
NCBI . NLM . NIH . GOV {
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Title[redir]:
Regulation of Membrane-Type 4 Matrix Metalloproteinase by SLUG Contributes to Hypoxia-Mediated Metastasis - PMC
Description:
The hypoxic tumor environment has been shown to be critical to cancer metastasis through the promotion of angiogenesis, induction of epithelial-mesenchymal transition (EMT), and acquisition of invasive potential. However, the impact of hypoxia on ...
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Keywords {🔍}
mtmmp, cells, doi, cancer, expression, slug, hifα, cell, figure, tumor, metastasis, hypoxia, pubmed, google, scholar, invasiveness, control, promoter, mtluc, versus, overexpression, analysis, human, activation, factor, sas, sascdna, results, emt, performed, snail, mmp, sashifαδodd, clones, pmc, matrix, western, blot, hnscc, protein, article, growth, assays, levels, twist, generated, sirna, antibody, shown, pulmonary,
Topics {✒️}
short-interference rna-mediated knockdown o2-dependent degradation domain oxygen degradation domain short-interference rna experiment glycosyl-phosphatidyl inositol-anchored protease short-interference rna quantitative real-time rt-pcr hypoxia/hif-1α-induced mt4-mmp expression membrane-type matrix metalloproteinase sas-slug-si-mt4-mmp injections hypoxia-inducible factor-1-dependent repression real-time rt-pcr analysis hif-1α-induced mt4-mmp transactivation sas-mt4-mmp versus sas-cdna3 hif-1α-induced mt4-mmp expression hif-1α/mt4-mmp coexpression versus hypoxia/hif-1α-mediated cancer invasiveness hif-1α/mt4-mmp ihc result hif-1α-mediated mt4-mmp induction si-scr/sas-slug-si-scr e-box-binding transcriptional factor commercialized anti-mt4-mmp antibody hif-1α-induced mt4-mmp zinc-finger transcriptional factor membrane-anchored matrix metalloproteinases sas-slug versus sas-cdna3 hif-1α-induced transcriptional activation snail-induced mesenchymal transition matrix metalloproteinase-2 [mmp-2] matrix metalloproteinase-2 expression mice receiving sas-cdna3 e-cadherin-driven reporter constructs plasmid psuper-hif-1α-si squamous cell carcinomas hypoxia-inducible factor-1α hypoxia-inducible factor 1α epithelial-mesenchymal transition mt4-mmp-overexpressing 293t cells hif-1α/mt4-mmp coexpression sas-slug-si-mt4-mmp human breast carcinoma regulates mt4-mmp expression bacterial β-galactosidase gene epithelial marker e-cadherin hif-1α mutant harboring inactive hif-1α mutant induced mt4-mmp expression mt4-mmp significantly promoted anti-hif-1α antibody mesenchymal marker n-cadherin
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- How much revenue does https://doi.org/10.1038/nrc1821 bring in?
- What's https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Cancer&title=Tumour%20microenvironment%E2%80%94opinion:%20validating%20matrix%20metalloproteinases%20as%20drug%20targets%20and%20anti-targets%20for%20cancer%20therapy&author=CM%20Overall&author=O%20Kleifeld&volume=6&publication_year=2006&pages=227-239&pmid=16498445&doi=10.1038/nrc1821&'s gross income?
- How much profit does https://github.com/ncbi generate?
- https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/%4038.9959508, -77.101021,17z/data%3D!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb%3A0x19156f88b27635b8!8m2!3d38.9959508! 4d-77.0988323 income
- How much does https://www.nlm.nih.gov/web_policies.html generate monthly?
- What's the total monthly financial gain of https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office?
- How much does https://www.hhs.gov/vulnerability-disclosure-policy/index.html generate monthly?
- How much money does https://support.nlm.nih.gov/?pagename=cloudpmc-viewer%3Apmc%3Aarticle%3Ajournal make?
- How much does https://www.nlm.nih.gov/accessibility.html net monthly?
- Monthly income for https://www.nlm.nih.gov/careers/careers.html
- How much money does https://www.nlm.nih.gov/ generate?
- Monthly income for https://www.nih.gov/
- Earnings of https://www.hhs.gov/
- How much profit does https://www.usa.gov/ make?
Analytics and Tracking {📊}
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- jQuery
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Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
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