PMC . NCBI . NLM . NIH . GOV {
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We are analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC6232591/.
Title:
The role of 3′ end uridylation in RNA metabolism and cellular physiology - PMC
Description:
Most eukaryotic RNAs are posttranscriptionally modified. The majority of modifications promote RNA maturation, others may regulate function and stability. The 3′ terminal non-templated oligouridylation is a widespread modification affecting many ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
Title:
The role of 3′ end uridylation in RNA metabolism and cellular physiology - PMC
Description:
Most eukaryotic RNAs are posttranscriptionally modified. The majority of modifications promote RNA maturation, others may regulate function and stability. The 3′ terminal non-templated oligouridylation is a widespread modification affecting many ...
Website Age:
27 years and 8 months (reg. 1997-10-02).
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Custom-built
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🌠 Phenomenal Traffic: 5M - 10M visitors per month
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Keywords {🔍}
doi, pubmed, google, scholar, rna, uridylation, article, pmc, free, mrna, cell, mrnas, degradation, mirnas, rnas, disl, decay, terminal, uridylated, role, histone, complex, biol, lin, cleavage, mol, end, translation, expression, cells, processing, activity, science, microrna, decapping, tutase, mirna, exosome, factors, group, small, pathway, human, polya, oligouridylation, regulation, tutases, mammals, hen, stability,
Topics {✒️}
tut6/u6 tutase/tut1/papd2/rbm21 u-insertion/deletion mrna-editing holoenzyme n-terminal cold-shock domain clip-seq-based analyses showed high-throughput cross-linking high-throughput methods designed high-throughput analysis recapitulated high-throughput sequencing analysis nucleic acid-binding domain donut-shaped lsm1-2-3-6-5-7-4 ring pmc beta search ret1-catalyzed uridylylation shapes u-rich rna elements tut4-deficient mice suffer full-length polyadenylated transcripts mirna-directed mrna cleavage target-directed mirna degradation rna-specific ribonucleotidyl transferases hen1 mediated 2′–o-methylation 2′–o-methylation protects srnas unusual rna-binding motif target rna-directed trimming induce replication-dependent decay highly complementary target lsm1p–7p complex 5p2-regulated nuclear poly lsm1–7/pat1 complex binds double-knockout hela cells authors' contributions double-stranded rna viruses highly complementary targets splicing-mediated microrna pathway recruits dcp1–dcp2 complex human b-cells revealed microrna-mediated gene silencing cd4 t-cell activation deadenylation-independent decapping coexists wilms tumor susceptibility publisher site pdf u-rich regions [68] terminal nucleotidyl transferases uridylation-dis3l2-dependent manner drosha-independent manner produce high levels rna-specific activator microrna-directed cleavage u6 snrna terminates wilms tumor predisposition multi-domain utilization anti-dicing nuclease
Questions {❓}
- Are there any cell type-specific or tissue-specific cofactors that modulate TUTase specificity and activity on particular substrates?
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