
NATURE . COM {
}
Title:
Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway | Scientific Reports
Description:
Twist is a key transcription factor for Epithelial-mesenchymal transition (EMT), which is a cellular de-differentiation program that promotes invasion and metastasis, confers tumor cells with cancer stem cell (CSC)-like characteristics and increases therapeutic resistance. However, the mechanisms that facilitate the functions of Twist remain unclear. Here we report that Twist overexpression increased expression of PAR1, an upstream regulator of the Hippo pathway; PAR1 promotes invasion, migration and CSC-like properties in breast cancer by activating the transcriptional co-activator TAZ. Our study indicates that Hippo pathway inhibition is required for the increased migratory and invasiveness ability of breast cancer cells in Twist-mediated EMT.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {๐}
- Science
- Education
- Movies
Content Management System {๐}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {๐}
What is the average monthly size of nature.com audience?
๐ Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,554,915 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {๐ธ}
Display Ads {๐ฏ}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {๐ฐ}
Display Ads {๐ฏ}
$536,300 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $357,503 to $983,134.
Keywords {๐}
cells, cancer, cell, twist, breast, par, taz, expression, article, control, emt, hippo, pathway, invasion, google, scholar, cas, snail, vector, data, tumor, fig, experiments, migration, nature, metastasis, signaling, size, analysis, twistmediated, ecadherin, performed, transition, overexpression, activation, ctgf, tdtwist, epithelialmesenchymal, promotes, increased, expressing, presented, wound, assay, sirna, luciferase, wang, growth, epithelial, gene,
Topics {โ๏ธ}
nature portfolio recent research shows privacy policy cancer research nature hela cdna library editing advertising social media 0/ reprints confer csc-related traits speckle-type poz protein pkcepsilon-dependent mechanism snail-mediated e-cadherin repression genome chip-chip analysis twist-expressing t47d cells gsk-3beta-mediated phosphorylation full size image twist-t47d cells compared undergone twist-mediated emt providing ctgf-luc plasmid inflammation-induced cell migration twist-overexpressing t47d cells g-protein-coupled receptors par1/gฮฑ13 binding conformation t47d-twist cell types normal breast epithelia twist-mediated par1 induction mesenchymal marker n-cadherin epithelial marker e-cadherin subsequently activates yap/taz confers tumor cells epithelial-mesenchymal transition epithelialโmesenchymal transition national cancer institute-frederick cellular de-differentiation program matrigel-coated boyden chambers high-gain sensors breast cancer progression stem cell traits human breast cancer permissions real-time pcr luciferase reporter assay mammary epithelial cells twist promotes induction twist-expression affects proliferation cancer stem cell twist-expressing t47d stable cell line
Schema {๐บ๏ธ}
WebPage:
mainEntity:
headline:Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway
description:Twist is a key transcription factor for Epithelial-mesenchymal transition (EMT), which is a cellular de-differentiation program that promotes invasion and metastasis, confers tumor cells with cancer stem cell (CSC)-like characteristics and increases therapeutic resistance. However, the mechanisms that facilitate the functions of Twist remain unclear. Here we report that Twist overexpression increased expression of PAR1, an upstream regulator of the Hippo pathway; PAR1 promotes invasion, migration and CSC-like properties in breast cancer by activating the transcriptional co-activator TAZ. Our study indicates that Hippo pathway inhibition is required for the increased migratory and invasiveness ability of breast cancer cells in Twist-mediated EMT.
datePublished:2016-04-20T00:00:00Z
dateModified:2016-04-20T00:00:00Z
pageStart:1
pageEnd:10
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/srep24606
keywords:
Metastasis
Oncogenes
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig6_HTML.jpg
isPartOf:
name:Scientific Reports
issn:
2045-2322
volumeNumber:6
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Yifan Wang
affiliation:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
type:Organization
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
type:Person
name:Jingyi Liu
affiliation:
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
address:
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
type:PostalAddress
type:Organization
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
type:Organization
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
type:Person
name:Xuhua Ying
affiliation:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
type:Organization
type:Person
name:Pengnian Charles Lin
affiliation:
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
type:Organization
type:Person
name:Binhua P. Zhou
affiliation:
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway
description:Twist is a key transcription factor for Epithelial-mesenchymal transition (EMT), which is a cellular de-differentiation program that promotes invasion and metastasis, confers tumor cells with cancer stem cell (CSC)-like characteristics and increases therapeutic resistance. However, the mechanisms that facilitate the functions of Twist remain unclear. Here we report that Twist overexpression increased expression of PAR1, an upstream regulator of the Hippo pathway; PAR1 promotes invasion, migration and CSC-like properties in breast cancer by activating the transcriptional co-activator TAZ. Our study indicates that Hippo pathway inhibition is required for the increased migratory and invasiveness ability of breast cancer cells in Twist-mediated EMT.
