
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Comprehensive molecular portraits of invasive lobular breast cancer - PMC
Description:
Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, 490 ductal (IDC), and 88 mixed IDC/ILC. Besides E-cadherin loss, the ...
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Keywords {๐}
ilc, doi, cancer, foxa, breast, mutations, tumors, google, scholar, idc, pubmed, figure, expression, pmc, dna, article, free, cdh, cases, mixed, protein, lobular, luma, levels, methylation, invasive, identified, molecular, akt, tumor, table, research, ecadherin, alterations, clinical, loss, features, binding, journal, increased, subtypes, genome, pten, mrna, data, analyses, signaling, ilclike, samples, genes,
Topics {โ๏ธ}
beta-catenin-egr1-mediated pten expression tp73 tcf/beta-catenin pkc pi3k/akt targets phospho-pras40 supplemental experimental procedures pmc beta search gabriella giorgi-cavaglieri foundation pi3k/akt pathway-specific protein pan-cancer proteomic perspective org/cancergenomics/tcga/brca_tcga germline e-cadherin gene reverse-phase protein array [google scholar] cadherin-catenin complex dissociation fork-head dna binding residue-residue minimum distances c-terminus transactivation domains c-terminus trans-activation relapsed classic e-cadherin identify dna hyper-methylation rna-seq read counts identified e-cadherin alterations ross-innes cs e-cadherin mrna expression lower ras-mapk signature mixed ductal/lobular carcinoma foxa3 fork-head domain pi3k/akt protein signature prognostic b-cell signatures supplementary materials included patient-specific pathway activities suppressing pi3k/akt signaling identified increased phospho-p27 phospho-protein expression signature low e-cadherin mrna phosphoinositide 3-kinase/akt pathway mrna-seq expression data coordinated mirna-seq analyses stat3-mediated akt activation estrogen receptor function coordinated rna-seq analyses advanced prostate cancer immune-related signatures determined cellโcell adhesion protein/phospho-protein level multiple cancer types phospho-protein expression differences lung cancer cells luminal/er+ breast cancers neoplastic cells implicates shaping enhancer accessibility
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- What's https://scholar.google.com/scholar_lookup?journal=Genome%20biology&title=GISTIC2.0%20facilitates%20sensitive%20and%20confident%20localization%20of%20the%20targets%20of%20focal%20somatic%20copy-number%20alteration%20in%20human%20cancers&author=CH%20Mermel&author=SE%20Schumacher&author=B%20Hill&author=ML%20Meyerson&author=R%20Beroukhim&volume=12&publication_year=2011&pages=R41&pmid=21527027&doi=10.1186/gb-2011-12-4-r41&'s gross income?
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Thirty-Fifth%20CTRC-AACR%20San%20Antonio%20Breast%20Cancer%20Symposium%20(San%20Antonio,%20TX)&title=Abstract%20S1-1:%20Relative%20effectiveness%20of%20letrozole%20compared%20with%20tamoxifen%20for%20patients%20with%20lobular%20carcinoma%20in%20the%20BIG%201-98%20trial&author=O%20Metzger&author=A%20Giobbie-Hurder&author=E%20Mallon&author=G%20Viale&author=E%20Winer&publication_year=2012& produce monthly?
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=The%20American%20journal%20of%20pathology&title=Differential%20loss%20of%20Ecadherin%20expression%20in%20infiltrating%20ductal%20and%20lobular%20breast%20carcinomas&author=R%20Moll&author=M%20Mitze&author=UH%20Frixen&author=W%20Birchmeier&volume=143&publication_year=1993&pages=1731-1742&pmid=8256859&?
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- How much does https://scholar.google.com/scholar_lookup?journal=Genome%20medicine&title=Computational%20purification%20of%20individual%20tumor%20gene%20expression%20profiles%20leads%20to%20significant%20improvements%20in%20prognostic%20prediction&author=G%20Quon&author=S%20Haider&author=AG%20Deshwar&author=A%20Cui&author=PC%20Boutros&volume=5&publication_year=2013&pages=29&pmid=23537167&doi=10.1186/gm433& rake in every month?
- Monthly income for https://doi.org/10.1093/hmg/8.4.607
- How much profit does https://scholar.google.com/scholar_lookup?journal=Human%20molecular%20genetics&title=Germline%20E-cadherin%20gene%20(CDH1)%20mutations%20predispose%20to%20familial%20gastric%20cancer%20and%20colorectal%20cancer&author=FM%20Richards&author=SA%20McKee&author=MH%20Rajpar&author=TR%20Cole&author=DG%20Evans&volume=8&publication_year=1999&pages=607-610&pmid=10072428&doi=10.1093/hmg/8.4.607& generate?
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- How much does https://scholar.google.com/scholar_lookup?journal=International%20journal%20of%20cancer%20Journal%20international%20du%20cancer&title=Epigenetic%20and%20genetic%20alterations%20of%20APC%20and%20CDH1%20genes%20in%20lobular%20breast%20cancer:%20relationships%20with%20abnormal%20E-cadherin%20and%20catenin%20expression%20and%20microsatellite%20instability&author=D%20Sarrio&author=G%20Moreno-Bueno&author=D%20Hardisson&author=C%20Sanchez-Estevez&author=M%20Guo&volume=106&publication_year=2003&pages=208-215&pmid=12800196&doi=10.1002/ijc.11197& pull in monthly?
