We are analyzing https://link.springer.com/article/10.1007/s12032-022-01735-7.

Title:
NK and cells with NK-like activities in cancer immunotherapy-clinical perspectives | Medical Oncology
Description:
Natural killer (NK) cells are lymphoid cells of innate immunity that take important roles in immune surveillance. NK cells are considered as a bridge between innate and adaptive immunity, and their infiltration into tumor area is related positively with prolonged patient survival. They are defined as CD16+ CD56+ CD3− cells in clinic. NK cells promote cytolytic effects on target cells and induce their apoptosis. Loss of NK cell cytotoxic activity and reduction in the number of activating receptors are the current issues for application of such cells in cellular immunotherapy, which resulted in the diminished long-term effects. The focus of this review is to discuss about the activity of NK cells and cells with NK-like activity including natural killer T (NKT), cytokine-induced killer (CIK) and lymphokine-activated killer (LAK) cells in immunotherapy of human solid cancers.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Health & Fitness
Education

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We can't see how the site brings in money.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Link.springer.com might be earning cash quietly, but we haven't detected the monetization method.

Keywords {🔍}

pubmed, article, google, scholar, cas, cancer, cells, killer, cell, central, natural, immunotherapy, patients, cytokineinduced, immunol, mortezaee, tumor, study, res, med, phase, clinical, therapy, immune, advanced, oncol, trial, solid, int, clin, tumors, breast, combined, majidpoor, carcinoma, front, sci, treatment, chemotherapy, review, adoptive, mol, effects, activity, cik, anticancer, combination, randomized, immunity, nkt,

Topics {✒️}

granulocyte-macrophage colony-stimulating factor anti-gd2 car-nkt cells month download article/chapter neuroblastoma sk-n-sh cells cxcl12/sdf-1α-secreting glioblastoma cytokine-induced killer cells myeloid-derived suppressor cells retained anti-tumor cd8+ natural-killer-cell surveillance anti-epcam× anti-cd3 nk cell-based therapeutics sars-cov-2 induced disease combined lymphokine-activated killer cytokine-induced killer tim-3-galectin-9 secretory pathway cancer cell therapies anti-tumor activity segregate small-cell lung cancer adenovirus-p53 gene therapy multinational open-label phase �t-cell-ness natural killer cell cancer immunotherapy-clinical perspectives diminished long-term effects cd19-positive lymphoid tumors schmidt-wolf ig invariant nkt cells natural killer cells cell death dis full article pdf lymphokine-activated killer phase ii/iii study high-risk melanoma patients bone marrow transplant tumor-targeted cytokine anti-cancer properties smyth mj dendritic cells loaded th2 cytokine profile antigen-presenting cells breast cancer surgery adoptive cell therapy nk cell responses privacy choices/manage cookies article mortezaee renal cell carcinoma immuno-oncology treatments tumor cell recognition cell responses contribute nk cells engineered

Schema {🗺️}

WebPage:
      mainEntity:
         headline:NK and cells with NK-like activities in cancer immunotherapy-clinical perspectives
         description:Natural killer (NK) cells are lymphoid cells of innate immunity that take important roles in immune surveillance. NK cells are considered as a bridge between innate and adaptive immunity, and their infiltration into tumor area is related positively with prolonged patient survival. They are defined as CD16+ CD56+ CD3− cells in clinic. NK cells promote cytolytic effects on target cells and induce their apoptosis. Loss of NK cell cytotoxic activity and reduction in the number of activating receptors are the current issues for application of such cells in cellular immunotherapy, which resulted in the diminished long-term effects. The focus of this review is to discuss about the activity of NK cells and cells with NK-like activity including natural killer T (NKT), cytokine-induced killer (CIK) and lymphokine-activated killer (LAK) cells in immunotherapy of human solid cancers.
         datePublished:2022-06-18T00:00:00Z
         dateModified:2022-06-18T00:00:00Z
         pageStart:1
         pageEnd:17
         sameAs:https://doi.org/10.1007/s12032-022-01735-7
         keywords:
            Natural killer (NK)
            Dendritic cell (DC)
            Natural killer T (NKT)
            Cytokine-induced killer (CIK)
            Tumor microenvironment (TME)
            Immunotherapy
            Oncology
            Hematology
            Pathology
            Internal Medicine
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig4_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig5_HTML.png
         isPartOf:
            name:Medical Oncology
            issn:
               1559-131X
            volumeNumber:39
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Keywan Mortezaee
               url:http://orcid.org/0000-0003-2004-3465
               affiliation:
                     name:Kurdistan University of Medical Sciences
                     address:
                        name:Department of Anatomy, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Jamal Majidpoor
               affiliation:
                     name:Gonabad University of Medical Sciences
                     address:
                        name:Department of Anatomy, Faculty of Medicine, Infectious Disease Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:NK and cells with NK-like activities in cancer immunotherapy-clinical perspectives
      description:Natural killer (NK) cells are lymphoid cells of innate immunity that take important roles in immune surveillance. NK cells are considered as a bridge between innate and adaptive immunity, and their infiltration into tumor area is related positively with prolonged patient survival. They are defined as CD16+ CD56+ CD3− cells in clinic. NK cells promote cytolytic effects on target cells and induce their apoptosis. Loss of NK cell cytotoxic activity and reduction in the number of activating receptors are the current issues for application of such cells in cellular immunotherapy, which resulted in the diminished long-term effects. The focus of this review is to discuss about the activity of NK cells and cells with NK-like activity including natural killer T (NKT), cytokine-induced killer (CIK) and lymphokine-activated killer (LAK) cells in immunotherapy of human solid cancers.
      datePublished:2022-06-18T00:00:00Z
      dateModified:2022-06-18T00:00:00Z
      pageStart:1
      pageEnd:17
      sameAs:https://doi.org/10.1007/s12032-022-01735-7
      keywords:
         Natural killer (NK)
         Dendritic cell (DC)
         Natural killer T (NKT)
         Cytokine-induced killer (CIK)
         Tumor microenvironment (TME)
         Immunotherapy
         Oncology
         Hematology
         Pathology
         Internal Medicine
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig4_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12032-022-01735-7/MediaObjects/12032_2022_1735_Fig5_HTML.png
      isPartOf:
         name:Medical Oncology
         issn:
            1559-131X
         volumeNumber:39
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Keywan Mortezaee
            url:http://orcid.org/0000-0003-2004-3465
            affiliation:
                  name:Kurdistan University of Medical Sciences
                  address:
                     name:Department of Anatomy, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Jamal Majidpoor
            affiliation:
                  name:Gonabad University of Medical Sciences
                  address:
                     name:Department of Anatomy, Faculty of Medicine, Infectious Disease Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Medical Oncology
      issn:
         1559-131X
      volumeNumber:39
Organization:
      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Kurdistan University of Medical Sciences
      address:
         name:Department of Anatomy, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
         type:PostalAddress
      name:Gonabad University of Medical Sciences
      address:
         name:Department of Anatomy, Faculty of Medicine, Infectious Disease Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Keywan Mortezaee
      url:http://orcid.org/0000-0003-2004-3465
      affiliation:
            name:Kurdistan University of Medical Sciences
            address:
               name:Department of Anatomy, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Jamal Majidpoor
      affiliation:
            name:Gonabad University of Medical Sciences
            address:
               name:Department of Anatomy, Faculty of Medicine, Infectious Disease Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Anatomy, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
      name:Department of Anatomy, Faculty of Medicine, Infectious Disease Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(474)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

5.29s.

LINK . SPRINGER . COM {}