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article, cell, google, scholar, laser, cells, surface, cas, pubmed, antimicrobial, graphene, antibacterial, nature, hydrogels, agar, bacteria, size, effects, colony, fig, coli, albicans, agop, hydrogel, surfaces, oxide, bacterial, growth, length, research, pattern, colonies, results, microorganisms, silver, material, aureus, natural, nucleic, effect, model, experimental, figure, cfus, content, journal, resistance, cancer, acids, release,

Topics {✒️}

nature portfolio privacy policy nature advertising national research council social media reprints data protection polymer–graphene oxide composite medical research 36 ros-independent oxidative stress multi-drug resistant microorganisms2 frequency-doubled q-switched lennard-jones truncated form silver-nanoparticles enriched diamond bacteria/fungi solutions graphene-oxide agar hydrogel graphene oxide-based hydrogel personal data high-power laser pulses vitro n-terminal acetylation research research 10 permissions marco de spirito author correspondence original author low-toxicity antimicrobial strategy sterile solutions development figure 1a inset shows nucleic acids release graphene oxide nanowalls ros-independent stress maria chiara braidotti exposure-related health effects show sem images }_{2}}={\ell }_{0} {\mathcal scanning electron microscopy biomimetic antimicrobial cloak privacy intracellular nucleic acids claudio conti nucleic acids leakage coating include antibiotics9 long lasting effects8 n-terminal acetyltransferases effective hydrogel cloak full size image graphene oxide sheets

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• Biocompatibility and antifouling: is there really a link?
• Resistance to antibiotics: are we in the post-antibiotic era?

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         headline:Biomimetic antimicrobial cloak by graphene-oxide agar hydrogel
         description:Antibacterial surfaces have an enormous economic and social impact on the worldwide technological fight against diseases. However, bacteria develop resistance and coatings are often not uniform and not stable in time. The challenge is finding an antibacterial coating that is biocompatible, cost-effective, not toxic, and spreadable over large and irregular surfaces. Here we demonstrate an antibacterial cloak by laser printing of graphene oxide hydrogels mimicking the Cancer Pagurus carapace. We observe up to 90% reduction of bacteria cells. This cloak exploits natural surface patterns evolved to resist to microorganisms infection, and the antimicrobial efficacy of graphene oxide. Cell integrity analysis by scanning electron microscopy and nucleic acids release show bacteriostatic and bactericidal effect. Nucleic acids release demonstrates microorganism cutting, and microscopy reveals cells wrapped by the laser treated gel. A theoretical active matter model confirms our findings. The employment of biomimetic graphene oxide gels opens unique possibilities to decrease infections in biomedical applications and chirurgical equipment; our antibiotic-free approach, based on the geometric reduction of microbial adhesion and the mechanical action of Graphene Oxide sheets, is potentially not affected by bacterial resistance.
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      headline:Biomimetic antimicrobial cloak by graphene-oxide agar hydrogel
      description:Antibacterial surfaces have an enormous economic and social impact on the worldwide technological fight against diseases. However, bacteria develop resistance and coatings are often not uniform and not stable in time. The challenge is finding an antibacterial coating that is biocompatible, cost-effective, not toxic, and spreadable over large and irregular surfaces. Here we demonstrate an antibacterial cloak by laser printing of graphene oxide hydrogels mimicking the Cancer Pagurus carapace. We observe up to 90% reduction of bacteria cells. This cloak exploits natural surface patterns evolved to resist to microorganisms infection, and the antimicrobial efficacy of graphene oxide. Cell integrity analysis by scanning electron microscopy and nucleic acids release show bacteriostatic and bactericidal effect. Nucleic acids release demonstrates microorganism cutting, and microscopy reveals cells wrapped by the laser treated gel. A theoretical active matter model confirms our findings. The employment of biomimetic graphene oxide gels opens unique possibilities to decrease infections in biomedical applications and chirurgical equipment; our antibiotic-free approach, based on the geometric reduction of microbial adhesion and the mechanical action of Graphene Oxide sheets, is potentially not affected by bacterial resistance.
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      name:Department of Physics, University Sapienza, Rome, Italy
      name:Institute for Complex Systems, National Research Council (ISC-CNR), Rome, Italy
      name:Department of Physics, University Sapienza, Rome, Italy

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• mxb-002c5801.gslb.pphosted.com

Name Servers:

• pdns1.ultradns.net
• pdns2.ultradns.net
• pdns3.ultradns.org
• pdns4.ultradns.org
• pdns5.ultradns.info
• pdns6.ultradns.co.uk

CDN Services {📦}

• Crossref