
NCBI . NLM . NIH . GOV {
}
Title[redir]:
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer - PMC
Description:
The EML4-ALK fusion gene has been detected in ~7% of Japanese non-small cell lung cancers (NSCLC). We determined the frequency of EML4-ALK in Caucasian NSCLCs and in NSCLC cell lines. We also determined whether TAE684, a specific ALK kinase ...
Matching Content Categories {π}
- Science
- Education
- Telecommunications
Content Management System {π}
What CMS is ncbi.nlm.nih.gov built with?
Custom-built
No common CMS systems were detected on Ncbi.nlm.nih.gov, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of ncbi.nlm.nih.gov audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Ncbi.nlm.nih.gov Make Money? {πΈ}
We can't tell how the site generates income.
Not all websites are made for profit; some exist to inform or educate users. Or any other reason why people make websites. And this might be the case. Ncbi.nlm.nih.gov might be plotting its profit, but the way they're doing it isn't detectable yet.
Keywords {π}
cell, emlalk, alk, doi, tae, nsclc, lines, cancer, kinase, growth, patients, egfr, fusion, dfci, line, lung, pubmed, google, scholar, gene, tumors, cells, detected, treatment, inhibition, fig, apoptosis, tumor, exon, variant, inhibitor, inhibitors, data, akt, phosphorylation, combination, shown, erlotinib, erk, studies, array, erbb, eml, frozen, probes, significant, effects, gefitinib, pmc, stat,
Topics {βοΈ}
supplementary materials nihms263091-supplement-supplement_1 supplementary material nihms263091-supplement-supplement_1 anaplastic large-cell lymphoma small extra-chromosomal fragment phospho-receptor tyrosine kinase bcr-abl tyrosine kinase small-cell lung cancer anaplastic large-cell lymphomas pmc beta search irreversible pan-erbb inhibitor paraffin embedded slides anti-Ξ±-tubulin antibody c-terminal kinase domain npm-alk mediated lyphomagenesis eml4-alk fusion gene gefitinib-sensitizing egfr mutations eml4-alk fusion signal 25 mg/kg/day dose receptor tyrosine kinases receptor tyrosine kinase eml4-alk fusion genes eml4-alk cell line small-cell lung anaplastic lymphoma kinase tae684 10 mg/kg/day tae684 25 mg/kg/day supplementary materials included hematoxylin/eosin-stained slides human lung carcinomas rneasy mini kit lung cancer jussi detected eml4-alk fusion multiple signaling pathways cytoreductive antitumor activity chemotherapy naΓ―ve female entire kinase domain necrotic tumor tissues small-molecule inhibitor rna isolation kit egfr/erbb2 kinase inhibitor gamma satellite dna natl cancer inst detected eml4-alk significantly lung cancer models samsung medical center small molecule inhibitors small-molecule inhibitors phospho-rtk array comprising 25 mg/kg/day 10 mg/kg/day
Social Networks {π}(6)
External Links {π}(73)
- How much does https://doi.org/10.1158/1078-0432.CCR-08-0168 rake in every month?
- Earnings of http://www.graphpad.com
- How much profit does https://doi.org/10.1126/science.8122112 make?
- How much does https://scholar.google.com/scholar_lookup?journal=Science&title=Fusion%20of%20a%20kinase%20gene,%20ALK,%20to%20a%20nucleolar%20protein%20gene,%20NPM,%20in%20non-Hodgkin%E2%80%99s%20lymphoma&author=SW%20Morris&author=MN%20Kirstein&author=MB%20Valentine&volume=263&publication_year=1994&pages=1281-4&pmid=8122112&doi=10.1126/science.8122112& generate monthly?
- https://doi.org/10.1182/blood-2007-04-060715's total income per month
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Blood&title=Pathobiology%20of%20ALK+%20anaplastic%20large-cell%20lymphoma&author=HM%20Amin&author=R%20Lai&volume=110&publication_year=2007&pages=2259-67&pmid=17519389&doi=10.1182/blood-2007-04-060715& bring in?
