We are analyzing https://link.springer.com/article/10.1186/s13059-016-0944-x.

Title:
Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity | Genome Biology
Description:
Emerging single-cell epigenomic methods are being developed with the exciting potential to transform our knowledge of gene regulation. Here we review available techniques and future possibilities, arguing that the full potential of single-cell epigenetic studies will be realized through parallel profiling of genomic, transcriptional, and epigenetic information.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Science
Telecommunications

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Link.springer.com could have a money-making trick up its sleeve, but it's undetectable for now.

Keywords {🔍}

singlecell, pubmed, article, cell, google, scholar, cas, cells, dna, sequencing, epigenetic, central, single, methods, chromatin, methylation, bisulfite, nat, stem, analysis, modifications, information, genome, development, parallel, heterogeneity, gene, studies, genomewide, cancer, epigenomic, rnaseq, epigenomics, expression, embryonic, mapping, nucleosome, nature, understanding, regulation, lee, transcriptional, histone, technologies, performed, reveals, approaches, data, full, reik,

Topics {✒️}

single-cell multi-omic technologies full size image employing single-cell multi-omics triple-negative breast cancers high-throughput single-cell labeling single-cell rna-seq data single-molecule real-time sequencing tet-assisted bisulfite sequencing single-cell analysis reveals genome-wide nucleosome occupancy single-cell atac-seq method single-cell multi-omics fluorescence-activated cell sorting single-cell epigenomics techniques cell-type-specific epigenetic marks support genome-wide analysis post-bisulfite adaptor tagging multiplex single-cell profiling single-cell transcriptomics applied single-cell epigenomic approaches single-cell mass cytometry single-cell bisulfite conversion generating single-cell libraries single-tube reaction immediately article download pdf single-cell epigenomics studies post-bisulfite adapter-tagging preparing adapter-tagged libraries combined single-cell technologies single-cell data arise epigenomic cell-state dynamics single-cell bs-seq single-cell methylome landscapes single-cell rna sequencing single-cell rna-seq [38] single-cell rna-seq single-cell transcriptome profiling single-cell sequencing technologies single-molecule sequencing technologies single-cell epigenomic studies provide cutting-edge tools complement single-cell transcriptome rna-seq library preparation single-cell cancer genomics locus-specific bisulfite pcr single-cell sequencing back restrict cell-fate decisions �combinatorial indexing” strategy combinatorial cellular indexing single-cell epigenomic methods

