
NCBI . NLM . NIH . GOV {
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Title[redir]:
Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression - PMC
Description:
Breast cancer is the most common cancer among women, and despite significant advances in diagnosing and treating it, metastatic spread of cancer cells results in a high mortality rate. Epithelial-to-mesenchymal transition (EMT) is an embryonic ...
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Keywords {π}
doi, cancer, cells, breast, pubmed, google, scholar, snail, cell, emt, twist, expression, pmc, article, tumour, free, epithelial, metastasis, mammary, stem, transition, factors, transcription, tumours, development, role, human, zeb, progression, markers, ecadherin, family, genes, cancers, gene, biol, res, epithelialmesenchymal, gland, basallike, growth, phenotype, receptor, nat, invasion, snai, factor, carcinoma, resistance, features,
Topics {βοΈ}
hypoxia-inducible factor-1-dependent repression pmc beta search tgf-beta induced transdifferentiation basic helixloop-helix factors carg box-binding factor basic helixloop-helix proteins transforming growth factor-beta trkb-induced epithelial-mesenchymal transition v12h-ras-transformed hmles zinc-finger transcription factors ras oncogene-induced senescence her2/neu-transformed hmles y-box transcription factor smad-binding element nearby integrated genomic-proteomic approach pro-metastatic gene rhoc greater mammosphere-forming ability e-cadherin repressors participate hif-1alpha promotes metastasis tumour necrosis factor-alpha cd44+/cd24- cells showed [doi] [pubmed] kreike ligand-activated erΞ± forms cd44+/cd24- expression pattern claudin-low tumor cells zinc-finger protein slug regulates e-cadherin triple-negative breast cancers mi-2/nurd complex subunit tgf-Ξ²-induced emt secrete pro-inflammatory cytokines references thiery jp twist-snail axis critical enriched cd44+/cd24- cells heterogeneous e-cadherin expression tgf-Ξ² induces hmga2 e-cadherin repressors zeb1 epithelial-mesenchymal transition markers cd44+/cd24-/low phenotype license information pmcid represses nf-kappab activity inflammation-induced cell migration breast cancer-related therapies tumour micro-environment snail1 epithelial-mesenchymal transition phenotype therapy-resistant cell populations breast cancer relates hif-mediated regulation klein-szanto aj e-box motifs
Questions {β}
- How basal are triple-negative breast cancers?
- Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
- Snail1 and Twist1 as criteria in breast cancer classification?
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- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=Nat%20Cell%20Biol&title=The%20miR-200%20family%20and%20miR-205%20regulate%20epithelial%20to%20mesenchymal%20transition%20by%20targeting%20ZEB1%20and%20SIP1&author=PA%20Gregory&author=AG%20Bert&author=EL%20Paterson&author=SC%20Barry&author=A%20Tsykin&volume=10&publication_year=2008&pages=593-601&pmid=18376396&doi=10.1038/ncb1722&
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- Find out how much https://doi.org/10.1016/j.cell.2005.08.020 earns monthly
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