- Monthly income for https://doi.org/10.1038/nature05945
- How much does https://scholar.google.com/scholar_lookup?journal=Nature&title=Identification%20of%20the%20transforming%20EML4-ALK%20fusion%20gene%20in%20non-small-cell%20lung%20cancer&author=M%20Soda&author=YL%20Choi&author=M%20Enomoto&volume=448&publication_year=2007&pages=561-6&pmid=17625570&doi=10.1038/nature05945& net monthly?
- What's the monthly money flow for https://doi.org/10.1182/blood-2005-05-2125?
- https://scholar.google.com/scholar_lookup?journal=Blood&title=Ablation%20of%20oncogenic%20ALK%20is%20a%20viable%20therapeutic%20approach%20for%20anaplastic%20large-cell%20lymphomas&author=R%20Piva&author=R%20Chiarle&author=AD%20Manazza&volume=107&publication_year=2006&pages=689-97&pmid=16189272&doi=10.1182/blood-2005-05-2125& income
- How much profit is https://doi.org/10.1002/med.20109 making per month?
- Profit of https://scholar.google.com/scholar_lookup?journal=Med%20Res%20Rev&title=Development%20of%20anaplastic%20lymphoma%20kinase%20(ALK)%20small-molecule%20inhibitors%20for%20cancer%20therapy&author=R%20Li&author=SW%20Morris&publication_year=2007&pmid=17694547&doi=10.1002/med.20109&
- How much does https://doi.org/10.1073/pnas.0609412103 net monthly?
- See how much https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&title=Identification%20of%20NVP-TAE684,%20a%20potent,%20selective,%20and%20efficacious%20inhibitor%20of%20NPM-ALK&author=AV%20Galkin&author=JS%20Melnick&author=S%20Kim&volume=104&publication_year=2007&pages=270-5&pmid=17185414&doi=10.1073/pnas.0609412103& makes per month
- How much money does https://doi.org/10.1158/0008-5472.CAN-06-4443 make?
- https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=An%20orally%20available%20small-molecule%20inhibitor%20of%20c-Met,%20PF-2341066,%20exhibits%20cytoreductive%20antitumor%20efficacy%20through%20antiproliferative%20and%20antiangiogenic%20mechanisms&author=HY%20Zou&author=Q%20Li&author=JH%20Lee&volume=67&publication_year=2007&pages=4408-17&pmid=17483355&doi=10.1158/0008-5472.CAN-06-4443&'s total income per month
- What's https://doi.org/10.1158/1535-7163.MCT-07-0365's gross income?
- How much does https://scholar.google.com/scholar_lookup?journal=Mol%20Cancer%20Ther&title=Cytoreductive%20antitumor%20activity%20of%20PF-2341066,%20a%20novel%20inhibitor%20of%20anaplastic%20lymphoma%20kinase%20and%20c-Met,%20in%20experimental%20models%20of%20anaplastic%20large-cell%20lymphoma&author=JG%20Christensen&author=HY%20Zou&author=ME%20Arango&volume=6&publication_year=2007&pages=3314-22&pmid=18089725&doi=10.1158/1535-7163.MCT-07-0365& earn?
- Learn about the earnings of https://doi.org/10.1073/pnas.191502998
- https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&title=Classification%20of%20human%20lung%20carcinomas%20by%20mRNA%20expression%20profiling%20reveals%20distinct%20adenocarcinoma%20subclasses&author=A%20Bhattacharjee&author=WG%20Richards&author=J%20Staunton&volume=98&publication_year=2001&pages=13790-5&pmid=11707567&doi=10.1073/pnas.191502998&'s total income per month
- https://doi.org/10.1200/JCO.2005.05.1748's total income per month
- Check the income stats for https://scholar.google.com/scholar_lookup?journal=J%20Clin%20Oncol&title=Gene%20expression%20profiling%20reveals%20reproducible%20human%20lung%20adenocarcinoma%20subtypes%20in%20multiple%20independent%20patient%20cohorts&author=DN%20Hayes&author=S%20Monti&author=G%20Parmigiani&volume=24&publication_year=2006&pages=5079-90&pmid=17075127&doi=10.1200/JCO.2005.05.1748&
- How much does https://doi.org/10.1158/0008-5472.CAN-07-1885 net monthly?
