
NCBI . NLM . NIH . GOV {
}
Title[redir]:
A highly expressed miR-101 isomiR is a functional silencing small RNA - PMC
Description:
MicroRNAs (miRNAs) are short non-coding regulatory RNAs that control gene expression usually producing translational repression and gene silencing. High-throughput sequencing technologies have revealed heterogeneity at length and sequence level for ...
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Keywords {π}
isomir, doi, expression, variants, pubmed, google, scholar, mirna, human, pmc, ago, genes, cells, article, free, cell, gene, microrna, rna, isomirs, figure, targets, file, sequence, sequences, data, shsyy, seed, transfected, control, brain, expressed, mrna, levels, shown, additional, nucleotides, sequencing, risc, number, target, silencing, abundant, analysis, total, ezh, mirnas, trimming, samples, reference,
Topics {βοΈ}
de/apps/zmf/mirwalk/index increased bace1/beta-secretase expression pri-mirna post-transcriptional editing competing interests exist microrna cluster mir-29a/b-1 pmc beta search mouse nih-3t3 cells joint genome-wide profiling sh-sy5y neuroblastoma cells cold phosphate-buffered saline 8%-12% sds-page gels hif-1alpha/hif-1beta anti-flag antibody shows references xie high-throughput sequencing technologies differentiated sh-sy5y cells competing interests 3β-biotin-5β-isomir-101 versus 3β-biotin-mir-101 sh-sy5y cells decreased specific rt-qpcr assays negative post-transcriptional regulators rnase-free water sh-sy5y-ago2-flag rnase-free bsa rnase-free dnase transfected sh-sy5y cells sh-sy5y cells transfected rna-induced silencing complex nyap2 expression anti-correlated scn3b expression anti-correlated small-rna sequencing datasets high-throughput sequencing data candidate age-related genes modulating age-related genes d-ago2 crossing thresholds supplementary materials included polymerase activation/denaturation cycle mirna/mrna binding leads mir-101-sequence-gene pair predicted specific rt-qpcrs determinations abbreviations mir control d-ago2 antibody de hoon mj isomir-dependent differential output similar biological pathways reveals argonaute association sh-sy5y cells amyloid precursor protein tumor suppressive functions minones-moyano
Questions {β}
- Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
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- What's https://scholar.google.com/scholar_lookup?journal=J%20Biol%20Chem&title=MicroRNA-101%20regulates%20amyloid%20precursor%20protein%20expression%20in%20hippocampal%20neurons&author=E%20Vilardo&author=C%20Barbato&author=M%20Ciotti&author=C%20Cogoni&author=F%20Ruberti&volume=285&issue=24&publication_year=2010&pages=18344-18351&pmid=20395292&doi=10.1074/jbc.M110.112664&'s gross income?
- What's https://doi.org/10.1186/1476-4598-9-108's gross income?
- What's https://scholar.google.com/scholar_lookup?journal=Mol%20Cancer&title=MicroRNA-101%20negatively%20regulates%20Ezh2%20and%20its%20expression%20is%20modulated%20by%20androgen%20receptor%20and%20HIF-1alpha/HIF-1beta&author=P%20Cao&author=Z%20Deng&author=M%20Wan&author=W%20Huang&author=SD%20Cramer&volume=9&publication_year=2010&pages=108&pmid=20478051&doi=10.1186/1476-4598-9-108&'s gross income?
- How much profit does https://doi.org/10.4049/jimmunol.1000798 make?
- How much does https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=MicroRNA-101%20targets%20MAPK%20phosphatase-1%20to%20regulate%20the%20activation%20of%20MAPKs%20in%20macrophages&author=QY%20Zhu&author=Q%20Liu&author=JX%20Chen&author=K%20Lan&author=BX%20Ge&volume=185&issue=12&publication_year=2010&pages=7435-7442&pmid=21068409&doi=10.4049/jimmunol.1000798& generate monthly?
