
NCBI . NLM . NIH . GOV {
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Title[redir]:
Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex - PMC
Description:
The transcription factor Snail has been described as a direct repressor of E-cadherin expression during development and carcinogenesis; however, the specific mechanisms involved in this process remain largely unknown. Here we show that mammalian ...
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Keywords {🔍}
ecadherin, snail, promoter, cells, hdac, fig, cell, repression, histone, pubmed, google, scholar, doi, activity, tsa, expression, msina, complex, endogenous, antibodies, corepressor, results, assays, mouse, shown, treatment, repressor, proteins, interaction, chip, domain, sin, snailha, carb, analysis, specific, transcriptional, lines, complexes, transcription, gene, analyzed, pmc, control, biol, mdcksnail, hek, performed, cancer, histones,
Topics {✒️}
32-amino-acid n-terminal domain snail-expressing e-cadherin-deficient cells cell-adhesion molecule e-cadherin full-length gst-snail protein independent mdck-gfp-snail clones anti-dimethyl-k4 histone h3 zinc-finger transcription factors short amino-terminal sequence anti-dimethyl-k9 histone h3 pmc beta search e-cadherin germline mutations genome-wide binding map cell-proliferation factor hcf-1 downregulated e-cadherin maintain intact e-cadherin locus de la peña-ingelmo c-terminal binding protein e-cadherin promoter requires protein cross-linking agent proximal e-cadherin promoter e-cadherin promoter sequences full-length snail cdna wild-type mdck cells dimethyl-k4 histone h3 mouse e-cadherin promoter goat anti-rabbit conjugated anti-rabbit fluorescein isothiocyanate mdck-gfp-snail cell lines downregulate e-cadherin expression maintain e-cadherin expression endogenous e-cadherin promoter extra cross-linking step e-cadherin promoter mediated e-cadherin-expressing cells repress e-cadherin promoter α-met-k4-h3 high e-cadherin expression e-cadherin gene expression repressing e-cadherin expression canine e-cadherin promoter sheep anti-mouse-hrp repress e-cadherin expression anti-acetyl-histone h3 sodium dodecyl sulfate-7 e-cadherin promoter repression estrogen receptor-dependent fashion dimethyl-k9 histone h3 e-cadherin promoter induced e-cadherin promoter occurs e-cadherin promoter remains
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