- What's the profit of https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=PF00299804,%20an%20irreversible%20pan-ERBB%20inhibitor,%20is%20effective%20in%20lung%20cancer%20models%20with%20EGFR%20and%20ERBB2%20mutations%20that%20are%20resistant%20to%20gefitinib&author=JA%20Engelman&author=K%20Zejnullahu&author=CM%20Gale&volume=67&publication_year=2007&pages=11924-32&pmid=18089823&doi=10.1158/0008-5472.CAN-07-1885&?
- What's the financial outcome of https://doi.org/10.1007/s004120000095?
- How much does https://scholar.google.com/scholar_lookup?journal=Chromosoma&title=Distribution%20of%20gamma%20satellite%20DNA%20on%20the%20human%20X%20and%20Y%20chromosomes%20suggests%20that%20it%20is%20not%20required%20for%20mitotic%20centromere%20function&author=C%20Lee&author=R%20Critcher&author=JG%20Zhang&author=W%20Mills&author=CJ%20Farr&volume=109&publication_year=2000&pages=381-9&pmid=11072793&doi=10.1007/s004120000095& pull in?
- Earnings of https://doi.org/10.1158/0008-5472.CAN-04-1905
- How much does https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=Gefitinib%20induces%20apoptosis%20in%20the%20EGFRL858R%20non-small-cell%20lung%20cancer%20cell%20line%20H3255&author=S%20Tracy&author=T%20Mukohara&author=M%20Hansen&volume=64&publication_year=2004&pages=7241-4&pmid=15492241&doi=10.1158/0008-5472.CAN-04-1905& gross monthly?
- What are the total earnings of https://doi.org/10.1056/NEJMoa050736?
- How much does https://scholar.google.com/scholar_lookup?journal=N%20Engl%20J%20Med&title=Erlotinib%20in%20lung%20cancer%20-%20molecular%20and%20clinical%20predictors%20of%20outcome&author=MS%20Tsao&author=A%20Sakurada&author=JC%20Cutz&volume=353&publication_year=2005&pages=133-44&pmid=16014883&doi=10.1056/NEJMoa050736& gross monthly?
- What's https://doi.org/10.1126/science.1142946's gross income?
- See how much https://scholar.google.com/scholar_lookup?journal=Science&title=Coactivation%20of%20receptor%20tyrosine%20kinases%20affects%20the%20response%20of%20tumor%20cells%20to%20targeted%20therapies&author=JM%20Stommel&author=AC%20Kimmelman&author=H%20Ying&volume=318&publication_year=2007&pages=287-90&pmid=17872411&doi=10.1126/science.1142946& makes per month
- What's the monthly money flow for https://doi.org/10.1056/NEJM200104053441401?
- How much does https://scholar.google.com/scholar_lookup?journal=N%20Engl%20J%20Med&title=Efficacy%20and%20safety%20of%20a%20specific%20inhibitor%20of%20the%20BCR-ABL%20tyrosine%20kinase%20in%20chronic%20myeloid%20leukemia&author=BJ%20Druker&author=M%20Talpaz&author=DJ%20Resta&volume=344&publication_year=2001&pages=1031-7&pmid=11287972&doi=10.1056/NEJM200104053441401& pull in?