datePublished:2016-04-20T00:00:00Z
dateModified:2016-04-20T00:00:00Z
pageStart:1
pageEnd:10
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/srep24606
keywords:
Metastasis
Oncogenes
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep24606/MediaObjects/41598_2016_Article_BFsrep24606_Fig6_HTML.jpg
isPartOf:
name:Scientific Reports
issn:
2045-2322
volumeNumber:6
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Yifan Wang
affiliation:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
type:Organization
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
type:Person
name:Jingyi Liu
affiliation:
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
address:
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
type:PostalAddress
type:Organization
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
type:Organization
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
type:Person
name:Xuhua Ying
affiliation:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
type:Organization
type:Person
name:Pengnian Charles Lin
affiliation:
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
type:Organization
type:Person
name:Binhua P. Zhou
affiliation:
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Scientific Reports
issn:
2045-2322
volumeNumber:6
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
address:
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
type:PostalAddress
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Yifan Wang
affiliation:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
type:Organization
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
name:Jingyi Liu
affiliation:
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
address:
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
type:PostalAddress
type:Organization
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
type:Organization
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
name:Xuhua Ying
affiliation:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine
address:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
type:PostalAddress
type:Organization
name:Pengnian Charles Lin
affiliation:
name:Center for Cancer Research, National Cancer Institute-Frederick
address:
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
type:PostalAddress
type:Organization
name:Binhua P. Zhou
affiliation:
name:Markey Cancer Center, the University of Kentucky, College of Medicine
address:
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
type:PostalAddress
type:Organization
PostalAddress:
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
name:The State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
name:Cancer Institute of Integrative Medicine, Zhejiang Academy of Chinese Medicine, Hangzhou, China
name:Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA
name:Department of Molecular and Cellular Biochemistry, Markey Cancer Center, the University of Kentucky, College of Medicine, Lexington, United States of America
External Links {๐}(84)
- Financial intake of https://doi.org/10.1038%2Fnrc1370
- Income figures for http://scholar.google.com/scholar_lookup?&title=Dissecting%20the%20metastatic%20cascade&journal=Nat%20Rev%20Cancer.&doi=10.1038%2Fnrc1370&volume=4&pages=448-456&publication_year=2004&author=Pantel%2CK&author=Brakenhoff%2CRH
- How much profit does https://doi.org/10.1038%2Fnrc2620 make?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Transitions%20between%20epithelial%20and%20mesenchymal%20states%3A%20acquisition%20of%20malignant%20and%20stem%20cell%20traits&journal=Nat%20Rev%20Cancer.&doi=10.1038%2Fnrc2620&volume=9&pages=265-273&publication_year=2009&author=Polyak%2CK&author=Weinberg%2CRA generate?
- What's the income generated by https://doi.org/10.1016%2Fj.cell.2009.11.007 each month?
- What's http://scholar.google.com/scholar_lookup?&title=Epithelial-mesenchymal%20transitions%20in%20development%20and%20disease&journal=Cell.&doi=10.1016%2Fj.cell.2009.11.007&volume=139&pages=871-890&publication_year=2009&author=Thiery%2CJP&author=Acloque%2CH&author=Huang%2CRY&author=Nieto%2CMA's gross income?
- How much does https://doi.org/10.1158%2F0008-5472.CAN-07-2017 gross monthly?
- What's the income of http://scholar.google.com/scholar_lookup?&title=Epithelial-mesenchymal%20transition%20in%20breast%20cancer%20relates%20to%20the%20basal-like%20phenotype&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-07-2017&volume=68&pages=989-997&publication_year=2008&author=Sarrio%2CD?
- What are the earnings of https://doi.org/10.1172%2FJCI39104?
