
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Characterization of a Bone Morphogenetic Protein-responsive Smad-binding Element - PMC
Description:
Bone morphogenetic proteins (BMPs) are pleiotropic growth and differentiation factors belonging to the transforming growth factor-β (TGF-β) superfamily. Signals of the TGF-β-like ligands are propagated to the nucleus through specific interaction of ...
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Keywords {🔍}
smad, doi, motif, bmp, gccg, cells, binding, pubmed, google, scholar, stimulation, reporter, proteins, dna, tgfβ, smads, figure, genes, cell, bind, sequence, mad, gene, dnabinding, receptors, type, activity, xgccg, xgccglux, pmc, signaling, gel, presence, copies, directly, xmut, probe, luciferase, identified, domain, free, kawabata, drosophila, sequences, reporters, article, mutant, assay, bone, activin,
Topics {✒️}
tgf-β-responsive smad-binding site mediate tgf-β-induced transcription transforming growth factor-β ten ng/ml tgf-β tgf-β-induced transcriptional activation pmc beta search sequence-specific dna-binding proteins serine/threonine kinase activity short amino-acid sequence glutathione-sepharose 4b beads gst-smad fusion proteins tgfβ-inducible transcriptional complexes serine/threonine kinase receptors c-jun/c-fos antibodies caused super-supershift tgf-β signal transduction hetero-oligomeric smad complexes gc-rich sequences distinct stable dna-binding complex tgf-β responsive genes tgf-β-responsive genes cell type-independent manner transmit activin/tgfβ signals homeobox dna-binding proteins dna-binding complex appeared bmps induce bone tgf-β-responsive reporters bone morphogenetic proteins sequence-specific transcription activators bone morphogenetic protein-4 tumor suppressor smad4/dpc4 smad4/dpc4 tumor suppressor tripartite dna-binding sites /pth-related peptide receptor α-minimal essential medium consensus mad-binding site differentiation-dependent gene expression license information pmcid major dna-binding complex stat3-smad1 complex bridged gel shift assay bmp-stimulated r-smads smad binding element mammalian r-smads regulated natural bmp-responsive reporter gst fusion proteins macías-silva dna-binding complexes detected transcriptional adaptor cbp/p300 early embryonal death
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