- Revenue of https://doi.org/10.1186/1471-2164-11-716
- What is the earnings of https://scholar.google.com/scholar_lookup?journal=BMC%20Genomics&title=New%20methods%20for%20next%20generation%20sequencing%20based%20microRNA%20expression%20profiling&author=HP%20Buermans&author=Y%20Ariyurek&author=G%20van%20Ommen&author=JT%20den%20Dunnen&volume=11&publication_year=2010&pages=716&pmid=21171994&doi=10.1186/1471-2164-11-716&?
- Find out how much https://doi.org/10.1097/JTO.0b013e318208eb35 earns monthly
- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=J%20Thorac%20Oncol&title=MicroRNA-101%20exerts%20tumor-suppressive%20functions%20in%20non-small%20cell%20lung%20cancer%20through%20directly%20targeting%20enhancer%20of%20zeste%20homolog%202&author=JG%20Zhang&author=JF%20Guo&author=DL%20Liu&author=Q%20Liu&author=JJ%20Wang&volume=6&issue=4&publication_year=2011&pages=671-678&pmid=21270667&doi=10.1097/JTO.0b013e318208eb35&
- How much does https://doi.org/10.1158/0008-5472.CAN-08-3114 bring in each month?
- How much does https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=The%20putative%20tumor%20suppressor%20microRNA-101%20modulates%20the%20cancer%20epigenome%20by%20repressing%20the%20polycomb%20group%20protein%20EZH2&author=JM%20Friedman&author=G%20Liang&author=CC%20Liu&author=EM%20Wolff&author=YC%20Tsai&volume=69&issue=6&publication_year=2009&pages=2623-2629&pmid=19258506&doi=10.1158/0008-5472.CAN-08-3114& pull in monthly?
- What are the total earnings of https://doi.org/10.1126/science.1165395?
- How much does https://scholar.google.com/scholar_lookup?journal=Science&title=Genomic%20loss%20of%20microRNA-101%20leads%20to%20overexpression%20of%20histone%20methyltransferase%20EZH2%20in%20cancer&author=S%20Varambally&author=Q%20Cao&author=RS%20Mani&author=S%20Shankar&author=X%20Wang&volume=322&issue=5908&publication_year=2008&pages=1695-1699&pmid=19008416&doi=10.1126/science.1165395& pull in monthly?
- See how much https://doi.org/10.1038/emboj.2011.331 makes per month
- https://scholar.google.com/scholar_lookup?journal=EMBO%20J&title=microRNA-101%20is%20a%20potent%20inhibitor%20of%20autophagy&author=LB%20Frankel&author=J%20Wen&author=M%20Lees&author=M%20Hoyer-Hansen&author=T%20Farkas&volume=30&issue=22&publication_year=2011&pages=4628-4641&pmid=21915098&doi=10.1038/emboj.2011.331&'s revenue stream
- https://doi.org/10.1016/j.bbrc.2010.12.053 income
- https://scholar.google.com/scholar_lookup?journal=Biochem%20Biophys%20Res%20Commun&title=MicroRNA-101%20downregulates%20Alzheimer%E2%80%99s%20amyloid-beta%20precursor%20protein%20levels%20in%20human%20cell%20cultures%20and%20is%20differentially%20expressed&author=JM%20Long&author=DK%20Lahiri&volume=404&issue=4&publication_year=2011&pages=889-895&pmid=21172309&doi=10.1016/j.bbrc.2010.12.053&'s financial summary
- What's https://doi.org/10.1038/nn.2183's gross income?
- What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Nat%20Neurosci&title=miR-19,%20miR-101%20and%20miR-130%20co-regulate%20ATXN1%20levels%20to%20potentially%20modulate%20SCA1%20pathogenesis&author=Y%20Lee&author=RC%20Samaco&author=JR%20Gatchel&author=C%20Thaller&author=HT%20Orr&volume=11&issue=10&publication_year=2008&pages=1137-1139&pmid=18758459&doi=10.1038/nn.2183&?