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity
         description:Emerging single-cell epigenomic methods are being developed with the exciting potential to transform our knowledge of gene regulation. Here we review available techniques and future possibilities, arguing that the full potential of single-cell epigenetic studies will be realized through parallel profiling of genomic, transcriptional, and epigenetic information.
         datePublished:2016-04-18T00:00:00Z
         dateModified:2016-04-18T00:00:00Z
         pageStart:1
         pageEnd:10
         license:http://creativecommons.org/publicdomain/zero/1.0/
         sameAs:https://doi.org/10.1186/s13059-016-0944-x
         keywords:
            Epigenetic Mark
            Combinatorial Indexing
            Nucleosome Position
            Nucleosome Occupancy
            Bisulfite Conversion
            Animal Genetics and Genomics
            Human Genetics
            Plant Genetics and Genomics
            Microbial Genetics and Genomics
            Bioinformatics
            Evolutionary Biology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13059-016-0944-x/MediaObjects/13059_2016_944_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13059-016-0944-x/MediaObjects/13059_2016_944_Fig2_HTML.gif
         isPartOf:
            name:Genome Biology
            issn:
               1474-760X
            volumeNumber:17
            type:
               Periodical
               PublicationVolume
         publisher:
            name:BioMed Central
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Stephen J. Clark
               affiliation:
                     name:Babraham Institute
                     address:
                        name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Heather J. Lee
               affiliation:
                     name:Babraham Institute
                     address:
                        name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                        type:PostalAddress
                     type:Organization
                     name:Wellcome Trust Sanger Institute
                     address:
                        name:Wellcome Trust Sanger Institute, Cambridge, UK
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Sébastien A. Smallwood
               affiliation:
                     name:Babraham Institute
                     address:
                        name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                        type:PostalAddress
                     type:Organization
                     name:Friedrich Miescher Institute for Biomedical Research
                     address:
                        name:Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Gavin Kelsey
               affiliation:
                     name:Babraham Institute
                     address:
                        name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                        type:PostalAddress
                     type:Organization
                     name:University of Cambridge
                     address:
                        name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Wolf Reik
               affiliation:
                     name:Babraham Institute
                     address:
                        name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                        type:PostalAddress
                     type:Organization
                     name:Wellcome Trust Sanger Institute
                     address:
                        name:Wellcome Trust Sanger Institute, Cambridge, UK
                        type:PostalAddress
                     type:Organization
                     name:University of Cambridge
                     address:
                        name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
                        type:PostalAddress
                     type:Organization
                     name:University of Cambridge
                     address:
                        name:Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity
      description:Emerging single-cell epigenomic methods are being developed with the exciting potential to transform our knowledge of gene regulation. Here we review available techniques and future possibilities, arguing that the full potential of single-cell epigenetic studies will be realized through parallel profiling of genomic, transcriptional, and epigenetic information.
      datePublished:2016-04-18T00:00:00Z
      dateModified:2016-04-18T00:00:00Z
      pageStart:1
      pageEnd:10
      license:http://creativecommons.org/publicdomain/zero/1.0/
      sameAs:https://doi.org/10.1186/s13059-016-0944-x
      keywords:
         Epigenetic Mark
         Combinatorial Indexing
         Nucleosome Position
         Nucleosome Occupancy
         Bisulfite Conversion
         Animal Genetics and Genomics
         Human Genetics
         Plant Genetics and Genomics
         Microbial Genetics and Genomics
         Bioinformatics
         Evolutionary Biology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13059-016-0944-x/MediaObjects/13059_2016_944_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13059-016-0944-x/MediaObjects/13059_2016_944_Fig2_HTML.gif
      isPartOf:
         name:Genome Biology
         issn:
            1474-760X
         volumeNumber:17
         type:
            Periodical
            PublicationVolume
      publisher:
         name:BioMed Central
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Stephen J. Clark
            affiliation:
                  name:Babraham Institute
                  address:
                     name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Heather J. Lee
            affiliation:
                  name:Babraham Institute
                  address:
                     name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                     type:PostalAddress
                  type:Organization
                  name:Wellcome Trust Sanger Institute
                  address:
                     name:Wellcome Trust Sanger Institute, Cambridge, UK
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Sébastien A. Smallwood
            affiliation:
                  name:Babraham Institute
                  address:
                     name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                     type:PostalAddress
                  type:Organization
                  name:Friedrich Miescher Institute for Biomedical Research
                  address:
                     name:Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Gavin Kelsey
            affiliation:
                  name:Babraham Institute
                  address:
                     name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                     type:PostalAddress
                  type:Organization
                  name:University of Cambridge
                  address:
                     name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Wolf Reik
            affiliation:
                  name:Babraham Institute
                  address:
                     name:Epigenetics Programme, Babraham Institute, Cambridge, UK
                     type:PostalAddress
                  type:Organization
                  name:Wellcome Trust Sanger Institute
                  address:
                     name:Wellcome Trust Sanger Institute, Cambridge, UK
                     type:PostalAddress
                  type:Organization
                  name:University of Cambridge
                  address:
                     name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
                     type:PostalAddress
                  type:Organization
                  name:University of Cambridge
                  address:
                     name:Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Genome Biology
      issn:
         1474-760X
      volumeNumber:17
Organization:
      name:BioMed Central
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Babraham Institute
      address:
         name:Epigenetics Programme, Babraham Institute, Cambridge, UK
         type:PostalAddress
      name:Babraham Institute
      address:
         name:Epigenetics Programme, Babraham Institute, Cambridge, UK
         type:PostalAddress
      name:Wellcome Trust Sanger Institute
      address:
         name:Wellcome Trust Sanger Institute, Cambridge, UK
         type:PostalAddress
      name:Babraham Institute
      address:
         name:Epigenetics Programme, Babraham Institute, Cambridge, UK
         type:PostalAddress
      name:Friedrich Miescher Institute for Biomedical Research
      address:
         name:Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
         type:PostalAddress
      name:Babraham Institute
      address:
         name:Epigenetics Programme, Babraham Institute, Cambridge, UK
         type:PostalAddress
      name:University of Cambridge
      address:
         name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
         type:PostalAddress
      name:Babraham Institute
      address:
         name:Epigenetics Programme, Babraham Institute, Cambridge, UK
         type:PostalAddress
      name:Wellcome Trust Sanger Institute
      address:
         name:Wellcome Trust Sanger Institute, Cambridge, UK
         type:PostalAddress
      name:University of Cambridge
      address:
         name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
         type:PostalAddress
      name:University of Cambridge
      address:
         name:Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Stephen J. Clark
      affiliation:
            name:Babraham Institute
            address:
               name:Epigenetics Programme, Babraham Institute, Cambridge, UK
               type:PostalAddress
            type:Organization
      name:Heather J. Lee
      affiliation:
            name:Babraham Institute
            address:
               name:Epigenetics Programme, Babraham Institute, Cambridge, UK
               type:PostalAddress
            type:Organization
            name:Wellcome Trust Sanger Institute
            address:
               name:Wellcome Trust Sanger Institute, Cambridge, UK
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Sébastien A. Smallwood
      affiliation:
            name:Babraham Institute
            address:
               name:Epigenetics Programme, Babraham Institute, Cambridge, UK
               type:PostalAddress
            type:Organization
            name:Friedrich Miescher Institute for Biomedical Research
            address:
               name:Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
               type:PostalAddress
            type:Organization
      name:Gavin Kelsey
      affiliation:
            name:Babraham Institute
            address:
               name:Epigenetics Programme, Babraham Institute, Cambridge, UK
               type:PostalAddress
            type:Organization
            name:University of Cambridge
            address:
               name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
               type:PostalAddress
            type:Organization
      name:Wolf Reik
      affiliation:
            name:Babraham Institute
            address:
               name:Epigenetics Programme, Babraham Institute, Cambridge, UK
               type:PostalAddress
            type:Organization
            name:Wellcome Trust Sanger Institute
            address:
               name:Wellcome Trust Sanger Institute, Cambridge, UK
               type:PostalAddress
            type:Organization
            name:University of Cambridge
            address:
               name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
               type:PostalAddress
            type:Organization
            name:University of Cambridge
            address:
               name:Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Epigenetics Programme, Babraham Institute, Cambridge, UK
      name:Epigenetics Programme, Babraham Institute, Cambridge, UK
      name:Wellcome Trust Sanger Institute, Cambridge, UK
      name:Epigenetics Programme, Babraham Institute, Cambridge, UK
      name:Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
      name:Epigenetics Programme, Babraham Institute, Cambridge, UK
      name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
      name:Epigenetics Programme, Babraham Institute, Cambridge, UK
      name:Wellcome Trust Sanger Institute, Cambridge, UK
      name:Centre for Trophoblast Research, University of Cambridge, Cambridge, UK
      name:Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK

External Links {🔗}(275)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.05s.

LINK . SPRINGER . COM {}