
NCBI . NLM . NIH . GOV {
}
Title[redir]:
The epithelial-mesenchymal transition generates cells with properties of stem cells - PMC
Description:
The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer invasion and metastasis. Induction of an EMT in immortalized human mammary epithelial cells (HMLEs) results in the acquisition of ...
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Keywords {🔍}
cells, doi, emt, mammary, stem, figure, cdhighcdlow, epithelial, expression, cdlowcdhigh, pubmed, google, scholar, cancer, cell, human, mammospheres, twist, supplementary, snail, normal, fold, markers, hmle, breast, culture, transcription, pmc, similar, tamoxifen, tumor, ecadherin, data, population, form, increased, isolated, undergone, formed, levels, mouse, tumors, neoplastic, vimentin, primary, article, ability, tissues, factors, mrnas,
Topics {✒️}
cleared mammary fat-pads cd49fhigh/cd24med-depleted cells failed cd49fhigh/cd24med-depleted population failed mesenchymal-appearing cd44high/cd24low cells real-time rt-pcr human colon-cancer-initiating cells k18/k14 double-positive cells k14/k18 double-positive cells mammosphere-forming cd44high/cd24low cells mammosphere-forming cd44low/cd24high cells facs-purified cd44high/cd24low cells cd49fhigh/cd24med-depleted cells mammary gland-repopulating cells cd49fhigh/cd24med-depleted populations bi-potential progenitor cells antibody-coupled beads specific pmc beta search hmle-snail-er cells acquired hmle-twist-er cells developed rt-pcr analyses revealed emt/stem-cell state depends single-cell clones derived cd44high/cd24low cells possess cd44high/cd24low cells resembled cd44high/cd24low cells exist mesenchymal-appearing cells generated cd49f/integrin α6-positive sorted cd44low/cd24high cells purifying single-cell clones cd44high/cd24low antigen phenotype cd44high/cd24low hmle cells sorted cd44low/cd24high population cd44high/cd24low antigenic phenotype cd44high/cd24low cells isolated cd44high/cd24low cells developed /cd44high/cd24low cells isolated isolated cd44high/cd24low cells cd44high/cd24low marker phenotype cancer stem cells--perspectives initially isolated cd44high/cd24low cd44high/cd24low cells exhibited continuous emt-inducing signals bi-potential precursor cells cd44low/cd24high cells expressed cd44high/cd24low cells behave clonal cd44low/cd24high population mammosphere-forming cells isolated gland-reconstituting stem cells emt-inducing transcription factors single mammosphere-forming cell
Questions {❓}
- Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
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Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
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Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
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Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
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- lhcns1.nlm.nih.gov
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CDN Services {📦}
- Ncbi