
NCBI . NLM . NIH . GOV {
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Title[redir]:
Deadenylation of mRNA by the CCR4โNOT complex in Drosophila: molecular and developmental aspects - PMC
Description:
Controlled shortening of the poly(A) tail of mRNAs is the first step in eukaryotic mRNA decay and can also be used for translational inactivation of mRNAs. The CCR4โNOT complex is the most important among a small number of deadenylases, enzymes ...
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Keywords {๐}
complex, ccrnot, doi, google, scholar, pubmed, deadenylation, drosophila, mrna, pmc, article, free, cells, cell, proteins, mrnas, ccr, rna, biol, role, stem, decay, conserved, pop, subunits, temme, protein, domain, binding, nanos, mol, deadenylase, chen, polya, translational, caf, germline, function, gene, regulation, interaction, yeast, human, early, repression, izaurralde, wahle, activity, mammalian, specific,
Topics {โ๏ธ}
mg-dependent endonuclease-related proteins cell-free system derived pmc beta search [google scholar] horiuchi argonaute2-cleaved precursor micrornas tissue-specific rnai screen n-terminal deletion variant cell-free system mrna cap-interacting deadenylase puf protein-mediated deadenylation x-ray structure revealing caf40/cnot9 binding domain conserved n-terminal domain not1 n-terminal domain mirna-mediated gene silencing rapid atp-dependent deadenylation coiledโcoil domain microrna-mediated translational repression individual rnai-mediated depletion affect pabp-dependent deadenylation distant caf1/pop2 relative leucine-rich repeat monoclonal antibody directed au-rich elements pan gu kinase stable reporter mrna strong hypomorphic allele smaug rna-binding protein steady-state levels smaug-mediated translational repression human gw182-pabc interaction n-terminal fragment active site residues mutants affecting pan2/pan3 pmc disclaimer c-terminal homologous c-terminal effector sre-dependent deadenylation observed n-terminal sequences active site mutant not1-not2-not5 module license information pmcid x-ray crystallography publisher site pdf not10/not11 binding domain exonuclease-endonuclease-phosphatase pair binds tightly c-terminal domain c-terminal portion nuclear cajal bodies
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- How much income does https://scholar.google.com/scholar_lookup?journal=RNA%20Biol.&title=C2ORF29/CNOT11%20and%20CNOT10%20form%20a%20new%20module%20of%20the%20CCR4-NOT%20complex.&author=F.%20Mauxion&author=B.%20Pr%C3%A8ve&author=B.%20S%C3%A8raphin&volume=10&publication_year=2013&pages=267-276&pmid=23232451&doi=10.4161/rna.23065& have?
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- What's the profit of https://scholar.google.com/scholar_lookup?journal=J.%20Cell%20Biol.&title=Gawky%20is%20a%20component%20of%20cytoplasmic%20mRNA%20processing%20bodies%20required%20for%20early%20Drosophila%20development.&author=M.%20D.%20Schneider&author=N.%20Najand&author=S.%20Chaker&author=J.%20M.%20Pare&author=J.%20Haskins&volume=174&publication_year=2006&pages=349-358&pmid=16880270&doi=10.1083/jcb.200512103&?
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