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Title[redir]:
The cardio-renal-metabolic role of the nod-like receptor protein-3 and senescence-associated secretory phenotype in early sodium/glucose cotransporter-2 inhibitor therapy in people with diabetes who have had a myocardial infarction - PubMed
Description:
Elucidating a role for an SGLT2i in suppressing sterile inflammation will enhance understanding of how they can be used effectively to treat cardiorenal complications and will identify novel pathways for future intervention. Furthermore, the optimal timing of when to initiate SGLT2i therapy post-AMI …
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Keywords {🔍}
diabetes, doi, type, myocardial, infarction, mellitus, acute, pubmed, trial, pmc, empagliflozin, protein, sodiumglucose, inhibitors, patients, pmid, therapy, sglti, study, drug, metabolism, mesh, epub, receptor, cotransporter, ami, tdm, complications, outcomes, macrophages, cardiovascular, effects, review, main, ncbi, similar, articles, references, information, resources, med, nodlike, phenotype, risk, mortality, cardiorenal, protection, nlrp, inflammasome, inflammation,
Topics {✒️}
main page content sodium/glucose cotransporter-2 inhibitors sodium/glucose cotransporter‐2 inhibitors sodium‐glucose cotransporter‐2 inhibitors acute myocardial infarction sodium-glucose transport protein-2 monocyte-derived macrophages myocardial infarction treat cardiorenal complications 33388277 effects cardio-renal-metabolic role macrophages diabetes-related deaths mesh keyword embody trial investigators trial sequential analysis improved cardiorenal outcomes empagliflozin versus placebo 3 months post-ami acute cardiac event united states government decreased inflammatory burden diabetic medicine published esc heart fail cardiac sympathetic activity anti-inflammatory protection pro-inflammatory senescence ischaemic heart disease therapy funding european foundation poor clinical outcomes chronic kidney disease long‐term mortality collaborative meta‐analysis suppressing systemic nod grants health prospective study suppressing sterile inflammation pubmed wordmark pubmed logo secretory phenotype sglt2 inhibitors receptor protein-3 receptor protein 3 embody trial clinical trial diabetes mellitus med sci human services
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