- http://scholar.google.com/scholar_lookup?&title=The%20basics%20of%20epithelial-mesenchymal%20transition&journal=J%20Clin%20Invest.&doi=10.1172%2FJCI39104&volume=119&pages=1420-1428&publication_year=2009&author=Kalluri%2CR&author=Weinberg%2CRA income
- How much cash flow does https://doi.org/10.1016%2Fj.cell.2004.06.006 have monthly?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Twist%2C%20a%20master%20regulator%20of%20morphogenesis%2C%20plays%20an%20essential%20role%20in%20tumor%20metastasis&journal=Cell.&doi=10.1016%2Fj.cell.2004.06.006&volume=117&pages=927-939&publication_year=2004&author=Yang%2CJ
- How much does https://doi.org/10.1101%2Fgad.5.9.1568 earn?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=twist%20and%20snail%20as%20positive%20and%20negative%20regulators%20during%20Drosophila%20mesoderm%20development&journal=Genes%20Dev.&doi=10.1101%2Fgad.5.9.1568&volume=5&pages=1568-1576&publication_year=1991&author=Leptin%2CM?
- What's the income of https://doi.org/10.1101%2Fgad.1509607?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Whole-genome%20ChIP-chip%20analysis%20of%20Dorsal%2C%20Twist%20and%20Snail%20suggests%20integration%20of%20diverse%20patterning%20processes%20in%20the%20Drosophila%20embryo&journal=Genes%20Dev.&doi=10.1101%2Fgad.1509607&volume=21&pages=385-390&publication_year=2007&author=Zeitlinger%2CJ?
- How much income does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15280447 have?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Protease-activated%20receptors%20%28PAR1%20and%20PAR2%29%20contribute%20to%20tumor%20cell%20motility%20and%20metastasis&journal=Mol%20Cancer%20Res.&volume=2&pages=395-402&publication_year=2004&author=Shi%2CX&author=Gangadharan%2CB&author=Brass%2CLF&author=Ruf%2CW&author=Mueller%2CBM produce monthly?
- What is the monthly revenue of https://doi.org/10.1016%2Fj.cell.2004.12.018?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=PAR1%20is%20a%20matrix%20metalloprotease-1%20receptor%20that%20promotes%20invasion%20and%20tumorigenesis%20of%20breast%20cancer%20cells&journal=Cell.&doi=10.1016%2Fj.cell.2004.12.018&volume=120&pages=303-313&publication_year=2005&author=Boire%2CA
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=1596884
- What's the income of http://scholar.google.com/scholar_lookup?&title=Effect%20of%20thrombin%20treatment%20of%20tumor%20cells%20on%20adhesion%20of%20tumor%20cells%20to%20platelets%20in%20vitro%20and%20tumor%20metastasis%20in%20vivo&journal=Cancer%20Res.&volume=52&pages=3267-3272&publication_year=1992&author=Nierodzik%2CML&author=Kajumo%2CF&author=Karpatkin%2CS?
- How much does https://doi.org/10.3727%2F0965040042380496 pull in monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=PAR1-type%20thrombin%20receptor%20stimulates%20migration%20and%20matrix%20adhesion%20of%20human%20colon%20carcinoma%20cells%20by%20a%20PKCepsilon-dependent%20mechanism&journal=Oncol%20Res.&doi=10.3727%2F0965040042380496&volume=14&pages=475-482&publication_year=2004&author=Heider%2CI net monthly?
- Get to know what's the income of https://doi.org/10.1038%2Fnm0898-909
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Thrombin%20receptor%20overexpression%20in%20malignant%20and%20physiological%20invasion%20processes&journal=Nat%20Med&doi=10.1038%2Fnm0898-909&volume=4&pages=909-914&publication_year=1998&author=Even-Ram%2CS bring in?
- How much does https://doi.org/10.1101%2Fgad.197582.112 bring in each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20the%20Hippo-YAP%20pathway%20by%20protease-activated%20receptors%20%28PARs%29&journal=Genes%20Dev.&doi=10.1101%2Fgad.197582.112&volume=26&pages=2138-2143&publication_year=2012&author=Mo%2CJS&author=Yu%2CFX&author=Gong%2CR&author=Brown%2CJH&author=Guan%2CKL rake in every month?
- How much income does https://doi.org/10.1016%2Fj.devcel.2010.09.011 have?
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=The%20hippo%20signaling%20pathway%20in%20development%20and%20cancer&journal=Dev%20Cell.&doi=10.1016%2Fj.devcel.2010.09.011&volume=19&pages=491-505&publication_year=2010&author=Pan%2CD?
