We are analyzing https://link.springer.com/article/10.1007/s10565-019-09496-2.

Title:
Cell death mechanisms in eukaryotes | Cell Biology and Toxicology
Description:
Like the organism they constitute, the cells also die in different ways. The death can be predetermined, programmed, and cleanly executed, as in the case of apoptosis, or it can be traumatic, inflammatory, and sudden as many types of necrosis exemplify. Nevertheless, there are a number of cell deaths—some of them bearing a resemblance to apoptosis and/or necrosis, and many, distinct from each—that serve a multitude of roles in either supporting or disrupting the homoeostasis. Apoptosis is coordinated by death ligands, caspases, b-cell lymphoma-2 (Bcl-2) family proteins, and their downstream effectors. Events that can lead to apoptosis include mitotic catastrophe and anoikis. Necrosis, although it has been considered an abrupt and uncoordinated cell death, has many molecular events associated with it. There are cell death mechanisms that share some standard features with necrosis. These include methuosis, necroptosis, NETosis, pyronecrosis, and pyroptosis. Autophagy, generally a catabolic pathway that operates to ensure cell survival, can also kill the cell through mechanisms such as autosis. Other cell-death mechanisms include entosis, ferroptosis, lysosome-dependent cell death, and parthanatos.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Telecommunications
Education
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We see no obvious way the site makes money.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Link.springer.com has a revenue plan, but it's either invisible or we haven't found it.

Keywords {🔍}

cell, death, pubmed, article, google, scholar, cas, apoptosis, cells, central, cancer, necrosis, mechanisms, sci, biol, autophagy, mol, zhang, necroptosis, ferroptosis, mitochondrial, immunol, human, signaling, differ, entosis, apoptotic, activation, induces, caspase, liu, programmed, molecular, methuosis, pyroptosis, induction, methods, permeability, chem, rep, res, protein, stress, med, wang, inflammatory, pathway, autosis, parthanatos, access,

Topics {✒️}

ros–er–calcium–mitochondria signal pathway reactive oxygen species methuosis-inducing indole-based chalcones grace nirmala & manu lopus month download article/chapter hydrogen peroxide-induced apoptosis valent iron-based nanotherapeutics chalcone-related small molecule lysosome-dependent cell death radiation-induced mitotic catastrophe aβ-induced cell death interleukin-1β-producing monocytes ferrous-supply-regeneration nanoengineering phospho-ripk3 immunohistochemical labeling nonapoptotic cell death necroptosis-dependent signaling pathway granzyme b-mediated apoptosis human tumor cells imaging-guided photodynamic therapy ischemia/reperfusion-induced damage article cell biology cathepsin b-independent necrosis factor 2-dependent mechanism tnf receptor superfamilies full article pdf mitochondrial permeability transition human macrophages infected membrane permeability transition de oliveira si mediated necrosis independently ferroptotic cell death cell death induced necrotic cell death cancer-cell-specific ferroptosis article nirmala ripk3-dependent necroptosis calpain-mediated cleavage endoplasmic reticulum stress programmed cell death mitochondrial calcium overload privacy choices/manage cookies diverse species silmitasertib promotes methuosis lysosomal cell death measuring er stress neutrophil extracellular trap regulated cell death cell death dis cell death mechanisms propofol inhibits parthanatos

