%20regulates%20androgen%20receptor%20transactivation%20via%20PI3K-Akt,%20STAT3,%20and%20MAPK,%20three%20distinct%20signal%20pathways%20in%20prostate%20cancer%20cells&author=L.%20Yang&author=L.%20Wang&author=H.-K.%20Lin&volume=305&issue=3&publication_year=2003&pages=462-469&pmid=12763015&doi=10.1016/s0006-291x(03)00792-7&
- What's https://doi.org/10.1016/j.scr.2013.07.010's gross income?
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Stem%20Cell%20Research&title=Endothelial%20cells%20provide%20a%20niche%20for%20placental%20hematopoietic%20stem/progenitor%20cell%20expansion%20through%20broad%20transcriptomic%20modification&author=C.%20M.%20Raynaud&author=J.%20M.%20Butler&author=N.%20M.%20Halabi&volume=11&issue=3&publication_year=2013&pages=1074-1090&pmid=23978474&doi=10.1016/j.scr.2013.07.010&
- How much revenue does https://doi.org/10.1126/science.1092436 produce monthly?
- Earnings of https://scholar.google.com/scholar_lookup?journal=Science&title=Defining%20the%20epithelial%20stem%20cell%20niche%20in%20skin&author=T.%20Tumbar&author=G.%20Guasch&author=V.%20Greco&volume=303&issue=5656&publication_year=2004&pages=359-363&pmid=14671312&doi=10.1126/science.1092436&
- How much income is https://doi.org/10.1038/nature06188 earning monthly?
- How much does https://scholar.google.com/scholar_lookup?journal=Nature&title=Mesenchymal%20stem%20cells%20within%20tumour%20stroma%20promote%20breast%20cancer%20metastasis&author=A.%20E.%20Karnoub&author=A.%20B.%20Dash&author=A.%20P.%20Vo&volume=449&issue=7162&publication_year=2007&pages=557-563&pmid=17914389&doi=10.1038/nature06188& generate monthly?
- What are the total earnings of https://doi.org/10.1159/000180295?
- How much does https://scholar.google.com/scholar_lookup?journal=Hormone%20Research&title=Stimulatory%20effects%20of%20androgens%20on%20normal%20children's%20bone%20marrow%20in%20culture:%20effects%20of%20BFU-E,%20CFU-E,%20and%20uroporphyrinogen%20I%20synthase%20activity&author=M.%20Claustres&author=C.%20Sultan&volume=23&issue=2&publication_year=1986&pages=91-98&pmid=3943773&doi=10.1159/000180295& generate monthly?
- What's the financial intake of https://doi.org/10.1002/1096-9896(0000)9999:9999<::AID-PATH803>3.0.CO;2-W?
- Explore the financials of https://scholar.google.com/scholar_lookup?journal=The%20Journal%20of%20Pathology&title=Localization%20of%20androgen%20receptor%20expression%20in%20human%20bone%20marrow&author=A.%20Mantalaris&author=N.%20Panoskaltsis&author=Y.%20Sakai&volume=193&issue=3&publication_year=2001&pages=361-366&pmid=11241417&doi=10.1002/1096-9896(0000)9999:9999<::AID-PATH803>3.0.CO;2-W&
- How much revenue does https://scholar.google.com/scholar_lookup?journal=The%20Journal%20of%20Laboratory%20and%20Clinical%20Medicine&title=Castration%20decreases%20thrombocytopoiesis%20and%20testosterone%20restores%20platelet%20production%20in%20castrated%20BALB/c%20mice:%20evidence%20that%20testosterone%20acts%20on%20a%20bipotential%20hematopoietic%20precursor%20cell&author=P.%20S.%20Sullivan&author=C.%20W.%20Jackson&author=T.%20P.%20McDonald&volume=125&issue=3&publication_year=1995&pages=326-333&pmid=7897299& bring in?
- What is the monthly revenue of https://doi.org/10.1084/jem.20082521?
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- Learn about the earnings of https://doi.org/10.1016/j.scr.2013.06.001
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Stem%20Cell%20Research&title=Loss%20of%20androgen%20receptor%20promotes%20adipogenesis%20but%20suppresses%20osteogenesis%20in%20bone%20marrow%20stromal%20cells&author=C.-K.%20Huang&author=K.-P.%20Lai&author=J.%20Luo&volume=11&issue=2&publication_year=2013&pages=938-950&pmid=23859805&doi=10.1016/j.scr.2013.06.001& bring in?
- Financial intake of https://doi.org/10.1002/hep.26135
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- How much does https://doi.org/10.1210/en.2005-0448 pull in?
- https://scholar.google.com/scholar_lookup?journal=Endocrinology&title=Tetrahydrogestrinone%20is%20an%20androgenic%20steroid%20that%20stimulates%20androgen%20receptor-mediated,%20myogenic%20differentiation%20in%20C3H10T1/2%20multipotent%20mesenchymal%20cells%20and%20promotes%20muscle%20accretion%20in%20orchidectomized%20male%20rats&author=R.%20Jasuja&author=D.%20H.%20Catlin&author=A.%20Miller&volume=146&issue=10&publication_year=2005&pages=4472-4478&pmid=15976054&doi=10.1210/en.2005-0448&'s revenue stream
- What's the income of https://doi.org/10.1002/jcb.23098?
- Revenue of https://scholar.google.com/scholar_lookup?journal=Journal%20of%20Cellular%20Biochemistry&title=Body%20composition%20changes%20and%20inhibition%20of%20fat%20development%20in%20vivo%20implicates%20androgen%20in%20regulation%20of%20stem%20cell%20lineage%20allocation&author=A.%20A.%20Semirale&author=X.-W.%20Zhang&author=K.%20M.%20Wiren&volume=112&issue=7&publication_year=2011&pages=1773-1786&pmid=21381083&doi=10.1002/jcb.23098&
- How much cash flow does https://doi.org/10.1111/j.1460-9568.2005.03942.x have monthly?
- How much does https://scholar.google.com/scholar_lookup?journal=The%20European%20Journal%20of%20Neuroscience&title=19-Nortestosterone%20influences%20neural%20stem%20cell%20proliferation%20and%20neurogenesis%20in%20the%20rat%20brain&author=K.%20Br%C3%A4nnvall&author=N.%20Bogdanovic&author=L.%20Korhonen&author=D.%20Lindholm&volume=21&issue=4&publication_year=2005&pages=871-878&pmid=15787693&doi=10.1111/j.1460-9568.2005.03942.x& pull in?
- What's https://github.com/ncbi's gross income?
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- Income figures for https://www.nlm.nih.gov/web_policies.html
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Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
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CDN Services {📦}
- Ncbi