
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Mediator Kinase Inhibition Further Activates Super-Enhancer Associated Genes in AML - PMC
Description:
Super-enhancers (SEs), which are composed of large clusters of enhancers densely loaded with the Mediator complex, transcription factors (TFs), and chromatin regulators, drive high expression of genes implicated in cell identity and disease, such as ...
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Keywords {🔍}
cdk, doi, cells, data, genes, cell, fig, google, scholar, molm, extended, performed, pubmed, pmc, treatment, expression, article, seassociated, mice, kinase, experiments, free, chipseq, shown, regions, supplementary, activity, gene, rna, aml, med, signal, replicates, analysis, experiment, lines, ibet, set, sem, brd, figure, biological, ses, red, pol, stat, day, days, growth, table,
Topics {✒️}
regulator vector plvx-ef1a-tet3g a300-793a lot a300-793a-2 a301-985a lot a301-985a50-3 tgf-β-stimulated smad2 t220 a302-500a lot a302-500a-1 inducible system plvx-tre3g-mcherry immuno-assisted activity-based profiling ca/cdk8/ccnc ternary complex anti-phospho-smad2/3 t220/t179 c5–c9 ethano bridge c-terminal extension helix pseudo-replicate pooled-consistency analysis cdk8/cycc/ca data collection anti-cdk8 bethyl a302-500a stat1 s727 phosphorylation sc-899x lot b2713 anti-cdk8 bethyl a302-501a plvx-ef1alpha-ires-mcherry plvx-ef1alpha-ires-zsgreen raw chip-seq data chip-seq density maps female nod-scid-il2rcγnull ca-cdk8-ccnc crystal structure chip-seq binding profiles anti-phospho-stat1 tyr701 anti-phospho-stat1 ser727 library-type fr-firstrand /site/anshulkundaje/projects/idr dose-dependently inhibits capture gst-pol ii-ctd miame-compliant microarray data pmc beta search cdk8 chip-seq data spp cross-correlation analysis apparent cation-π interaction chip-seq experiment yielded cdk8/cycc implicates specificity regulates β-catenin activity putative cation-π interaction total chip-seq signal hif1a employs cdk8-mediator genome-wide molecular signature build version ncbi37/hg19 kaplan-meier survival analysis 2 ng/ml gm-csf independent chip-seq experiments benjamini-hochberg38 adjusted p set-2 rna-seq acquisition med1 chip-seq data stat1 s727 substrate
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