Questions {❓}

NETosis: how vital is it?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Cell death mechanisms in eukaryotes
         description:Like the organism they constitute, the cells also die in different ways. The death can be predetermined, programmed, and cleanly executed, as in the case of apoptosis, or it can be traumatic, inflammatory, and sudden as many types of necrosis exemplify. Nevertheless, there are a number of cell deaths—some of them bearing a resemblance to apoptosis and/or necrosis, and many, distinct from each—that serve a multitude of roles in either supporting or disrupting the homoeostasis. Apoptosis is coordinated by death ligands, caspases, b-cell lymphoma-2 (Bcl-2) family proteins, and their downstream effectors. Events that can lead to apoptosis include mitotic catastrophe and anoikis. Necrosis, although it has been considered an abrupt and uncoordinated cell death, has many molecular events associated with it. There are cell death mechanisms that share some standard features with necrosis. These include methuosis, necroptosis, NETosis, pyronecrosis, and pyroptosis. Autophagy, generally a catabolic pathway that operates to ensure cell survival, can also kill the cell through mechanisms such as autosis. Other cell-death mechanisms include entosis, ferroptosis, lysosome-dependent cell death, and parthanatos.
         datePublished:2019-12-09T00:00:00Z
         dateModified:2019-12-09T00:00:00Z
         pageStart:145
         pageEnd:164
         sameAs:https://doi.org/10.1007/s10565-019-09496-2
         keywords:
            Apoptosis
            Autosis
            Entosis
            Ferroptosis
            Methuosis
            Necroptosis
            Necrosis
            NETosis
            Parthanatos
            Pyronecrosis
            Pyroptosis
            Cell Biology
            Pharmacology/Toxicology
            Biochemistry
            general
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig1_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig2_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig3_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig4_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig5_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig6_HTML.png
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig7_HTML.png
         isPartOf:
            name:Cell Biology and Toxicology
            issn:
               1573-6822
               0742-2091
            volumeNumber:36
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Netherlands
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:J. Grace Nirmala
               affiliation:
                     name:University of Mumbai
                     address:
                        name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Manu Lopus
               url:http://orcid.org/0000-0002-4829-3960
               affiliation:
                     name:University of Mumbai
                     address:
                        name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Cell death mechanisms in eukaryotes
      description:Like the organism they constitute, the cells also die in different ways. The death can be predetermined, programmed, and cleanly executed, as in the case of apoptosis, or it can be traumatic, inflammatory, and sudden as many types of necrosis exemplify. Nevertheless, there are a number of cell deaths—some of them bearing a resemblance to apoptosis and/or necrosis, and many, distinct from each—that serve a multitude of roles in either supporting or disrupting the homoeostasis. Apoptosis is coordinated by death ligands, caspases, b-cell lymphoma-2 (Bcl-2) family proteins, and their downstream effectors. Events that can lead to apoptosis include mitotic catastrophe and anoikis. Necrosis, although it has been considered an abrupt and uncoordinated cell death, has many molecular events associated with it. There are cell death mechanisms that share some standard features with necrosis. These include methuosis, necroptosis, NETosis, pyronecrosis, and pyroptosis. Autophagy, generally a catabolic pathway that operates to ensure cell survival, can also kill the cell through mechanisms such as autosis. Other cell-death mechanisms include entosis, ferroptosis, lysosome-dependent cell death, and parthanatos.
      datePublished:2019-12-09T00:00:00Z
      dateModified:2019-12-09T00:00:00Z
      pageStart:145
      pageEnd:164
      sameAs:https://doi.org/10.1007/s10565-019-09496-2
      keywords:
         Apoptosis
         Autosis
         Entosis
         Ferroptosis
         Methuosis
         Necroptosis
         Necrosis
         NETosis
         Parthanatos
         Pyronecrosis
         Pyroptosis
         Cell Biology
         Pharmacology/Toxicology
         Biochemistry
         general
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig1_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig2_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig3_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig4_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig5_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig6_HTML.png
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10565-019-09496-2/MediaObjects/10565_2019_9496_Fig7_HTML.png
      isPartOf:
         name:Cell Biology and Toxicology
         issn:
            1573-6822
            0742-2091
         volumeNumber:36
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Netherlands
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:J. Grace Nirmala
            affiliation:
                  name:University of Mumbai
                  address:
                     name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Manu Lopus
            url:http://orcid.org/0000-0002-4829-3960
            affiliation:
                  name:University of Mumbai
                  address:
                     name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Cell Biology and Toxicology
      issn:
         1573-6822
         0742-2091
      volumeNumber:36
Organization:
      name:Springer Netherlands
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Mumbai
      address:
         name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
         type:PostalAddress
      name:University of Mumbai
      address:
         name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:J. Grace Nirmala
      affiliation:
            name:University of Mumbai
            address:
               name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
               type:PostalAddress
            type:Organization
      name:Manu Lopus
      url:http://orcid.org/0000-0002-4829-3960
      affiliation:
            name:University of Mumbai
            address:
               name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
      name:School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Mumbai, India
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(198)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.06s.

LINK . SPRINGER . COM {}