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Title[redir]:
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies - PMC
Description:
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate tumor suppressor mechanism and participates in the biological processes ...
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Keywords {π}
ferroptosis, doi, pubmed, google, scholar, cancer, cells, free, pmc, article, cell, tumor, gpx, lipid, iron, death, peroxidation, biol, resistance, slca, protein, inhibition, nct, nat, promotes, antitumor, ferroptotic, immune, mitochondrial, role, pathway, acid, inhibiting, mechanisms, res, growth, lung, inhibits, expression, nature, therapy, treatment, stress, mol, induces, tumors, metabolism, suppression, signaling, tme,
Topics {βοΈ}
lncrna h19/mir-19b-3p/fth1 axis downstream raf/mek/mapk axis braf b-raf proto-oncogene 1-steaoryl-2-15-hpete-sn-glycero-3-phosphatidylethanolamine pre-menopausal african-american women secrete exosome-derived mir-3173-5p ras/braf/mek/mapk pathway e-cad e-cadherin anti-pd-1/pd-l1 antibodies voltage-dependent anion channel iron-based metal-organic framework Ξ±-kg Ξ±-ketoglutaric acid pi3k/akt/mtor signaling pathway ppargc1a/bambi/acsl5 axis cystine-glutamate antiporter-dependent manner injectable dextran-chitosan hydrogel restraining nrf2/keap1/xct signaling cell-mediated anti-tumor immunity mtorc1/srebp1/scd5 signaling pathway d-lactate-induced ferroptosis resistance oncogenic-ras-harboring cancer cells oxidized low-density lipoproteins ferroptosis-mediated anti-tumor surveillance cyclic gmp-amp synthase single-cell rna sequencing gpx4-se-sg undergoes conversion protamine thiol cross-linking ampk/acc-mediated pufa inhibition pmc beta search cul3-based e3 ligase nrf2/fsp1 anti-ferroptosis axis specifically recognizing stearoyl-aa-pe triple-negative breast cancer cd36-mediated ferroptosis hampers atp-binding cassette b8 bax/bcl2/vdac2/3 axis cysteine starvation-induced ferroptosis160 261 glutamine-fructose-6-phosphate transaminase amino-terminal neh2 domain dihomo-gamma-linolenic acid african-centric s47 variant ferroptosis-mediated tumor-suppression function n-myristylation-dependent recruitment p53-dependent metabolic remodelling proinflammatory cytokine il-1Ξ² p62-keap1-nrf2 pathway protects regulating cell density-mediated d-lactate-induced ferroptosis limit rsl3/fin56-induced ferroptosis aif-mediated cell death
Questions {β}
- Autophagy and Ferroptosis - Whatβs the connection?
- Ferroptosis, a new pathogenetic mechanism in cardiometabolic diseases and cancer: Is there a role for statin therapy?
- Interferon-gamma: teammate or opponent in the tumour microenvironment?
- Unsolved mysteries: How does lipid peroxidation cause ferroptosis?
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- How much revenue does https://doi.org/10.1038/s41418-020-00691-x generate?
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- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?Cancer%20Genome%20Atlas%20Research,%20N.%20Comprehensive%20genomic%20characterization%20of%20squamous%20cell%20lung%20cancers.%20Nature489,%20519%E2%80%93525%20(2012).%2010.1038/nature11404?
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- How much profit does https://scholar.google.com/scholar_lookup?Estrela,%20J.%20M.%20et%20al.%20Glutathione%20in%20metastases:%20From%20mechanisms%20to%20clinical%20applications.%20Crit.%20Rev.%20Clin.%20Lab.%20Sci.53,%20253%E2%80%93267%20(2016).%2010.3109/10408363.2015.1136259 make?
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