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Keywords {🔍}

trnalookalikes, trnas, trna, lookalikes, trnareference, true, nuclear, mitochondrial, doi, pubmed, google, scholar, number, chromosomes, pmc, genes, article, entries, mismatches, loci, data, human, chromosome, free, genome, genomic, figure, file, lookalike, rna, sequence, additional, trnalookalike, found, distribution, transcribed, function, set, shown, allowed, enrichment, category, search, molecules, entry, pseudo, click, database, analysis, functional,

Topics {✒️}

encode rna-seq track pmc beta search encode rna-seq data anticodon tri-nucleotide matched van bortle previously uncharacterized trna-lookalikes correct trna-derived fragments jak2 protein-coding gene protein-coding pre-mrnas similar trna-reference gene encode project consortium trna-reference set exhibited matching trna-reference entry true trna-reference set observed trna-lookalikes reaches mitochondrial trna-reference entry lookalike/true trna gene transcribed trna-lookalikes revealed snogps web servers important protein-coding genes nuclear trna-lookalikes differs mitochondrial-specific sequences/molecules true trna-reference entries randomly selected spots publisher site pdf pmc disclaimer keck foundation grant deep sequencing data lengthy experimental investigations public archive trna-lookalikes genomic loci full-length sequences nih grant gm106047 trna-reference gene closest true trna previously reported numts nuclear/mitochondrial lookalikes compared produced requires additional data availability statements united states government biologically active entities adversely impact recognition combinatorial chemistry playground wobble modification deficiency del mar gonzalez trna biology studies manual comparative analysis full-length “hits” additional data file nucleic acids res

Questions {❓}

• Human mitochondrial tRNA quality control in health and disease: a channelling mechanism?
• In particular, we addressed the following two questions: (a) which tRNA-Reference entry can best serve as the “source template” of the tRNA-lookalike hit?
• There are many questions we seek to explore such as: Are some amino acids (anticodons) over-represented among the lookalikes, and, if so, which ones?
• TRNA modifications: necessary for correct tRNA-derived fragments during the recovery from stress?

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