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Title[redir]:
Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy - PMC
Description:
Immune-regulated pathways influence multiple aspects of cancer development. In this article we demonstrate that both macrophage abundance and T-cell abundance in breast cancer represent prognostic indicators for recurrence-free and overall survival. ...
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Keywords {đ}
cancer, doi, breast, mice, tumor, fig, cells, expression, mammary, tumors, google, scholar, pubmed, ptx, mmtvpymt, patients, supplementary, immune, treated, plx, article, tams, pmc, treatment, infiltration, tissue, cell, analysis, response, chemotherapy, tam, free, macrophages, survival, csf, data, mrna, macrophage, recruitment, significant, therapy, cohort, primary, lymphocytes, metastasis, signature, cytotoxic, density, antitumor, human,
Topics {âď¸}
cd45+cd11blow/âly6câcd22âly6gâcd11chighmhciihigh dcs tumor-infiltrating d45+ly6gâly6clowcd11b+f4/80+ macrophages cd45+cd11b+ly6câly6gâf4/80+ tam recruitment tumor-infiltrating cd45+ly6gâly6clowcd11b+f4/80+ tams cd45+cd11blow/âcd19âly6gâly6clowcd11chighmhciihigh dcs cd45+ly6gâly6câcd11b+f4/80+ tams cd45+cd11b+ly6câly6gâf4/80+ tams colony-stimulating factor-1-related proteins cd45+ly6gâly6clowcd11blow/â cd11chighmhciihi dcs cd45+cd11b+ly6clowly6gâf4/80+ tams colony-stimulating factor-1 receptor oncogenic b-raf kinase cd45+cd11b+ly6gâly6clowf4/80+ cd8+ t-cellâdependent manner mmtv-pmecsâderived mecs treated cd45+cd11b+ly6gâly6chigh cd8+ t-cellâdependent response macrophage-deficient op/op mouse tumor-infiltrating cd45+cd3+cd8+ late-stage mmtv-pymt mice linâ/lowhla-drâcd33+cd11b+ cd68low/cd4low/cd8high immune profiles part cd8+ t-cellâdependent cd8+ t-cellâdependent mechanisms cd68low/cd4low/cd8high immune signature pbs-perfused mmtv-pymt mice cd14+hla-drâ/low imcs cd11b+gr1+ly6g+ cells cd45+cd11b+ly6ghigh imcs cd45+cd11b+ly6ghi imcs brooks/cole advanced books orthotopic tumorâbearing mice orthotopic pymt-derived tumors cd14+hla-drâ/low cells cd8+ t-cellâdependent csf-1 receptor-mediated regulation immunosuppressive cd11b+ly6g+ cells myeloid-derived suppressor cells colony stimulating factor-1 colony-stimulating factor-1 colony-stimulating factor 1 cd45+cd11b+cd14+ macrophages rfs comparing cd68high/cd4high/cd8low cd68/cd4/cd8 immune signature cd8+ t-cell infiltration malignant pymt-derived mecs mmtv-pymtâderived mecs cd8 t-cell ratios gr1+ccr2+cx3cr1low imcs mmtv-pymt mice progress
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- M-CSF (monocyte colony stimulating factor) and M-CSF receptor expression by breast tumour cells: M-CSF mediated recruitment of tumour infiltrating monocytes?
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- https://doi.org/10.1016/j.cytogfr.2009.11.009 income
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