
PMC . NCBI . NLM . NIH . GOV {
}
Title:
Regulation of neuronal development and function by ROS - PMC
Description:
Reactive oxygen species (ROS) have long been studied as destructive agents in the context of nervous system ageing, disease and degeneration. Their roles as signalling molecules under normal physiological conditions is less well understood. Recent ...
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27 years and 8 months (reg. 1997-10-02).
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Keywords {đ}
pubmed, google, scholar, doi, ros, free, pmc, article, synaptic, neuronal, growth, cell, redox, nadph, actin, neurons, activation, signalling, oxidase, plasticity, protein, neurosci, oxidative, regulation, oxygen, reactive, kinase, activity, biol, system, function, species, hippocampal, superoxide, pathways, oxidation, cone, proteins, cells, dynamics, regulate, nervous, stress, cytoskeletal, factin, sci, polarity, ltp, mical, development,
Topics {âď¸}
calcium/calmodulinâdependent kinase ii transgenic cu/znâsod mice antioxidant/electrophile responsive element spatially localized mpar3/mpar6 nox2âtype nadph oxidase feedâforward mechanism involving growth coneâsubstrate interaction cellâspecific mosaic manipulations oxygenâdependent energy production nadph oxidaseâgenerated ros djâ1âdependent cell transformation rasâpi3kâaktâmtor parvalbuminâexpressing interneurons cerebellar longâterm depression pmc beta search mediates longârange connectivity actinâmediated vesicle tethering neuronal activityâgenerated ros rasâmapk signaling pathways highâthroughput metabolic screening plexinâmediated axonal repulsion block hfsâinduced ltp djâ1β redox sensor activityâregulated structural plasticity ryrâmediated ca2+ release specific aquaporins facilitate hydrogen peroxideâinduced chemotaxis postâtranslational redox modification nerve growth factor disulfideâlinked crmp2 homodimers reactive oxygen species integrinâmediated cell adhesion growth cone interaction growth cone collapse hydrogen peroxideâmediated phosphorylation activityâdependent plasticity growth cone pathfinding jnk/apâ1 signalling pathway nmda receptor activation impaired longâterm memory redoxâsensitive signalling pathways cortical parvalbumin interneurons micalâmediated oxidation decreases nmda receptor stimulation nadph oxidase knockout fastâspiking neurons growth cone engagement rosâregulating neuronal development nadphâdependent monooxygenase symbiotic glialâneuron interactions
Questions {â}
- Gasperini RJ, Pavez M, Thompson AC, Mitchell CB, Hardy H, Young KM, Chilton JK and Foa L (2017) How does calcium interact with the cytoskeleton to regulate growth cone motility during axon pathfinding?
- Sorce S, Stocker R, Seredenina T, Holmdahl R, Aguzzi A, Chio A, Depaulis A, Heitz F, Olofsson P, Olsson T et al (2017) NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: what is the evidence?
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