
NATURE . COM {
}
Title:
Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo | Scientific Reports
Description:
Reactivation of wild-type p53 (wt-p53) function is an attractive therapeutic approach to p53-defective cancers. An ideal p53-based gene therapy should restore wt-p53 production and reduces mutant p53 transcripts simultaneously. In this study, we described an alternative strategy named as trans-splicing that repaired mutant p53 transcripts in hepatocellular carcinoma (HCC) cells. The plasmids which encoded a pre-trans-splicing molecule (PTM) targeting intron 6 of p53 were constructed and then transfected into HCC cells carrying p53 mutation. Phenotypic changes of HCC cells induced by p53-PTM were analyzed through cell cycle, cell apoptosis and the expression of p53 downstream target genes. Spliceosome mediated RNA trans-splicing (SMaRT) reduced mutant p53 transcripts and produced functional wt-p53 protein after the delivery of p53-PTM plasmids, which resulted in phenotype correction of HCC cells. In tumor xenografts established by p53-mutated HCC cells, adenovirus encoding p53-PTM induced cell cycle arrest and apoptosis and then blocked the growth of tumors in mice. Collectively, our results demonstrated for the first time that mutant p53 transcripts were functionally corrected in p53-defective HCC cells and xenografts using trans-splicing, which indicated the feasibility of using trans-splicing to repair p53 mutation in p53-defective cancers.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Science
- Education
- Telecommunications
Content Management System {π}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of nature.com audience?
π Monumental Traffic: 20M - 50M visitors per month
Based on our best estimate, this website will receive around 42,555,829 visitors per month in the current month.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {πΈ}
Display Ads {π―}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
Display Ads {π―}
$536,300 per month
Estimations show Nature.com's display ad online revenue falls between $357,511 and $983,155 per month.
Keywords {π}
cells, mutant, article, pubmed, cancer, google, scholar, cell, hcc, cas, transcripts, plcprf, pptm, transsplicing, expression, tumor, figure, wtp, repair, tumors, growth, apoptosis, genes, transfected, nature, gene, mutation, cycle, smart, human, rna, mice, adenovirus, hepatocellular, carcinoma, demonstrated, genetic, xenograft, pdefective, study, mutations, liver, rtpcr, central, function, protein, correction, supplementary, vitro, therapy,
Topics {βοΈ}
nature portfolio privacy policy providing pcmv-neo-bam wtp53 plasmid pcmv-neo-bam wtp53 hyper-igm x-linked immunodeficiency advertising diverse nature spliceosome-mediated rna trans-splicing nature reviews evaluate trans-splicing-mediated repair p53 pre-trans-splicing molecules nature 415 nature p53-ptm-e7-11 trans-activated social media trans-splicing ribozymes-mediate repair ad-p53ptm-e7-11 group manifested pre-established plc/prf/5 xenografts trans-spliced p53 rnas 0/ reprints adenovirus encoding p53-ptm p53 research p53-based cancer therapies trans-spliced p53 rna vectors expressing p53-ptm italy trans splicing-mediated revision pre-trans-splicing molecule providing pcyclinb-prom-luc pre-mrna trans-splicing wild-type p53 activity trans-splicing-mediated repair plasmid carrying p53-ptm wild-type human p53 trans-activate downstream genes sybr green qrt-pcr p53-dependent downstream genes restores wt-p53 activity defective target pre-mrna restored wt-p53 activities mature wt-p53 transcripts activating cyclin-dependent kinase blocking mdm2-induced degradation yeast branch-point consensus wild-type p53 function restore wt-p53 production p53-dependent target genes plc/prf/5 cells led induces wt-p53 production research
Questions {β}
- Splicing out the West?
- P53 Isoforms: An Intracellular Microprocessor?
- P53-based cancer therapies: Is defective p53 the Achilles heel of the tumor?
