
NCBI . NLM . NIH . GOV {
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Title[redir]:
Molecular Profiling of Breast Cancer Cell Lines Defines Relevant Tumor Models and Provides a Resource for Cancer Gene Discovery - PMC
Description:
Breast cancer cell lines have been used widely to investigate breast cancer pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease, and it is important to understand how well and which cell lines best model that ...
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Keywords {🔍}
doi, cell, cancer, breast, hcc, lines, pubmed, google, scholar, expression, genes, gene, luminal, tumors, dna, cells, line, erbb, pmc, tumor, subtype, analysis, subtypes, human, article, free, mda, sum, basallike, data, genomic, basala, copy, number, basal, res, fig, profiles, corf, cnas, brca, table, molecular, basalb, epithelial, pcr, transcriptional, signature, profiling, stem,
Topics {✒️}
mitogen-activated protein kinase real-time quantitative pcr stem/progenitor cell compartments mouse monoclonal anti-er-α pmc beta search adaptor protein tks5/fish high-level dna amplifications stem/progenitor-cell characteristics low-level gain/loss peroxidase-labeled anti-mouse atr-mediated checkpoint signaling identify gene-expression subtypes high-level dna amplification white cross-hatched boxes ilc = invasive lobular carcinoma mouse monoclonal anti-actin erk2-elk1 signaling pathway concomitantly altered gene-expression amino-allyl coupling protocol chromosome segment gain/loss mouse monoclonal anti-her2 meet quality-control inspection highly invasive/metastatic lines apip-induced sustained activation muc−/calla+ phenotypes characteristic p53-deficient cells rely tumor gene-expression subtype rabbit monoclonal anti-egfr characteristic gene-expression patterns urokinase-type plasminogen activation bipotent progenitor cells gene-targeted mice deficient multi-molecular signaling complex stem/progenitor cells high-level amplification contained deficient dsb repair idc = invasive ductal carcinoma full malignant phenotype stem/progenitor subpopulation sample labeling/hybridization methods publisher site pdf mammary stem cells cd44+/cd24−/low high-amplitude amplifications rt2 pcr array bipotent basal/luminal progenitors er-positive cancer lines er-positive cell lines identified molecular subtypes–luminal license information pmcid
Questions {❓}
- Cancer ‘stem’ cells and CD133: what's in the name?
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