- https://doi.org/10.1056/NEJMoa020461 income
- How much does https://scholar.google.com/scholar_lookup?journal=N%20Engl%20J%20Med&title=Efficacy%20and%20safety%20of%20imatinib%20mesylate%20in%20advanced%20gastrointestinal%20stromal%20tumors&author=GD%20Demetri&author=M%20von%20Mehren&author=CD%20Blanke&volume=347&publication_year=2002&pages=472-80&pmid=12181401&doi=10.1056/NEJMoa020461& generate monthly?
- How much money does https://doi.org/10.1200/JCO.2005.05.4692 make?
- What's the profit of https://scholar.google.com/scholar_lookup?journal=J%20Clin%20Oncol&title=Prospective%20phase%20II%20study%20of%20gefitinib%20for%20chemotherapy-naive%20patients%20with%20advanced%20non-small-cell%20lung%20cancer%20with%20epidermal%20growth%20factor%20receptor%20gene%20mutations&author=A%20Inoue&author=T%20Suzuki&author=T%20Fukuhara&volume=24&publication_year=2006&pages=3340-6&pmid=16785471&doi=10.1200/JCO.2005.05.4692&?
- How much does https://doi.org/10.1126/science.1099314 pull in monthly?
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?journal=Science&title=EGFR%20mutations%20in%20lung%20cancer:%20correlation%20with%20clinical%20response%20to%20gefitinib%20therapy&author=JG%20Paez&author=PA%20Janne&author=JC%20Lee&volume=304&publication_year=2004&pages=1497-500&pmid=15118125&doi=10.1126/science.1099314&?
- How much revenue does https://doi.org/10.1159/000086994 generate?
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=Oncology&title=Therapeutic%20targeting%20of%20multiple%20signaling%20pathways%20in%20malignant%20pleural%20mesothelioma&author=T%20Mukohara&author=G%20Civiello&author=BE%20Johnson&author=PA%20Janne&volume=68&publication_year=2005&pages=500-10&pmid=16020981&doi=10.1159/000086994&?
- https://doi.org/10.1002/jcp.10472's financial summary
- Income figures for https://scholar.google.com/scholar_lookup?journal=J%20Cell%20Physiol&title=Anaplastic%20lymphoma%20kinase%20proteins%20in%20growth%20control%20and%20cancer&author=K%20Pulford&author=SW%20Morris&author=F%20Turturro&volume=199&publication_year=2004&pages=330-58&pmid=15095281&doi=10.1002/jcp.10472&
- Profit of https://doi.org/10.3322/canjclin.57.1.43
- What's the revenue for https://scholar.google.com/scholar_lookup?journal=CA%20Cancer%20J%20Clin&title=Cancer%20statistics,%202007&author=A%20Jemal&author=R%20Siegel&author=E%20Ward&volume=57&publication_year=2007&pages=43-66&pmid=17237035&doi=10.3322/canjclin.57.1.43&?
- What's the financial gain of https://doi.org/10.1200/JCO.2005.04.3224?
- https://scholar.google.com/scholar_lookup?journal=J%20Clin%20Oncol&title=Use%20of%20cigarette-smoking%20history%20to%20estimate%20the%20likelihood%20of%20mutations%20in%20epidermal%20growth%20factor%20receptor%20gene%20exons%2019%20and%2021%20in%20lung%20adenocarcinomas&author=D%20Pham&author=MG%20Kris&author=GJ%20Riely&volume=24&publication_year=2006&pages=1700-4&pmid=16505411&doi=10.1200/JCO.2005.04.3224&'s financial summary
- What's the monthly money flow for https://doi.org/10.1126/science.1073096?
- What's the financial intake of https://scholar.google.com/scholar_lookup?journal=Science&title=Cancer.%20Addiction%20to%20oncogenes--the%20Achilles%20heal%20of%20cancer&author=IB%20Weinstein&volume=297&publication_year=2002&pages=63-4&pmid=12098689&doi=10.1126/science.1073096&?
- How much revenue does https://doi.org/10.1126/science.1101637 bring in?