- Profit of https://doi.org/10.1093/nar/gkp1127
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=Nucleic%20Acids%20Res&title=SeqBuster,%20a%20bioinformatic%20tool%20for%20the%20processing%20and%20analysis%20of%20small%20RNAs%20datasets,%20reveals%20ubiquitous%20miRNA%20modifications%20in%20human%20embryonic%20cells&author=L%20Pantano&author=X%20Estivill&author=E%20Marti&volume=38&issue=5&publication_year=2010&pages=e34&pmid=20008100&doi=10.1093/nar/gkp1127&?
- How much revenue does https://doi.org/10.1371/journal.pbio.0030085 generate?
- How much does https://scholar.google.com/scholar_lookup?journal=PLoS%20Biol&title=Principles%20of%20microRNA-target%20recognition&author=J%20Brennecke&author=A%20Stark&author=RB%20Russell&author=SM%20Cohen&volume=3&issue=3&publication_year=2005&pages=e85&pmid=15723116&doi=10.1371/journal.pbio.0030085& earn?
- How much profit does https://doi.org/10.1093/nar/gkr688 generate?
- How much does https://scholar.google.com/scholar_lookup?journal=Nucleic%20Acids%20Res&title=miRDeep2%20accurately%20identifies%20known%20and%20hundreds%20of%20novel%20microRNA%20genes%20in%20seven%20animal%20clades&author=MR%20Friedlander&author=SD%20Mackowiak&author=N%20Li&author=W%20Chen&author=N%20Rajewsky&volume=40&issue=1&publication_year=2012&pages=37-52&pmid=21911355&doi=10.1093/nar/gkr688& bring in each month?
- What's the monthly income of https://doi.org/10.1038/nrg2843?
- https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Genet&title=The%20widespread%20regulation%20of%20microRNA%20biogenesis,%20function%20and%20decay&author=J%20Krol&author=I%20Loedige&author=W%20Filipowicz&volume=11&issue=9&publication_year=2010&pages=597-610&pmid=20661255&doi=10.1038/nrg2843&'s financial summary
- How much income does https://doi.org/10.1016/j.molcel.2008.09.014 have?
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Mol%20Cell&title=Lin28%20mediates%20the%20terminal%20uridylation%20of%20let-7%20precursor%20MicroRNA&author=I%20Heo&author=C%20Joo&author=J%20Cho&author=M%20Ha&author=J%20Han&volume=32&issue=2&publication_year=2008&pages=276-284&pmid=18951094&doi=10.1016/j.molcel.2008.09.014&
- What's the total monthly financial gain of https://doi.org/10.1186/gb-2011-12-12-r126?
- How much money does https://scholar.google.com/scholar_lookup?journal=Genome%20Biol&title=MicroRNAs%20and%20their%20isomiRs%20function%20cooperatively%20to%20target%20common%20biological%20pathways&author=N%20Cloonan&author=S%20Wani&author=Q%20Xu&author=J%20Gu&author=K%20Lea&volume=12&issue=12&publication_year=2011&pages=R126&pmid=22208850&doi=10.1186/gb-2011-12-12-r126& make?
- See how much https://doi.org/10.1186/1758-907X-2-4 makes per month
- How much does https://scholar.google.com/scholar_lookup?journal=Silence&title=A%205%E2%80%99-uridine%20amplifies%20miRNA/miRNA*%20asymmetry%20in%20Drosophila%20by%20promoting%20RNA-induced%20silencing%20complex%20formation&author=H%20Seitz&author=JS%20Tushir&author=PD%20Zamore&volume=2&publication_year=2011&pages=4&pmid=21649885&doi=10.1186/1758-907X-2-4& bring in each month?
- What is the earnings of https://doi.org/10.1186/1758-907X-1-12?
- What's the financial gain of https://scholar.google.com/scholar_lookup?journal=Silence&title=Naturally%20occurring%20variations%20in%20sequence%20length%20creates%20microRNA%20isoforms%20that%20differ%20in%20argonaute%20effector%20complex%20specificity&author=HA%20Ebhardt&author=A%20Fedynak&author=RP%20Fahlman&volume=1&issue=1&publication_year=2010&pages=12&pmid=20534119&doi=10.1186/1758-907X-1-12&?
