NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3289102/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC3289102/. The analysis below is for the second page.
Title[redir]:
The potential for caspases in drug discovery - PMC
Description:
Caspases are a family of proteases that are involved in the execution of apoptosis and the inflammatory response. A plethora of diseases occur as a result of the dysregulation of apoptosis and inflammation, and caspases have been targeted as a ...
Title[redir]:
The potential for caspases in drug discovery - PMC
Description:
Caspases are a family of proteases that are involved in the execution of apoptosis and the inflammatory response. A plethora of diseases occur as a result of the dysregulation of apoptosis and inflammation, and caspases have been targeted as a ...
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What CMS is ncbi.nlm.nih.gov built with?
Custom-built
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Traffic Estimate {📈}
What is the average monthly size of ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
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How Does Ncbi.nlm.nih.gov Make Money? {💸}
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Keywords {🔍}
caspase, doi, google, scholar, pubmed, inhibitors, procaspase, caspases, active, site, inhibitor, cell, apoptosis, activation, clinical, design, allosteric, interface, figure, dimer, drug, liver, treatment, smallmolecule, pmc, death, enzyme, inhibition, demonstrated, inflammatory, cancer, structure, binding, chem, trials, cells, acid, pralnacasan, peptidomimetic, development, emricasan, diseases, strategy, activators, aspartic, disease, additionally, based, family, therapeutic,
Topics {✒️}
iso/leu/val-glu-xaa-asp motif [17] 2-ethoxy-5-oxo-tetrahydro-furan-3-yl asp-glu-xaa-asp motif mammalian interleukin-1β-converting enzyme 5-fluoro-1h-indole-2-carboxylic acid /files/research/pipeline/2008_0228/pipeline_2008_0228 interleukin-1β-converting enzyme/caspase-1 peptide inhibitor ac-trp-glu interleukin-1β-converting enzyme interleukin-1β converting enzyme adjacent electron-deficient atom il-1β-converting enzyme reversible inhibitor ac-wehd-cho il-1 β-converting enzyme pmc beta search bak/bax double-knockout collagenase-induced arthritis model fas-mediated liver injury identify small-molecule activators nitric oxide-releasing derivative converting enzyme/caspase-1 inhibitor small-molecule caspase activators develop small-molecule inhibitors solvent-accessible cysteine residues placebo-controlled clinical trial direct small-molecule activator small-molecule caspase inhibitors long-term animal studies ischemia-reperfusion liver injury limiting zinc-mediated inhibition aza-peptide michael acceptors irreversible pan-caspase inhibitor ice/ced-3 protease family ligand-free form small-molecule inhibitors designed design pan-caspase inhibitors small-molecule activators caspase-1-specific peptidomimetic inhibitors caspase-1-specific inhibitors based human preservation injury pyrrolidine-2-carboxylic acid small-molecule activator forms numerous interactions including hydrogen bonds hydrogen bond interaction small-molecule inhibitors small-molecule inhibitor small-molecule drug observable side effects individual sequence specificities
Social Networks {👍}(6)
External Links {🔗}(118)
- Monthly income for https://doi.org/10.1038/sj.cdd.4402047
- Get to know https://scholar.google.com/scholar_lookup?journal=Cell%20Death%20Differ&title=Caspases%20in%20cell%20survival,%20proliferation%20and%20differentiation&author=M%20Lamkanfi&author=N%20Festjens&author=W%20Declercq&author=T%20Vanden%20Berghe&author=P%20Vandenabeele&volume=14&issue=1&publication_year=2007&pages=44-55&pmid=17053807&doi=10.1038/sj.cdd.4402047&'s earnings
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- How much income does https://doi.org/10.1124/jpet.106.111344 have?
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- What's the revenue for https://scholar.google.com/scholar_lookup?title=Design%20of%20caspase%20inhibitors%20as%20potential%20clinical%20agents&author=H%20Eda&publication_year=2009&?
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- What's the financial gain of https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Drug%20Discov&title=Targeting%20IL-1%20in%20inflammatory%20disease:%20New%20opportunities%20for%20therapeutic%20intervention&author=M%20Braddock&author=A%20Quinn&volume=3&issue=4&publication_year=2004&pages=330-339&pmid=15060528&doi=10.1038/nrd1342&?
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- How much does https://scholar.google.com/scholar_lookup?journal=J%20Med%20Chem&title=First-in-class%20pan%20caspase%20inhibitor%20developed%20for%20the%20treatment%20of%20liver%20disease&author=SD%20Linton&author=T%20Aja&author=RA%20Armstrong&author=X%20Bai&author=L-S%20Chen&volume=48&issue=22&publication_year=2005&pages=6779-6782&pmid=16250635&doi=10.1021/jm050307e& pull in monthly?
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