
NCBI . NLM . NIH . GOV {
}
Title[redir]:
A phase II trial of the vitamin D analogue Seocalcitol (EB1089) in patients with inoperable pancreatic cancer - PMC
Description:
Inoperable cancer of the exocrine pancreas responds poorly to most conventional anti-cancer agents, and new agents are required to palliate this disease. Seocalcitol (EB1089), a vitamin D analogue, can inhibit growth, induce differentiation and ...
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Keywords {🔍}
patients, cancer, google, scholar, pubmed, doi, seocalcitol, disease, study, pancreatic, treatment, dose, patient, weeks, calcium, phase, vitamin, hypercalcaemia, therapy, pmc, serum, advanced, pancreas, survival, toxicity, response, days, chemotherapy, individual, article, vitro, vivo, stable, cells, analogue, growth, objective, free, cell, received, clinical, progression, breast, mtd, nlm, trial, inoperable, efficacy, prior, time,
Topics {✒️}
9-cis-retinoic acid pmc beta search phase ii trial tumour cell-induced angiogenesis serum albumin-corrected calcium albumin-corrected serum calcium inhibiting tumour-induced angiogenesis phase ii trials phase ii study subsequently post-mortem confirmed conventional anti-cancer agents higher anti-tumour activity leukaemic cell lines beatson oncology centre toxicity criteria invest objective anti-tumour activity pancreatic cancer cells anticipated dose-dependent hypercalcaemia 25-dihydroxyvitamin d3 receptor cancer cell lines publisher site pdf breast cancer cells advanced pancreas cancer continuous-infusion 5-fluorouracil advanced pancreatic cancer prostate cancer metastasis serum calcium corrected inoperable pancreatic cancer human breast cancer fasting serum calcium pancreatic cancer xenografts pancreatic cancer made anti-cancer therapy full blood count d-binding protein anti-proliferative effects pancreas responds poorly pmc disclaimer demonstrable biological effect colorectal cancer br license information pmcid objective response rates swog criteria occurred 25′-dihydroxyvitamin d3 inhibits dose-finding phase vitro liver metabolites anti-tumour activity serum calcium values dietary calcium intake clinical disease-related deterioration
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