- Financial intake of https://doi.org/10.1158%2F0008-5472.CAN-09-0187
- http://scholar.google.com/scholar_lookup?&title=Blockade%20of%20PAR1%20signaling%20with%20cell-penetrating%20pepducins%20inhibits%20Akt%20survival%20pathways%20in%20breast%20cancer%20cells%20and%20suppresses%20tumor%20survival%20and%20metastasis&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-09-0187&volume=69&pages=6223-6231&publication_year=2009&author=Yang%2CE's revenue stream
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11479236?
- Get to know http://scholar.google.com/scholar_lookup?&title=Signaling%20from%20protease-activated%20receptor-1%20inhibits%20migration%20and%20invasion%20of%20breast%20cancer%20cells&journal=Cancer%20Res.&volume=61&pages=5933-5940&publication_year=2001&author=Kamath%2CL&author=Meydani%2CA&author=Foss%2CF&author=Kuliopulos%2CA's earnings
- Monthly income for https://doi.org/10.1101%2Fgad.1909210
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=The%20Hippo-YAP%20pathway%20in%20organ%20size%20control%20and%20tumorigenesis%3A%20an%20updated%20version&journal=Genes%20Dev.&doi=10.1101%2Fgad.1909210&volume=24&pages=862-874&publication_year=2010&author=Zhao%2CB&author=Li%2CL&author=Lei%2CQ&author=Guan%2CKL is on a monthly basis
- How much does https://doi.org/10.1073%2Fpnas.0700763104 bring in each month?
- How much income is http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2007PNAS..104.5662M earning monthly?
- How much income is http://scholar.google.com/scholar_lookup?&title=Protease-activated%20receptor-3%20%28PAR3%29%20regulates%20PAR1%20signaling%20by%20receptor%20dimerization&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.0700763104&volume=104&pages=5662-5667&publication_year=2007&author=McLaughlin%2CJN&author=Patterson%2CMM&author=Malik%2CAB earning monthly?
- https://doi.org/10.1016%2Fj.cell.2011.09.048's total income per month
- How much does http://scholar.google.com/scholar_lookup?&title=The%20Hippo%20transducer%20TAZ%20confers%20cancer%20stem%20cell-related%20traits%20on%20breast%20cancer%20cells&journal=Cell.&doi=10.1016%2Fj.cell.2011.09.048&volume=147&pages=759-772&publication_year=2011&author=Cordenonsi%2CM net monthly?
- How much does https://doi.org/10.1128%2FMCB.01874-07 earn?
- Income figures for http://scholar.google.com/scholar_lookup?&title=TAZ%20promotes%20cell%20proliferation%20and%20epithelial-mesenchymal%20transition%20and%20is%20inhibited%20by%20the%20hippo%20pathway&journal=Mol%20Cell%20Biol.&doi=10.1128%2FMCB.01874-07&volume=28&pages=2426-2436&publication_year=2008&author=Lei%2CQY
- What's the income generated by https://doi.org/10.1101%2Fgad.1664408 each month?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=TEAD%20mediates%20YAP-dependent%20gene%20induction%20and%20growth%20control&journal=Genes%20Dev.&doi=10.1101%2Fgad.1664408&volume=22&pages=1962-1971&publication_year=2008&author=Zhao%2CB is on a monthly basis
- What's the financial outcome of https://doi.org/10.1101%2Fgad.1843810?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=A%20coordinated%20phosphorylation%20by%20Lats%20and%20CK1%20regulates%20YAP%20stability%20through%20SCF%28beta-TRCP%29&journal=Genes%20Dev.&doi=10.1101%2Fgad.1843810&volume=24&pages=72-85&publication_year=2010&author=Zhao%2CB&author=Li%2CL&author=Tumaneng%2CK&author=Wang%2CCY&author=Guan%2CKL?
- How much revenue does https://doi.org/10.1158%2F0008-5472.CAN-10-2711 generate?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Taxol%20resistance%20in%20breast%20cancer%20cells%20is%20mediated%20by%20the%20hippo%20pathway%20component%20TAZ%20and%20its%20downstream%20transcriptional%20targets%20Cyr61%20and%20CTGF&journal=Cancer%20Res.&doi=10.1158%2F0008-5472.CAN-10-2711&volume=71&pages=2728-2738&publication_year=2011&author=Lai%2CD&author=Ho%2CKC&author=Hao%2CY&author=Yang%2CX
- See how much https://doi.org/10.1016%2Fj.ccr.2009.03.016 makes per month
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Stabilization%20of%20snail%20by%20NF-kappaB%20is%20required%20for%20inflammation-induced%20cell%20migration%20and%20invasion&journal=Cancer%20Cell.&doi=10.1016%2Fj.ccr.2009.03.016&volume=15&pages=416-428&publication_year=2009&author=Wu%2CY generate?
