
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment - PMC
Description:
In several murine models of autoimmune arthritis, Th17 cells are the dominant initiators of inflammation. In human arthritis the majority of IL-17–secreting cells within the joint express a cytokine phenotype intermediate between Th17 and Th1. Here ...
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Keywords {🔍}
cells, doi, expression, arthritis, pubmed, google, scholar, synovial, fig, ifnγ, human, joint, populations, pmc, article, phenotype, rorc, patients, sorted, plasticity, free, population, site, vitro, inflamed, receptor, sfmc, immunol, cytokine, tgfβ, ccr, flow, cell, jia, enriched, disease, blood, show, vivo, shown, data, autoimmune, inflammatory, joints, control, detected, presence, levels, tcell, tcr,
Topics {✒️}
ifn-γ-specific capture assays pmc beta search anti-apoptotic bcl-xl live/dead discriminant dye topo-ta cloning strategy cd8+ t-cell expansions org/lookup/suppl/doi nod/scid recipient mice aryl hydrocarbon receptor t-cell receptor analysis human t-cell expansion t-cell receptor bv t-bet mrna expression tcr-β variable chain recombinant human ifn-γ capture cytokine-expressing cells patients coexpress ifn-γ cells coexpressing ifn-γ ifn-γ protein detected analyzed t-cell receptor cd161-ifn-γ+ populations cytokine-expressing synovial cd4+ regulate ifn-γ production th1 cytokine ifn-γ ifn-γ–secreting cd4+ direct submission article il-23r mrna expression proinflammatory th1/th0 cells cell contact-dependent mechanism serum-free medium platelet-depleted synovial supernatants transcription factor expression supporting information online pure il-17–secreting lineage cell il-6r expression ccr6-expressing th17 cells significantly higher levels full tcr sequences cytokine-producing cells gated full informed consent ifn-γ express sfmc il-23r expression th1 oligoclonal patterns coexpressing ifn-γ th17-mediated disease license information pmcid t-bet expression showing cd161 expression regulate ifn-γ express chemokine receptors
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- What's the financial outcome of https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323?
- Get to know https://www.nlm.nih.gov/web_policies.html's earnings
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- Learn how profitable https://www.usa.gov/ is on a monthly basis
Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Prism.js
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi