
NCBI . NLM . NIH . GOV {
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Title[redir]:
Endogenous nâ3 fatty acids protect ovariectomy induced bone loss by attenuating osteoclastogenesis - PMC
Description:
Beneficial effects of nâ3 fatty acids (FA) on bone mineral density (BMD) have been reported in mice, rats and human beings, but the precise mechanisms involved have not been described. This study used the Fatâ1 mouse, a transgenic model that ...
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Keywords {đ}
mice, bone, fat, google, scholar, pubmed, doi, cells, fatty, acids, ovx, loss, nitric, oxide, endogenous, bmd, nfÎșb, acid, production, effect, activation, transgenic, sham, lower, osteoclastogenesis, compared, cytokines, osteoporosis, ratio, osteoclast, pmc, significantly, diet, activity, resorption, usa, significant, higher, marrow, inflammatory, health, study, coxii, free, iÎșbα, article, analysed, level, serum, res,
Topics {âïž}
lpsâstimulated coxâii activity aaâderived proâinflammatory mediators proâinflammatory cytokines tnfâα macrophage colonyâstimulating factor antiâosteoclastogenic antiâinflammatory cytokines decrease endotoxinâinduced activation nfâÎșbâdna binding tartrateâresistant acid phosphatase lpsâstimulated bone marrow coxâii stimulates osteoclastogenesis tumour necrosis factorâα lpsâtreated bm cells proâinflammatory cytokine levels ïżœregulate coxâii expression fatâ1âtransgenic littermates born ovxâinduced bone loss nfâÎșb p50 subunits p50 nfâÎșb subunits pmc beta search osteoclastogenic proâinflammatory cytokines ovxâinduced bmd loss antiâosteoclastogenic mechanism exerted mice lacking nfâkappab1 coxâii reducing ability proâinflammatory cytokines production ïżœregulate coxâii activity tumor necrosis factor ranklâinduced interferonâbeta alphaâlinolenic acid antiânfâÎșb antibody ranklâstimulated osteoclast formation nitric oxide synthase prevent postâmenopausal osteoporosis nfâÎșb developed osteopetrosis lower activation nfâÎșb nfâÎșb signalling pathway pmc copyright notice mouse free soluble lpsâstimulated activation lps stimulated activation omegaâ3 fatty acid transcription factor assays vital transcription factor activated p65 nfâÎșb omegaâ3 fatty acids preventing nfâkappab activation osteoclast boneâresorption activity piâÎșbâα/total tumour necrosis factor lpsâstimulated production
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Analytics and Tracking {đ}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {đ}
- jQuery
- jQuery module (jquery-3.6.0)
- Particles.js
Emails and Hosting {âïž}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {đŠ}
- Ncbi