DOI . ORG {
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Title[redir]:
Southwest Oncology Group standard response criteria, endpoint definitions and toxicity criteria | Investigational New Drugs
Description:
The Southwest Oncology Group, in cooperation with the National Cancer Institute and the other major cooperative oncology groups, has participated in the development of new toxicity criteria for reporting the results of cancer clinical trials. The new criteria (NCI Common Toxicity Criteria) respond to a recognized need to: (1) report toxicities consistently among cooperative groups, particularly for shared ‘intergroup’ clinical trials; (2) strive for comparability in toxicity reporting among clinical trials; and (3) recognize new toxicities accompanying new classes of anticancer treatment modalities. The Southwest Oncology Group has extended the toxicity criteria, incorporating additional new criteria for biological agents, radiation therapy, surgery, and hormonal agents. In addition, endpoint definitions and response criteria are discussed. These have been developed in response to previous uncertainties in clinical trials objectives, to limitations in the resolution of imaging methods, and to demands for greater rigor in response and endpoint definitions. Toxicity criteria, endpoint definitions, and response criteria are tabulated.
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Keywords {🔍}
criteria, oncology, article, response, toxicity, group, clinical, trials, privacy, cookies, content, southwest, endpoint, definitions, cancer, publish, search, access, chapter, data, information, log, journal, research, drugs, green, weiss, cooperative, portfolio, discover, usa, springer, optional, personal, parties, standards, policy, find, track, investigational, standard, cite, stephanie, geoffrey, explore, groups, reporting, toxicities, treatment, agents,
Topics {✒️}
cancer clinical trials month download article/chapter southwest oncology group national cancer institute clinical trials objectives related subjects medical oncology privacy choices/manage cookies clinical trials toxicity criteria published treatment response assessment full article pdf varying standards european economic area anticancer treatment modalities conditions privacy policy report toxicities consistently cooperative groups accepting optional cookies response criteria article green journal finder publish toxicity criteria check access instant access article investigational weiss rights usa geoffrey privacy policy article log personal data drugs aims books a optional cookies information manage preferences toxicity reporting article cite subscription content similar content data protection essential cookies cookies skip toxicities accompanying institution subscribe journal publish response usage analysis social media endpoint definitions
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headline:Southwest Oncology Group standard response criteria, endpoint definitions and toxicity criteria
description:The Southwest Oncology Group, in cooperation with the National Cancer Institute and the other major cooperative oncology groups, has participated in the development of new toxicity criteria for reporting the results of cancer clinical trials. The new criteria (NCI Common Toxicity Criteria) respond to a recognized need to: (1) report toxicities consistently among cooperative groups, particularly for shared ‘intergroup’ clinical trials; (2) strive for comparability in toxicity reporting among clinical trials; and (3) recognize new toxicities accompanying new classes of anticancer treatment modalities. The Southwest Oncology Group has extended the toxicity criteria, incorporating additional new criteria for biological agents, radiation therapy, surgery, and hormonal agents. In addition, endpoint definitions and response criteria are discussed. These have been developed in response to previous uncertainties in clinical trials objectives, to limitations in the resolution of imaging methods, and to demands for greater rigor in response and endpoint definitions. Toxicity criteria, endpoint definitions, and response criteria are tabulated.
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headline:Southwest Oncology Group standard response criteria, endpoint definitions and toxicity criteria
description:The Southwest Oncology Group, in cooperation with the National Cancer Institute and the other major cooperative oncology groups, has participated in the development of new toxicity criteria for reporting the results of cancer clinical trials. The new criteria (NCI Common Toxicity Criteria) respond to a recognized need to: (1) report toxicities consistently among cooperative groups, particularly for shared ‘intergroup’ clinical trials; (2) strive for comparability in toxicity reporting among clinical trials; and (3) recognize new toxicities accompanying new classes of anticancer treatment modalities. The Southwest Oncology Group has extended the toxicity criteria, incorporating additional new criteria for biological agents, radiation therapy, surgery, and hormonal agents. In addition, endpoint definitions and response criteria are discussed. These have been developed in response to previous uncertainties in clinical trials objectives, to limitations in the resolution of imaging methods, and to demands for greater rigor in response and endpoint definitions. Toxicity criteria, endpoint definitions, and response criteria are tabulated.
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