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Title[redir]:
Shaping sound in space: the regulation of inner ear patterning - PMC
Description:
The inner ear is one of the most morphologically elaborate tissues in vertebrates, containing a group of mechanosensitive sensory organs that mediate hearing and balance. These organs are arranged precisely in space and contain intricately patterned ...
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Keywords {🔍}
ear, signaling, google, scholar, doi, pubmed, development, fgf, cells, otic, sensory, shh, patterning, cell, otocyst, bmp, cochlea, wnt, signals, pmc, organ, domain, article, free, hair, dev, cochlear, placode, mouse, expression, neural, markers, fate, duct, gli, gradients, axis, dorsal, anterior, posterior, prosensory, biol, fig, zebrafish, gradient, bok, ventral, region, outer, box,
Topics {✒️}
fluid-filled toroidal-shaped ducts pmc beta search sox2-expressing sensory-competent cells amino-terminal cleavage product bmp-binding endothelial regulator n-terminal repressor fragment similar mirror-image duplications [google scholar] mann [google scholar] stevens mirror-image posterior domains mirror-image symmetric prepattern mirror-image anterior domains fine-tune structural variations [google scholar] puligilla partial mirror-image duplications pax2-expressing progenitor domain [google scholar] groves local cell-cell interactions mirror-image anterior duplications epithelium-lined chambers called mirror-image duplicated ear wnt3a double-mutant ears partial mirror-image duplication competent pre-placodal ectoderm sox2-expressing supporting cells fibroblast growth factors prox1-positive supporting cells fluid-filled cochlear duct single transcription factor fgf20 function-blocking antibodies bone morphogenetic proteins regulates cellular patterning otic placode/vesicle differ otic-epibranchial progenitor domain sensory/outer sulcus border otic-epidermal fate choice differentiating sensory patches fgf3 mutant lim-absent sensory organs versus retinoic acid signaling binds chordin/bmp anterior/posterior repressor gradient provide patterning information fluid-filled ducts long-range sclerotome induction sound-detecting cochlea emerging rapidly cease responding mirror-image duplications otic-epibranchial placode domain show wnt signaling
Questions {❓}
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