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo
description:Reactivation of wild-type p53 (wt-p53) function is an attractive therapeutic approach to p53-defective cancers. An ideal p53-based gene therapy should restore wt-p53 production and reduces mutant p53 transcripts simultaneously. In this study, we described an alternative strategy named as trans-splicing that repaired mutant p53 transcripts in hepatocellular carcinoma (HCC) cells. The plasmids which encoded a pre-trans-splicing molecule (PTM) targeting intron 6 of p53 were constructed and then transfected into HCC cells carrying p53 mutation. Phenotypic changes of HCC cells induced by p53-PTM were analyzed through cell cycle, cell apoptosis and the expression of p53 downstream target genes. Spliceosome mediated RNA trans-splicing (SMaRT) reduced mutant p53 transcripts and produced functional wt-p53 protein after the delivery of p53-PTM plasmids, which resulted in phenotype correction of HCC cells. In tumor xenografts established by p53-mutated HCC cells, adenovirus encoding p53-PTM induced cell cycle arrest and apoptosis and then blocked the growth of tumors in mice. Collectively, our results demonstrated for the first time that mutant p53 transcripts were functionally corrected in p53-defective HCC cells and xenografts using trans-splicing, which indicated the feasibility of using trans-splicing to repair p53 mutation in p53-defective cancers.
datePublished:2015-03-03T00:00:00Z
dateModified:2015-03-03T00:00:00Z
pageStart:1
pageEnd:8
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/srep08705
keywords:
Targeted therapies
Translational research
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig4_HTML.jpg
isPartOf:
name:Scientific Reports
issn:
2045-2322
volumeNumber:5
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Xingxing He
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Fang Liu
affiliation:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Jingjun Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yunan Zhang
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Junwei Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Haitao Shang
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qian Dou
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qiu Zhao
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yuhu Song
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo
description:Reactivation of wild-type p53 (wt-p53) function is an attractive therapeutic approach to p53-defective cancers. An ideal p53-based gene therapy should restore wt-p53 production and reduces mutant p53 transcripts simultaneously. In this study, we described an alternative strategy named as trans-splicing that repaired mutant p53 transcripts in hepatocellular carcinoma (HCC) cells. The plasmids which encoded a pre-trans-splicing molecule (PTM) targeting intron 6 of p53 were constructed and then transfected into HCC cells carrying p53 mutation. Phenotypic changes of HCC cells induced by p53-PTM were analyzed through cell cycle, cell apoptosis and the expression of p53 downstream target genes. Spliceosome mediated RNA trans-splicing (SMaRT) reduced mutant p53 transcripts and produced functional wt-p53 protein after the delivery of p53-PTM plasmids, which resulted in phenotype correction of HCC cells. In tumor xenografts established by p53-mutated HCC cells, adenovirus encoding p53-PTM induced cell cycle arrest and apoptosis and then blocked the growth of tumors in mice. Collectively, our results demonstrated for the first time that mutant p53 transcripts were functionally corrected in p53-defective HCC cells and xenografts using trans-splicing, which indicated the feasibility of using trans-splicing to repair p53 mutation in p53-defective cancers.
datePublished:2015-03-03T00:00:00Z
dateModified:2015-03-03T00:00:00Z
pageStart:1
pageEnd:8
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/srep08705
keywords:
Targeted therapies
Translational research
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig4_HTML.jpg
isPartOf:
name:Scientific Reports
issn:
2045-2322
volumeNumber:5
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Xingxing He
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Fang Liu
affiliation:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Jingjun Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yunan Zhang
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Junwei Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Haitao Shang
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qian Dou
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qiu Zhao
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yuhu Song
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Scientific Reports
issn:
2045-2322
volumeNumber:5
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Xingxing He
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Fang Liu
affiliation:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Jingjun Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Yunan Zhang
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Junwei Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Haitao Shang
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Qian Dou
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Qiu Zhao
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Yuhu Song
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
PostalAddress:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
External Links {π}(192)
- What's the income of http://publications.cancerresearchuk.org/downloads/Product/CS_INFOG_WORLD_MORT.PDF?
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Global%20cancer%20statistics&journal=CA%3A%20a%20cancer%20journal%20for%20clinicians&volume=61&pages=69-90&publication_year=2011&author=Jemal%2CA?
- Financial intake of https://doi.org/10.1002%2Fhep.20933
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16250051?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Management%20of%20hepatocellular%20carcinoma&journal=Hepatology&doi=10.1002%2Fhep.20933&volume=42&pages=1208-1236&publication_year=2005&author=Bruix%2CJ&author=Sherman%2CM is on a monthly basis
- Get to know what's the income of https://doi.org/10.1016%2Fj.jhep.2009.11.015
- What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20022654?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Risk%20of%20HCC%3A%20genetic%20heterogeneity%20and%20complex%20genetics&journal=Journal%20of%20hepatology&doi=10.1016%2Fj.jhep.2009.11.015&volume=52&pages=252-257&publication_year=2010&author=Dragani%2CTA?
- https://doi.org/10.1016%2FS0168-8278%2812%2960009-9's total income per month
- Check the income stats for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22300468
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Management%20of%20HCC&journal=Journal%20of%20hepatology&doi=10.1016%2FS0168-8278%2812%2960009-9&volume=56&pages=S75-87&publication_year=2012&author=de%20Lope%2CCR&author=Tremosini%2CS&author=Forner%2CA&author=Reig%2CM&author=Bruix%2CJ?
- What's the financial outcome of https://doi.org/10.3748%2Fwjg.14.1720?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18350603?
- Explore the financials of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695912
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Tumor%20suppressor%20and%20hepatocellular%20carcinoma&journal=World%20J%20Gastroenterol&doi=10.3748%2Fwjg.14.1720&volume=14&pages=1720-1733&publication_year=2008&author=Martin%2CJ&author=Dufour%2CJF
- What's the monthly money flow for https://doi.org/10.1101%2Fcshperspect.a001115?
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20452944 make?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845198
- How much profit does http://scholar.google.com/scholar_lookup?&title=Mouse%20models%20of%20p53%20functions&journal=Cold%20Spring%20Harb%20Perspect%20Biol&doi=10.1101%2Fcshperspect.a001115&volume=2&publication_year=2010&author=Lozano%2CG make?
- What's the profit of https://doi.org/10.1056%2FNEJMp0707422?
- What is the monthly revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18094374?
- How profitable is http://scholar.google.com/scholar_lookup?&title=p53-master%20and%20commander&journal=N%20Engl%20J%20Med&doi=10.1056%2FNEJMp0707422&volume=357&pages=2539-2541&publication_year=2007&author=Foulkes%2CWD?
- What's the monthly income of https://doi.org/10.1016%2Fj.cell.2009.04.050?
- Find out how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19450511 earns monthly
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737742 bring in each month?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Modes%20of%20p53%20regulation&journal=Cell&doi=10.1016%2Fj.cell.2009.04.050&volume=137&pages=609-622&publication_year=2009&author=Kruse%2CJP&author=Gu%2CW bring in?
- What's the revenue for https://doi.org/10.1038%2Fncb2641?
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23263379
- Find out how much http://scholar.google.com/scholar_lookup?&title=p53%20mutations%20in%20cancer&journal=Nature%20cell%20biology&doi=10.1038%2Fncb2641&volume=15&pages=2-8&publication_year=2013&author=Muller%2CPA&author=Vousden%2CKH earns monthly
- What's the income of https://doi.org/10.1002%2Fpath.2784?
- What is the monthly revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21125670?
- http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20mutant%20p53%20in%20human%20cancer&journal=The%20Journal%20of%20pathology&doi=10.1002%2Fpath.2784&volume=223&pages=116-126&publication_year=2011&author=Goh%2CAM&author=Coffill%2CCR&author=Lane%2CDP's revenue stream
- Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14633666
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Mouse%20models%20to%20study%20the%20interaction%20of%20risk%20factors%20for%20human%20liver%20cancer&journal=Cancer%20Res&volume=63&pages=7553-7562&publication_year=2003&author=Sell%2CS
- How much does https://doi.org/10.1002%2Fhep.22580 generate monthly?
- What's the financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19003900?
- Get to know http://scholar.google.com/scholar_lookup?&title=Molecular%20mechanisms%20of%20hepatocellular%20carcinoma&journal=Hepatology&doi=10.1002%2Fhep.22580&volume=48&pages=2047-2063&publication_year=2008&author=Aravalli%2CRN&author=Steer%2CCJ&author=Cressman%2CEN's earnings
- See how much https://doi.org/10.1016%2Fj.ejca.2012.03.001 makes per month
- Find out how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22459764 earns monthly
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395767's financial summary
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Alterations%20of%20TP53%20are%20associated%20with%20a%20poor%20outcome%20for%20patients%20with%20hepatocellular%20carcinoma%3A%20evidence%20from%20a%20systematic%20review%20and%20meta-analysis&journal=Eur%20J%20Cancer&doi=10.1016%2Fj.ejca.2012.03.001&volume=48&pages=2328-2338&publication_year=2012&author=Liu%2CJ
- https://doi.org/10.1038%2Fsj.onc.1210291's financial summary
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17401432's revenue stream
- What's http://scholar.google.com/scholar_lookup?&title=Structure-function-rescue%3A%20the%20diverse%20nature%20of%20common%20p53%20cancer%20mutants&journal=Oncogene&doi=10.1038%2Fsj.onc.1210291&volume=26&pages=2226-2242&publication_year=2007&author=Joerger%2CAC&author=Fersht%2CAR's gross income?
- Discover the revenue of https://doi.org/10.1101%2Fgad.190678.112
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Mutant%20p53%3A%20one%20name%2C%20many%20proteins&journal=Genes%20%26%20development&doi=10.1101%2Fgad.190678.112&volume=26&pages=1268-1286&publication_year=2012&author=Freed-Pastor%2CWA&author=Prives%2CC generate?
- What's the monthly money flow for https://doi.org/10.1002%2Fhed.20529?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17230559?
- How much money does http://scholar.google.com/scholar_lookup?&title=Restoration%20of%20wild-type%20p53%20function%20in%20human%20cancer%3A%20relevance%20for%20tumor%20therapy&journal=Head%20Neck&doi=10.1002%2Fhed.20529&volume=29&pages=272-284&publication_year=2007&author=Bossi%2CG&author=Sacchi%2CA generate?
- What's the financial gain of https://doi.org/10.1038%2Fsj.onc.1210295?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17401433 earn?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Reactivation%20of%20mutant%20p53%3A%20molecular%20mechanisms%20and%20therapeutic%20potential&journal=Oncogene&doi=10.1038%2Fsj.onc.1210295&volume=26&pages=2243-2254&publication_year=2007&author=Selivanova%2CG&author=Wiman%2CKG bring in?
- What's the financial outcome of https://doi.org/10.1038%2Fnrclinonc.2010.174?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20975744 gross monthly?
- How much profit is http://scholar.google.com/scholar_lookup?&title=Translating%20p53%20into%20the%20clinic&journal=Nature%20reviews.%20Clinical%20oncology&doi=10.1038%2Fnrclinonc.2010.174&volume=8&pages=25-37&publication_year=2011&author=Cheok%2CCF&author=Verma%2CCS&author=Baselga%2CJ&author=Lane%2CDP making per month?
- What's the total monthly financial gain of https://doi.org/10.1093%2Fcarcin%2Fbgl214?
- Learn about the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17088261
- What's http://scholar.google.com/scholar_lookup?&title=p53-based%20cancer%20therapies%3A%20Is%20defective%20p53%20the%20Achilles%20heel%20of%20the%20tumor&journal=Carcinogenesis&doi=10.1093%2Fcarcin%2Fbgl214&volume=28&pages=13-20&publication_year=2007&author=Levesque%2CAA&author=Eastman%2CA's gross income?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21765642 bring in?
- What are the earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134396?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Recent%20advances%20in%20p53%20research%20and%20cancer%20treatment&journal=J%20Biomed%20Biotechnol&volume=2011&publication_year=2011&author=Suzuki%2CK&author=Matsubara%2CH bring in?
- How much income does https://doi.org/10.1016%2Fj.ymthe.2005.09.006 have?
- What's the revenue for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16226059?
- How much does http://scholar.google.com/scholar_lookup?&title=Spliceosome-mediated%20RNA%20trans-splicing&journal=Mol%20Ther&doi=10.1016%2Fj.ymthe.2005.09.006&volume=12&pages=1006-1012&publication_year=2005&author=Yang%2CY&author=Walsh%2CCE earn?
- How much profit does https://doi.org/10.1371%2Fjournal.pgen.0030109 make?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17604456 gross monthly?
- Learn how profitable http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904251 is on a monthly basis
- Income figures for http://scholar.google.com/scholar_lookup?&title=Modulating%20the%20expression%20of%20disease%20genes%20with%20RNA-based%20therapy&journal=PLoS%20Genet&doi=10.1371%2Fjournal.pgen.0030109&volume=3&publication_year=2007&author=Wood%2CM&author=Yin%2CH&author=McClorey%2CG
- What's the financial intake of https://doi.org/10.1016%2Fj.crvi.2004.05.008?
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15506518?
- How much does http://scholar.google.com/scholar_lookup?&title=Genetic%20medicine%20at%20the%20RNA%20level%3A%20modifications%20of%20the%20genetic%20repertoire%20for%20therapeutic%20purposes%20by%20pre-mRNA%20trans-splicing&journal=C%20R%20Biol&doi=10.1016%2Fj.crvi.2004.05.008&volume=327&pages=695-709&publication_year=2004&author=Pergolizzi%2CRG&author=Crystal%2CRG generate monthly?
- How much does https://doi.org/10.1038%2Fnrg1829 gross monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16543931 make?
- How much does http://scholar.google.com/scholar_lookup?&title=Genetic%20medicines%3A%20treatment%20strategies%20for%20hereditary%20disorders&journal=Nat%20Rev%20Genet&doi=10.1038%2Fnrg1829&volume=7&pages=261-276&publication_year=2006&author=O%27Connor%2CTP&author=Crystal%2CRG pull in?
- What's the income generated by https://doi.org/10.1016%2Fj.ccr.2012.03.042 each month?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22624712?
- How much income is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366694 earning monthly?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Allele-specific%20p53%20mutant%20reactivation&journal=Cancer%20cell&doi=10.1016%2Fj.ccr.2012.03.042&volume=21&pages=614-625&publication_year=2012&author=Yu%2CX&author=Vazquez%2CA&author=Levine%2CAJ&author=Carpizo%2CDR?
- Discover the revenue of https://doi.org/10.1016%2FS1470-2045%2809%2970198-6
- Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19717093
- How much revenue does http://scholar.google.com/scholar_lookup?&title=30%20years%20and%20a%20long%20way%20into%20p53%20research&journal=Lancet%20Oncol&doi=10.1016%2FS1470-2045%2809%2970198-6&volume=10&pages=913-919&publication_year=2009&author=Hainaut%2CP&author=Wiman%2CKG bring in?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20463003's revenue stream
- What's the financial intake of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926755?
- How much does http://scholar.google.com/scholar_lookup?&title=p53-based%20cancer%20therapy&journal=Cold%20Spring%20Harb%20Perspect%20Biol&volume=2&publication_year=2010&author=Lane%2CDP&author=Cheok%2CCF&author=Lain%2CS generate monthly?
- Get to know https://doi.org/10.1038%2Fnm0996-985's earnings
- Get to know what's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8782455
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Retrovirus-mediated%20wild-type%20p53%20gene%20transfer%20to%20tumors%20of%20patients%20with%20lung%20cancer&journal=Nat%20Med&doi=10.1038%2Fnm0996-985&volume=2&pages=985-991&publication_year=1996&author=Roth%2CJA produce monthly?
- https://doi.org/10.1126%2Fscience.314.5803.1232's financial summary
- How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17124300 have monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Chinese%20gene%20therapy.%20Splicing%20out%20the%20West%3F&journal=Science&doi=10.1126%2Fscience.314.5803.1232&volume=314&pages=1232-1235&publication_year=2006&author=Guo%2CJ&author=Xin%2CH net monthly?
- Earnings of https://doi.org/10.1111%2Fj.1349-7006.2006.00206.x
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16734736's financial summary
- How much profit is http://scholar.google.com/scholar_lookup?&title=Phase%20I%2FII%20adenoviral%20p53%20gene%20therapy%20for%20chemoradiation%20resistant%20advanced%20esophageal%20squamous%20cell%20carcinoma&journal=Cancer%20science&doi=10.1111%2Fj.1349-7006.2006.00206.x&volume=97&pages=554-561&publication_year=2006&author=Shimada%2CH making per month?
- How much revenue does https://doi.org/10.1101%2Fgad.1397506 bring in?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Unleashing%20the%20power%20of%20p53%3A%20lessons%20from%20mice%20and%20men&journal=Genes%20%26%20development&doi=10.1101%2Fgad.1397506&volume=20&pages=125-131&publication_year=2006&author=Poyurovsky%2CMV&author=Prives%2CC
- What's the financial gain of https://doi.org/10.1038%2Fnrc2731?
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19776746
- Monthly income for http://scholar.google.com/scholar_lookup?&title=20%20years%20studying%20p53%20functions%20in%20genetically%20engineered%20mice&journal=Nature%20reviews.%20Cancer&doi=10.1038%2Fnrc2731&volume=9&pages=831-841&publication_year=2009&author=Donehower%2CLA&author=Lozano%2CG
- https://doi.org/10.1038%2F415045a's financial summary
- What's the financial outcome of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2002Natur.415...45T?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11780111's total income per month
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=p53%20mutant%20mice%20that%20display%20early%20ageing-associated%20phenotypes&journal=Nature&doi=10.1038%2F415045a&volume=415&pages=45-53&publication_year=2002&author=Tyner%2CSD
- How much profit is https://doi.org/10.4161%2Fcc.7.12.6161 making per month?
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18594199's gross income?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Conditional%20RNA%20interference%20in%20vivo%20to%20study%20mutant%20p53%20oncogenic%20gain%20of%20function%20on%20tumor%20malignancy&journal=Cell%20Cycle&doi=10.4161%2Fcc.7.12.6161&volume=7&pages=1870-1879&publication_year=2008&author=Bossi%2CG
- What's the total monthly financial gain of https://link.springer.com/doi/10.1186/1477-7819-11-22?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23356234 income
- How much revenue does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565885 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Silencing%20of%20mutant%20p53%20by%20siRNA%20induces%20cell%20cycle%20arrest%20and%20apoptosis%20in%20human%20bladder%20cancer%20cells&journal=World%20journal%20of%20surgical%20oncology&doi=10.1186%2F1477-7819-11-22&volume=11&publication_year=2013&author=Zhu%2CHB bring in each month?
- What are the total earnings of https://doi.org/10.1038%2Fsj.onc.1209026?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16170357 make?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Mutant%20p53%20gain%20of%20function%3A%20reduction%20of%20tumor%20malignancy%20of%20human%20cancer%20cell%20lines%20through%20abrogation%20of%20mutant%20p53%20expression&journal=Oncogene&doi=10.1038%2Fsj.onc.1209026&volume=25&pages=304-309&publication_year=2006&author=Bossi%2CG
- Get to know https://doi.org/10.1073%2Fpnas.150104097's earnings
- http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2000PNAS...97.8490W's financial summary
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10890910?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC26975 make?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Induction%20of%20wild-type%20p53%20activity%20in%20human%20cancer%20cells%20by%20ribozymes%20that%20repair%20mutant%20p53%20transcripts&journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&doi=10.1073%2Fpnas.150104097&volume=97&pages=8490-8494&publication_year=2000&author=Watanabe%2CT&author=Sullenger%2CBA?
- How much profit does https://doi.org/10.1016%2Fj.ymthe.2004.05.007 generate?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15294183 net monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Ribozyme-mediated%20induction%20of%20apoptosis%20in%20human%20cancer%20cells%20by%20targeted%20repair%20of%20mutant%20p53%20RNA&journal=Mol%20Ther&doi=10.1016%2Fj.ymthe.2004.05.007&volume=10&pages=365-372&publication_year=2004&author=Shin%2CKS&author=Sullenger%2CBA&author=Lee%2CSW generate monthly?
- How much does https://doi.org/10.1038%2Fsj.gt.3301307 net monthly?
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11127576
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Repair%20of%20CFTR%20mRNA%20by%20spliceosome-mediated%20RNA%20trans-splicing&journal=Gene%20Ther&doi=10.1038%2Fsj.gt.3301307&volume=7&pages=1885-1895&publication_year=2000&author=Mansfield%2CSG?
- What's the monthly income of https://doi.org/10.1038%2Fnbt0102-47?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11753361 pull in monthly?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Partial%20correction%20of%20endogenous%20DeltaF508%20CFTR%20in%20human%20cystic%20fibrosis%20airway%20epithelia%20by%20spliceosome-mediated%20RNA%20trans-splicing&journal=Nat%20Biotechnol&doi=10.1038%2Fnbt0102-47&volume=20&pages=47-52&publication_year=2002&author=Liu%2CX?
- How much profit does https://doi.org/10.1038%2Fnm900 generate?
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12847523
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Phenotype%20correction%20of%20hemophilia%20A%20mice%20by%20spliceosome-mediated%20RNA%20trans-splicing&journal=Nat%20Med&doi=10.1038%2Fnm900&volume=9&pages=1015-1019&publication_year=2003&author=Chao%2CH
- Monthly income for https://doi.org/10.1038%2Fnm1086
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15273748 rake in every month?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Trans-splicing%20repair%20of%20CD40%20ligand%20deficiency%20results%20in%20naturally%20regulated%20correction%20of%20a%20mouse%20model%20of%20hyper-IgM%20X-linked%20immunodeficiency&journal=Nat%20Med&doi=10.1038%2Fnm1086&volume=10&pages=835-841&publication_year=2004&author=Tahara%2CM?
