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cells, mcl, aml, fig, cell, mice, doi, tamoxifen, supplemental, pubmed, google, scholar, expression, bcl, treatment, myeloid, survival, bclxl, human, pmc, transformed, article, lines, leukemia, transduced, deletion, viability, free, gfp, leukemic, mllenl, treated, protein, proteins, mclflflcre, cre, sustained, loss, mclflcre, acute, family, death, apoptosis, prosurvival, gene, untreated, vitro, stem, retroviral, chen,

Topics {✒️}

lin−c-kit+sca-1− myeloid progenitors mll-enl/neo transformed mcl-1fl/fl pan-caspase inhibitor qvd-oph lineage marker−sca-1+c-kit+ mll-enl/neo expression vector mice bearing mll-enl-induced retrovirus-mediated gene transfer c-kit overexpression/mutations tetracycline-induced rnai-mediated knockdown retroviruses encoding mll-enl pmc beta search mll-enl-induced aml somatic copy-number alteration op9-dl1 feeder cells mll-af9 retroviral constructs acute myeloid leukemia-m2 bone marrow cells mixl1-transduced marrow cells normal hematopoietic stem aml-derived cell lines hematopoietic stem cells similar transduction/transplantation models anti-cancer therapy kills debilitate creert2-mediated recombination creer-hcd2 retroviral construct anti-apoptotic genes mcl-1 �bcl-2-regulated” apoptotic pathway administering aml-burdened mice n-ras aml cells anti-apoptotic bcl-xl relapsed mcl-1fl/fl facs-sorted nontransformed lsk relapsed bcl-xfl/fl rosa26-cre-ert2 mice org/cgi/doi/10 cre-ert2 protein expression aml1-eto9a retroviral construct mll-af9-induced nontransformed stem cells cre/+ aml-burdened mice cell lines derived derived cell lines aml1-eto9a transduced cells stem cell technologies bone marrow gfp+ mcl-1fl/fl leukemia stem cells pro-survival bcl-2 proteins tetracycline-regulated rnai activated cre recombinase

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