
NCBI . NLM . NIH . GOV {
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Title[redir]:
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis - PMC
Description:
Necroptosis is a form of programmed cell death that depends on the activation of receptor interacting protein kinase-1 (RIPK1) and RIPK3 by receptors such as tumor necrosis factor (TNF) receptor-1. Structural studies indicate that activation of ...
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Keywords {🔍}
ripk, doi, cell, cells, death, activation, figure, necroptosis, caspase, pubmed, google, scholar, supplementary, oligomerization, protein, domain, dimerization, expressing, nec, pmc, rhim, complexes, article, kinase, complex, ripkxfv, treated, usa, free, necrosis, formation, data, tnf, oligomers, receptor, signaling, niht, constructs, consistent, necrosome, inhibition, domains, presence, absence, zvad, rip, rhimdependent, proteins, response, mlkl,
Topics {✒️}
caspase inhibitor z-val-ala-asp tnf-blocking reagent tnfr1-fc tumor necrosis factor receptor-interacting kinase-3-mediated pathway t2a-gfp-t2a-puromycin resistance cassette 200 ng/ml tnfr1-fc tnf-induced nf-kappab signal sds-page pre-cast gels endogenous ripk expression ripk1 inhibitor necrostatin-1 ripk3-fv fusion proteins �fkbpf36v point mutant fk506-binding protein tnfr-fc interferon regulatory factor standard anti-rat-hrp secondary nih-3t3 cells expressing protein–protein interactions involved large receptor-proximal complex full-length murine ripk3 mcherry/gfp double positivity similar induced-interaction systems tnf-induced cell death lipofectamine sirna-max reagent n-terminal kinase domain helper-dependent retroviral transduction tnf-induced necrosis cells expressing ripk3δrhim-1xfv nih-3t3 cells transduced pmc beta search blocks tnf-induced necroptosis immunoglobulin heavy receptor-driven necroptosis involve tris-free np40 buffer n-terminal flag tag pbabe-puro retroviral vectors cells expressing ripk3-1xfv tnf-mediated ripk3 activation dai/zbp1/dlm-1 complexes tnf-induced ripk3 activation rip3–rip3 homo-interaction cells expressing ripk3-2xfv c-terminal rhim means c-terminal death domain rip kinases interact yang z dimerizer-induced cell death murine fibroblast line c-terminal rhim domain tnf-driven ripk3 activation
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Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi