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Title[redir]:
The power to reduce: pyridine nucleotides – small molecules with a multitude of functions - PMC
Description:
The pyridine nucleotides NAD and NADP play vital roles in metabolic conversions as signal transducers and in cellular defence systems. Both coenzymes participate as electron carriers in energy transduction and biosynthetic processes. Their oxidized ...
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Keywords {🔍}
doi, google, scholar, pubmed, nadk, nad, nadp, nadph, free, activity, pmc, yeast, kinase, biol, nadks, article, cells, cell, dehydrogenase, mitochondrial, enzyme, protein, oxidative, cellular, chem, biochem, redox, gene, human, enzymes, cytosolic, acid, stress, state, nadh, figure, substrate, adpribose, gpd, activities, important, signalling, generation, role, cerevisiae, reduced, phosphate, properties, synthesis, plants,
Topics {✒️}
β-nad+-dependent histone/protein deacetylases intracellular adp-ribosyl cyclase/nad+-glycohydrolase glucose-6-phosphate dehydrogenase-deficient erythrocytes 4-hydroxy-2-nonenal-induced oxidative damage cd38/nad+/cyclic adp-ribose system free-flow electrophoretic separations free nicotinamide-adenine dinucleotide encoding glucose-6-phosphate dehydrogenase poly-adp-ribose date back glucose-6-phosphate dehydrogenase variants glucose-6-phosphate dehydrogenase plays molluscan egg-specific nadase nadp+-dependent isocitrate dehydrogenase bound glucose-6-phosphate dehydrogenase nadp-specific isocitrate dehydrogenase glucose-6-phosphate dehydrogenase activity nad+-dependent histone deacetylase pentose-phosphate pathway results na–adenine dinucleotide phosphate nadp-dependent isocitrate dehydrogenases human ki67 fork-head preiss–handler independent route position-specific gap penalties calcium-mobilizing agent derived 2′-specific ca2+-dependent phosphatase pmc beta search polar amino acid nad-dependent histone deacetylation o-acetyl adp-ribose 1-o-acetyl-adp-ribose 3′-o-acetyl-adp-ribose o-acetyl-adp-ribose platelet-derived growth factor nad+-dependent protein deacetylases ube4b/nmnat chimeric gene high gsh/gssg ratio d'adda di fagagna adp-ribosyl cyclases generate mitochondrial pyruvate–malate shuttle adp-ribose moiety undergoes specific isocitrate dehydrogenase n-terminal domain resembles c-terminal domain adopts euglena gracilis klebs glucose-6-phosphate dehydrogenase amino acid residues single nadph-regenerating system variable n-terminal parts represent mono-adp-ribosyltransferases [14 2′-phospho-cyclic adp-ribose
Questions {❓}
- How do poly(P)/ATP–NADKs distinguish between the phosphoryl donors poly(P) and ATP and which amino acid residues determine the difference?
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