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- What's https://scholar.google.com/scholar_lookup?journal=Genome%20research&title=Epigenetic%20switch%20involved%20in%20activation%20of%20pioneer%20factor%20FOXA1-dependent%20enhancers&author=AA%20Serandour&author=S%20Avner&author=F%20Percevault&author=F%20Demay&author=M%20Bizot&volume=21&publication_year=2011&pages=555-565&pmid=21233399&doi=10.1101/gr.111534.110&'s gross income?
- Income figures for https://doi.org/10.1158/0008-5472.CAN-13-2779
- How much money does https://scholar.google.com/scholar_lookup?journal=Cancer%20research&title=Invasive%20lobular%20carcinoma%20cell%20lines%20are%20characterized%20by%20unique%20estrogen-mediated%20gene%20expression%20patterns%20and%20altered%20tamoxifen%20response&author=MJ%20Sikora&author=KL%20Cooper&author=A%20Bahreini&author=S%20Luthra&author=G%20Wang&volume=74&publication_year=2014&pages=1463-1474&pmid=24425047&doi=10.1158/0008-5472.CAN-13-2779& generate?
- What's the revenue for https://doi.org/10.1038/nrm3330?
- https://scholar.google.com/scholar_lookup?journal=Nature%20reviews%20Molecular%20cell%20biology&title=The%20functions%20and%20regulation%20of%20the%20PTEN%20tumour%20suppressor&author=MS%20Song&author=L%20Salmena&author=PP%20Pandolfi&volume=13&publication_year=2012&pages=283-296&pmid=22473468&doi=10.1038/nrm3330&'s financial summary
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- How much does https://scholar.google.com/scholar_lookup?journal=Frontiers%20in%20bioscience&title=Tyrosine%20kinase%202%20(TYK2)%20in%20cytokine%20signalling%20and%20host%20immunity&author=B%20Strobl&author=D%20Stoiber&author=V%20Sexl&author=M%20Mueller&volume=16&publication_year=2011&pages=3214-3232&pmid=21622231&doi=10.2741/3908& pull in?
- What are the total earnings of https://doi.org/10.1101/gr.139469.112?
- How much profit does https://scholar.google.com/scholar_lookup?journal=Genome%20research&title=GATA3%20acts%20upstream%20of%20FOXA1%20in%20mediating%20ESR1%20binding%20by%20shaping%20enhancer%20accessibility&author=V%20Theodorou&author=R%20Stark&author=S%20Menon&author=JS%20Carroll&volume=23&publication_year=2013&pages=12-22&pmid=23172872&doi=10.1101/gr.139469.112& make?
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- How much does https://scholar.google.com/scholar_lookup?journal=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20of%20the%20United%20States%20of%20America&title=Significance%20analysis%20of%20microarrays%20applied%20to%20the%20ionizing%20radiation%20response&author=VG%20Tusher&author=R%20Tibshirani&author=G%20Chu&volume=98&publication_year=2001&pages=5116-5121&pmid=11309499&doi=10.1073/pnas.091062498& bring in each month?
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- How much money does https://scholar.google.com/scholar_lookup?journal=Bioinformatics&title=Inference%20of%20patient-specific%20pathway%20activities%20from%20multi-dimensional%20cancer%20genomics%20data%20using%20PARADIGM&author=CJ%20Vaske&author=SC%20Benz&author=JZ%20Sanborn&author=D%20Earl&author=C%20Szeto&volume=26&publication_year=2010&pages=i237-i245&pmid=20529912&doi=10.1093/bioinformatics/btq182& generate?
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- Revenue of https://scholar.google.com/scholar_lookup?journal=Genome%20research&title=Sequence%20features%20and%20chromatin%20structure%20around%20the%20genomic%20regions%20bound%20by%20119%20human%20transcription%20factors&author=J%20Wang&author=J%20Zhuang&author=S%20Iyer&author=X%20Lin&author=TW%20Whitfield&volume=22&publication_year=2012&pages=1798-1812&pmid=22955990&doi=10.1101/gr.139105.112&
- Learn about the earnings of https://doi.org/10.1093/nar/gku489
- Monthly income for https://scholar.google.com/scholar_lookup?journal=Nucleic%20acids%20research&title=Integrated%20RNA%20and%20DNA%20sequencing%20improves%20mutation%20detection%20in%20low%20purity%20tumors&author=MD%20Wilkerson&author=CR%20Cabanski&author=W%20Sun&author=KA%20Hoadley&author=V%20Walter&volume=42&publication_year=2014&pages=e107&pmid=24970867&doi=10.1093/nar/gku489&
- https://doi.org/10.1093/bioinformatics/btq170's revenue stream
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Bioinformatics&title=Consensus%20Cluster%20Plus:%20a%20class%20discovery%20tool%20with%20confidence%20assessments%20and%20item%20tracking&author=MD%20Wilkerson&author=DN%20Hayes&volume=26&publication_year=2010&pages=1572-1573&pmid=20427518&doi=10.1093/bioinformatics/btq170&
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- How much income does https://scholar.google.com/scholar_lookup?journal=J%20Roy%20Stat%20Soc%20B&title=Regularization%20and%20variable%20selection%20via%20the%20elastic%20net&author=H%20Zou&author=T%20Hastie&volume=67&publication_year=2005&pages=301-320& have?
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