- How much does https://doi.org/10.1038%2Fncb1173 gross monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Dual%20regulation%20of%20Snail%20by%20GSK-3beta-mediated%20phosphorylation%20in%20control%20of%20epithelial-mesenchymal%20transition&journal=Nat%20Cell%20Biol.&doi=10.1038%2Fncb1173&volume=6&pages=931-940&publication_year=2004&author=Zhou%2CBP gross monthly?
- What's the revenue for https://doi.org/10.1172%2FJCI57349?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=G9a%20interacts%20with%20Snail%20and%20is%20critical%20for%20Snail-mediated%20E-cadherin%20repression%20in%20human%20breast%20cancer&journal=J%20Clin%20Invest.&doi=10.1172%2FJCI57349&volume=122&pages=1469-1486&publication_year=2012&author=Dong%2CC is on a monthly basis
- How much money does https://link.springer.com/doi/10.1186/bcr2106 make?
- http://scholar.google.com/scholar_lookup?&title=Mammosphere%20culture%20of%20metastatic%20breast%20cancer%20cells%20enriches%20for%20tumorigenic%20breast%20cancer%20cells&journal=Breast%20Cancer%20Res.&doi=10.1186%2Fbcr2106&volume=10&publication_year=2008&author=Grimshaw%2CMJ's total income per month
- What's the profit of https://doi.org/10.1371%2Fjournal.pone.0064388?
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2013PLoSO...864388S pull in monthly?
- What's http://scholar.google.com/scholar_lookup?&title=In%20vitro%20analysis%20of%20breast%20cancer%20cell%20line%20tumourspheres%20and%20primary%20human%20breast%20epithelia%20mammospheres%20demonstrates%20inter-%20and%20intrasphere%20heterogeneity&journal=PLoS%20One.&doi=10.1371%2Fjournal.pone.0064388&volume=8&publication_year=2013&author=Smart%2CCE's gross income?
- Financial intake of https://citation-needed.springer.com/v2/references/10.1038/srep24606?format=refman&flavour=references
- How profitable is https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yifan%20Wang?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yifan%20Wang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en gross monthly?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jingyi%20Liu income
- How much money does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jingyi%20Liu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- What's the monthly income of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Xuhua%20Ying?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Xuhua%20Ying%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in?
- What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Pengnian%20Charles%20Lin?
- What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Pengnian%20Charles%20Lin%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Binhua%20P.%20Zhou produce monthly?
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Binhua%20P.%20Zhou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's revenue stream
- How much money does http://creativecommons.org/licenses/by/4.0/ generate?
- Check the income stats for https://s100.copyright.com/AppDispatchServlet?title=Twist-mediated%20Epithelial-mesenchymal%20Transition%20Promotes%20Breast%20Tumor%20Cell%20Invasion%20via%20Inhibition%20of%20Hippo%20Pathway&author=Yifan%20Wang%20et%20al&contentID=10.1038%2Fsrep24606©right=The%20Author%28s%29&publication=2045-2322&publicationDate=2016-04-20&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY
- How much cash flow does https://crossmark.crossref.org/dialog/?doi=10.1038/srep24606 have monthly?
- How much revenue does https://citation-needed.springer.com/v2/references/10.1038/srep24606?format=refman&flavour=citation generate?
- What's https://doi.org/10.1007/s11033-023-09167-w's gross income?
- See how much https://doi.org/10.1038/s41419-023-05568-8 makes per month
- Learn how profitable https://doi.org/10.1007/s11033-022-07590-z is on a monthly basis
- Get to know https://doi.org/10.1007/s12094-022-02851-6's earnings
- What's the revenue for https://doi.org/10.1186/s12935-021-01999-5?
- Get to know https://www.protocols.io/'s earnings
- Income figures for https://www.natureindex.com/
- How much profit does http://www.naturechina.com make?
- What's the financial gain of https://www.natureasia.com/ja-jp?
Analytics and Tracking {๐}
- Google Tag Manager
Libraries {๐}
- Prism.js
- Zoom.js
Emails and Hosting {โ๏ธ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {๐ฆ}
- Crossref