- How much cash flow does https://scholar.google.com/scholar_lookup?journal=Science&title=Gefitinib-sensitizing%20EGFR%20mutations%20in%20lung%20cancer%20activate%20anti-apoptotic%20pathways&author=R%20Sordella&author=DW%20Bell&author=DA%20Haber&author=J%20Settleman&volume=305&publication_year=2004&pages=1163-7&pmid=15284455&doi=10.1126/science.1101637& have monthly?
- Earnings of https://doi.org/10.1038/nm1249
- What's the financial gain of https://scholar.google.com/scholar_lookup?journal=Nat%20Med&title=Stat3%20is%20required%20for%20ALK-mediated%20lymphomagenesis%20and%20provides%20a%20possible%20therapeutic%20target&author=R%20Chiarle&author=WJ%20Simmons&author=H%20Cai&volume=11&publication_year=2005&pages=623-9&pmid=15895073&doi=10.1038/nm1249&?
- How much does https://doi.org/10.1038/sj.onc.1207703 earn?
- What is the earnings of https://scholar.google.com/scholar_lookup?journal=Oncogene&title=Selective%20inhibition%20of%20STAT3%20induces%20apoptosis%20and%20G(1)%20cell%20cycle%20arrest%20in%20ALK-positive%20anaplastic%20large%20cell%20lymphoma&author=HM%20Amin&author=TJ%20McDonnell&author=Y%20Ma&volume=23&publication_year=2004&pages=5426-34&pmid=15184887&doi=10.1038/sj.onc.1207703&?
- What's the income generated by https://doi.org/10.1093/jnci/dji238 each month?
- https://scholar.google.com/scholar_lookup?journal=J%20Natl%20Cancer%20Inst&title=Differential%20effects%20of%20gefitinib%20and%20cetuximab%20on%20non-small-cell%20lung%20cancers%20bearing%20epidermal%20growth%20factor%20receptor%20mutations&author=T%20Mukohara&author=JA%20Engelman&author=NH%20Hanna&volume=97&publication_year=2005&pages=1185-94&pmid=16106023&doi=10.1093/jnci/dji238&'s total income per month
- What's the monthly income of https://scholar.google.com/scholar_lookup?journal=Cancer%20Res&title=Aberrant%20epidermal%20growth%20factor%20receptor%20signaling%20and%20enhanced%20sensitivity%20to%20EGFR%20inhibitors%20in%20lung%20cancer&author=J%20Amann&author=S%20Kalyankrishna&author=PP%20Massion&volume=65&publication_year=2005&pages=226-35&pmid=15665299&?
- See how much https://doi.org/10.1016/j.cell.2007.11.025 makes per month
- How much does https://scholar.google.com/scholar_lookup?journal=Cell&title=Global%20survey%20of%20phosphotyrosine%20signaling%20identifies%20oncogenic%20kinases%20in%20lung%20cancer&author=K%20Rikova&author=A%20Guo&author=Q%20Zeng&volume=131&publication_year=2007&pages=1190-203&pmid=18083107&doi=10.1016/j.cell.2007.11.025& generate monthly?
- What's the income of https://github.com/ncbi?
- How much does https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323 generate monthly?
- What is the monthly revenue of https://www.nlm.nih.gov/web_policies.html?
- https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office income
- How profitable is https://www.hhs.gov/vulnerability-disclosure-policy/index.html?
- How much income is https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Amanuscript earning monthly?
- What is the monthly revenue of https://www.nlm.nih.gov/accessibility.html?
- What's the profit of https://www.nlm.nih.gov/careers/careers.html?
- Get to know what's the income of https://www.nlm.nih.gov/
- What is the monthly revenue of https://www.nih.gov/?
- Discover the revenue of https://www.hhs.gov/
- How much does https://www.usa.gov/ net monthly?
Analytics and Tracking {π}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {π}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {π¦}
- Ncbi