
NCBI . NLM . NIH . GOV {
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Title[redir]:
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions - PMC
Description:
The endoplasmic reticulum (ER) has emerged as a critical regulator of cell fate. IRE1 is a transmembrane protein with kinase and RNase activities that is localized to the ER and that promotes resistance to ER stress. Here we showed a mechanism by ...
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Keywords {π}
mefs, doi, ireΞ±, figure, bnip, membrane, cells, treated, knockout, permeabilization, cell, grp, pubmed, google, scholar, stress, wildtype, analysis, cytosolic, protein, cytosol, pmc, death, antibody, merogfp, article, immunoblot, ire, leakage, bak, proteins, untreated, free, fractions, gapdh, calcium, mice, conditions, tunicamycin, expressing, contents, bax, luminal, untx, endoplasmic, mitochondrial, autophagy, reticulum, adenovirus, journal,
Topics {βοΈ}
agarose-conjugated anti-bcl2 antibody c-jun n-terminal kinase agarose-conjugated anti-bcl-2 antibody ire1-traf2-jnk pathway prevents anti-bak-n-terminus antibody glucose-stimulated ire1alpha activation rabbit anti-ha antibody c-terminal transmembrane domain additional n-glycosylation sites regulates ire1Ξ±-dependent decay pmc beta search plasmid encoding a1at-nhk leica ultracut cryo-ultramicrotome mero-gfp started leaking goat anti-gfp antibody anti-apoptotic proteins bcl2 regulated ire1-dependent decay mefs expressing mero-gfp dual live-cell imaging dual time-lapse imaging immuno-gold double labeling gel-filtration centrifuge columns mero-gfp ratio greater protein g-sepharose beads adenoviruses encoding wild-type pancreatic beta-cell death pro-apoptotic protein localized detected glycosylated a1at-nhk punctate lc3-gfp dots time-lapse ratio chase adenovirus encoding wild-type expressing wild-type bak ire1 signaling prevented wilcoxon signed-rank test creutzfeldt-jakob disease detected time-lapse ratio imaging pro-apoptotic bnip3 protein kinase-dead k599a mutant endonuclease-dead k907a-mutant hypoxia-inducible factor-1alpha er stress-related diseases nestin-cre transgenic mice pro-apoptotic proteins bax anti-apoptotic proteins bcl-2 supplementary materials included higher mero-gfp ratios anti-active bak antibody anti-bak-nt antibody bax/bak double knockout er stress-induced apoptosis
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- What's the income of https://scholar.google.com/scholar_lookup?journal=The%20Journal%20of%20clinical%20investigation&title=Wolfram%20syndrome%201%20gene%20negatively%20regulates%20ER%20stress%20signaling%20in%20rodent%20and%20human%20cells&author=SG%20Fonseca&volume=120&publication_year=2010&pages=744-755&pmid=20160352&doi=10.1172/JCI39678&?
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Analytics and Tracking {π}
- Google Analytics
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Libraries {π}
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Emails and Hosting {βοΈ}
Mail Servers:
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- dns1-ncbi.ncbi.nlm.nih.gov
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CDN Services {π¦}
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