
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Prevention of Torsade de Pointes in Hospital Settings: A Scientific Statement From the American Heart Association and the American College of Cardiology Foundation: Endorsed by the American Association of Critical-Care Nurses and the International Society for Computerized Electrocardiology - PMC
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Keywords {π}
doi, tdp, pubmed, google, scholar, risk, drugs, drug, patients, interval, pointes, ventricular, ecg, qtc, cardiac, prolongation, heart, lqts, long, hospital, druginduced, syndrome, monitoring, clinical, repolarization, torsade, torsades, factors, arrhythmia, measurement, lead, cardiol, genetic, settings, wave, congenital, block, death, potassium, med, pmc, intervals, sudden, increase, patient, potential, roden, fibrillation, rhythm, antiarrhythmic,
Topics {βοΈ}
kcne2-encoded Ξ²-subunit resulted typical short-long-short sequence short-long-short cycle sequence drug-induced long-qt syndrome sanofi-aventis/ bristol-myers squibb lqt6-causing missense mutation potentially cata-strophic event short-long-short sequence long-short initiating sequence nonsynonymous single-nucleotide polymorphism increased short-term variability acc/aha/esc 2006 guidelines real-time qt/qtc monitoring short-long-short cycles l-type calcium channels risperidone-facilitated triggered activity short-long-short pattern drug-induced long qt abbott poc/i-statβ pmc beta search pmc copyright notice drug-induced qt prolongation major lqts-susceptibility genes rate-corrected qt interval short-long-short r drug-induced cardiac arrhythmias verapamil-induced qt prolongation long-qt disease genes low-dose droperidol versus qt-interval monitoring include underlying long-qt interval acute coronary syndrome potential drug-drug interactions steepest t-wave downslope ventricular free wall 5 Ξ±-subunit [lqt3] monitoring qt/qtc intervals unlike high-risk drugs torsades de pointes early-phase clinical testing sudden infant death torsade de pointes exaggerated qt-interval prolongation polymorphic ventricular tachycardia rare lqts-causing mutations independent compound mutations alters liver metabolism macroscopic t-wave alternans license information pmcid clinically recognizable historical
Questions {β}
- How really rare are rare diseases?
- Is gender a risk factor for adverse drug reactions?
- What is the minimal pacing rate that prevents torsades de pointes?
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