
PMC . NCBI . NLM . NIH . GOV {
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Title:
Intestinal Microbiota as an Alternative Therapeutic Target for Epilepsy - PMC
Description:
Epilepsy is one of the most widespread serious neurological disorders, and an aetiological explanation has not been fully identified. In recent decades, a growing body of evidence has highlighted the influential role of autoimmune mechanisms in the ...
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Keywords {🔍}
doi, epilepsy, pubmed, google, scholar, microbiota, autoimmune, pmc, article, intestinal, immune, free, cells, role, diseases, gut, system, cell, disease, responses, patients, journal, autoimmunity, development, proinflammatory, microbes, bacteria, neurology, disorders, epileptic, sfb, host, studies, seizure, type, medicine, mice, nlm, epileptogenesis, immunity, germfree, inflammation, nature, progression, association, commensal, specific, diverse, seizures, factors,
Topics {✒️}
n-methyl-d-aspartate receptor [30] il-17-producing t-helper cells germ-free feeding environment proinflammatory t-cell responses pmc beta search germ-free conditions th17/il-17a signaling anti-inflammatory immune responses pmc copyright notice th17-inducing bacterial species germ-free rodents inflammatory molecules il-1β amygdala-kindled epileptic rats germ-free mice specific antigen-presenting cells interictal interleukin-17a levels t1d-related autoimmune responses competing interests increased il-17a levels immunologically specialized site publisher site pdf british medical journal segmented filamentous bacteria gut-residing bacteria anti-inflammatory cytokines influence infant growth license information pmcid potassium channel antibodies article 42 doi article 155 doi microbial community imbalances experimental autoimmune encephalomyelitis long time recognition gut-residing species splenic il-17-producing inflammatory bowel diseases th17 cell populations human fecal samples th17 cells mediated multicenter twin collaboration poverty-stricken areas aberrant immune response microecosystem-based diagnostics double-edged sword randomized controlled trial middle-income areas [43] pathophysiological lesions observed glutamic acid decarboxylase intestinal th17 cells th17 cell differentiation
Questions {❓}
- Are there any other human commensal microorganisms capable of exerting immunological effects equivalent to those of SFB?
- Autoantibodies in the patient with drug-resistant epilepsy: are we missing a treatable etiology?
- Epilepsy-related psychosis: a role for autoimmunity?
- Epilepsy: an autoimmune disease?
- Getting the bugs out of the immune system: do bacterial microbiota ‘fix’ intestinal T cell responses?
- How can commensal microbes influence the production of IL-17 by Th17 cells?
- Innate immunity: the missing link in neuroprotection and neurodegeneration?
- The immune system and the gut microbiota: friends or foes?
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