- How much revenue does https://doi.org/10.4161/rna.8.1.14300 produce monthly?
- Earnings of https://scholar.google.com/scholar_lookup?journal=RNA%20Biol&title=Deep-sequencing%20of%20human%20Argonaute-associated%20small%20RNAs%20provides%20insight%20into%20miRNA%20sorting%20and%20reveals%20Argonaute%20association%20with%20RNA%20fragments%20of%20diverse%20origin&author=AM%20Burroughs&author=Y%20Ando&author=MJ%20de%20Hoon&author=Y%20Tomaru&author=H%20Suzuki&volume=8&issue=1&publication_year=2011&pages=158-177&pmid=21282978&doi=10.4161/rna.8.1.14300&
- https://doi.org/10.1093/nar/gks705's total income per month
- What's https://scholar.google.com/scholar_lookup?journal=Nucleic%20Acids%20Res&title=microRNAs%20associated%20with%20the%20different%20human%20Argonaute%20proteins&author=A%20Dueck&author=C%20Ziegler&author=A%20Eichner&author=E%20Berezikov&author=G%20Meister&volume=40&issue=19&publication_year=2012&pages=9850-9862&pmid=22844086&doi=10.1093/nar/gks705&'s gross income?
- How much revenue does https://doi.org/10.1093/hmg/ddr210 bring in?
- Learn how profitable https://scholar.google.com/scholar_lookup?journal=Hum%20Mol%20Genet&title=MicroRNA%20profiling%20of%20Parkinson%E2%80%99s%20disease%20brains%20identifies%20early%20downregulation%20of%20miR-34b/c%20which%20modulate%20mitochondrial%20function&author=E%20Minones-Moyano&author=S%20Porta&author=G%20Escaramis&author=R%20Rabionet&author=S%20Iraola&volume=20&issue=15&publication_year=2011&pages=3067-3078&pmid=21558425&doi=10.1093/hmg/ddr210& is on a monthly basis
- How much revenue does https://doi.org/10.1371/journal.pgen.1002481 generate?
- How much cash flow does https://scholar.google.com/scholar_lookup?journal=PLoS%20Genet&title=A%20pathogenic%20mechanism%20in%20Huntington%E2%80%99s%20disease%20involves%20small%20CAG-repeated%20RNAs%20with%20neurotoxic%20activity&author=M%20Banez-Coronel&author=S%20Porta&author=B%20Kagerbauer&author=E%20Mateu-Huertas&author=L%20Pantano&volume=8&issue=2&publication_year=2012&pages=e1002481&pmid=22383888&doi=10.1371/journal.pgen.1002481& have monthly?
- How much profit does https://doi.org/10.1016/j.ymeth.2007.04.007 generate?
- What are the earnings of https://scholar.google.com/scholar_lookup?journal=Methods&title=Isolation%20of%20microRNA%20targets%20using%20biotinylated%20synthetic%20microRNAs&author=UA%20Orom&author=AH%20Lund&volume=43&issue=2&publication_year=2007&pages=162-165&pmid=17889804&doi=10.1016/j.ymeth.2007.04.007&?
- How much money does https://github.com/ncbi generate?
- What is the monthly revenue of https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323?
- Earnings of https://www.nlm.nih.gov/web_policies.html
- https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office's revenue stream
- Monthly income for https://www.hhs.gov/vulnerability-disclosure-policy/index.html
- How much revenue does https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Ajournal produce monthly?
- How much revenue does https://www.nlm.nih.gov/accessibility.html generate?
- How much does https://www.nlm.nih.gov/careers/careers.html net monthly?
- What's the financial outcome of https://www.nlm.nih.gov/?
- What's https://www.nih.gov/'s gross income?
- What's the revenue for https://www.hhs.gov/?
- What's the financial intake of https://www.usa.gov/?
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