
NCBI . NLM . NIH . GOV {
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Title[redir]:
Epigallocatechin-3-Gallate Alleviates Liver Oxidative Damage Caused by Iron Overload in Mice through Inhibiting Ferroptosis - PMC
Description:
Ferroptosis, a form of regulated cell death, has been widely explored as a novel target for the treatment of diseases. The failure of the antioxidant system can induce ferroptosis. Epigallocatechin-3-Gallate (EGCG) is a natural antioxidant in tea; ...
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Keywords {🔍}
iron, doi, egcg, google, scholar, pubmed, liver, overload, ferroptosis, mice, figure, free, pmc, expression, article, oxidative, cell, damage, caused, antioxidant, addition, mouse, results, serum, protein, slca, levels, increased, lipid, group, ros, cells, tea, anemia, effect, body, weight, data, death, gpx, metabolism, significantly, content, homeostasis, stress, study, mrna, epigallocatechin, gallate, epigallocatechingallate,
Topics {✒️}
informed consent statement epigallocatechin-3-gallatep-rreventsn-methyl-4-phenyl-1 data availability statement 5000 mg/kg feso4 pmc beta search age-related oxidative damage 6-tetrahydropyridine-induced dopaminergic neurodegeneration tab supplementary materials writing—original draft preparation iron metabolism-related gene blood cell-related diseases secondary goat anti-mouse sirt1/foxo1 signaling pathway anti-rabbit antibodies conjugated iron overload-induced ferroptosis c57bl/6j male mice impair nonhaem-iron absorption chronic lymphocytic leukemia inflammatory factors il-1β abnormal ast/alt ratios proinflammatory factors il-1β supplementary materials included iron-dependent death depends attenuating ferroptosis-related diseases institutional animal care green tea epigallocatechin-3-gallate epigallocatechin-3-gallate induces apoptosis data availability statements free iron accumulates reduced serum gsh/gssg lipid-based food systems normal c57bl/6j mice publisher site pdf proinflammatory cytokines il-1β supplementary materials click red blood cells excess free iron eliminate free radicals abbreviations rbc insulin signaling pathway iron-overload mice model funding statement glutathione il-1β/il-6 oxidative injury disappeared durable molecular remission liver gsh/gssg ratio dmem culture medium hamp1-fpn regulatory axis lps-induced raw 264 body weight loss
Questions {❓}
- Autophagy and ferroptosis—What is the connection?
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