- How much does https://doi.org/10.1177%2F1947601911408893 earn?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=p53%20Isoforms%3A%20An%20Intracellular%20Microprocessor&journal=Genes%20%26%20cancer&doi=10.1177%2F1947601911408893&volume=2&pages=453-465&publication_year=2011&author=Khoury%2CMP&author=Bourdon%2CJC is on a monthly basis
- https://doi.org/10.1093%2Femboj%2Fcdf595's revenue stream
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12426394's total income per month
- What's the monthly income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137187?
- How much does http://scholar.google.com/scholar_lookup?&title=%E2%80%9CSuper%20p53%E2%80%9D%20mice%20exhibit%20enhanced%20DNA%20damage%20response%2C%20are%20tumor%20resistant%20and%20age%20normally&journal=The%20EMBO%20journal&doi=10.1093%2Femboj%2Fcdf595&volume=21&pages=6225-6235&publication_year=2002&author=Garcia-Cao%2CI earn?
- How much money does https://doi.org/10.1016%2Fj.bbadis.2014.01.016 generate?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24525025 income
- See how much http://scholar.google.com/scholar_lookup?&title=ARF%20tumor%20suppression%20in%20the%20nucleolus&journal=Biochimica%20et%20biophysica%20acta&doi=10.1016%2Fj.bbadis.2014.01.016&volume=1842&pages=831-839&publication_year=2014&author=Maggi%2CLB makes per month
- What are the earnings of https://doi.org/10.1101%2Fgad.827300?
- How much profit is http://scholar.google.com/scholar_lookup?&title=p53-independent%20functions%20of%20the%20p19%28ARF%29%20tumor%20suppressor&journal=Genes%20%26%20development&doi=10.1101%2Fgad.827300&volume=14&pages=2358-2365&publication_year=2000&author=Weber%2CJD making per month?
- How much money does https://link.springer.com/doi/10.1007/s00535-003-1302-9 make?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15168247?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Alteration%20of%20the%20p14%28ARF%29%20gene%20and%20p53%20status%20in%20human%20hepatocellular%20carcinomas&journal=Journal%20of%20gastroenterology&doi=10.1007%2Fs00535-003-1302-9&volume=39&pages=355-361&publication_year=2004&author=Ito%2CT?
- How much does https://link.springer.com/doi/10.1186/1471-2407-10-530 generate monthly?
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20923573's gross income?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978203 rake in every month?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Genetic%20and%20epigenetic%20characteristics%20of%20human%20multiple%20hepatocellular%20carcinoma&journal=BMC%20cancer&doi=10.1186%2F1471-2407-10-530&volume=10&publication_year=2010&author=Taniguchi%2CK&author=Yamada%2CT&author=Sasaki%2CY&author=Kato%2CK?
- https://doi.org/10.1038%2Fonc.2011.500's revenue stream
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22056881 is on a monthly basis
- How much does http://scholar.google.com/scholar_lookup?&title=MicroRNA-375%20targets%20AEG-1%20in%20hepatocellular%20carcinoma%20and%20suppresses%20liver%20cancer%20cell%20growth%20in%20vitro%20and%20in%20vivo&journal=Oncogene&doi=10.1038%2Fonc.2011.500&volume=31&pages=3357-3369&publication_year=2012&author=He%2CXX bring in each month?
- How much does https://doi.org/10.1111%2Fj.1582-4934.2011.01290.x gross monthly?
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21388516 generate?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Embryonic%20liver%20fodrin%20involved%20in%20hepatic%20stellate%20cell%20activation%20and%20formation%20of%20regenerative%20nodule%20in%20liver%20cirrhosis&journal=Journal%20of%20cellular%20and%20molecular%20medicine&doi=10.1111%2Fj.1582-4934.2011.01290.x&volume=16&pages=118-128&publication_year=2012&author=Wang%2CZ make?
- How much does https://doi.org/10.1111%2Fj.1478-3231.2012.02812.x bring in each month?
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22541060's gross income?
- http://scholar.google.com/scholar_lookup?&title=beta-2%20spectrin%20is%20involved%20in%20hepatocyte%20proliferation%20through%20the%20interaction%20of%20TGFbeta%2FSmad%20and%20PI3K%2FAKT%20signalling&journal=Liver%20international&doi=10.1111%2Fj.1478-3231.2012.02812.x&volume=32&pages=1103-1111&publication_year=2012&author=Wang%2CZ's financial summary
- How much revenue does https://citation-needed.springer.com/v2/references/10.1038/srep08705?format=refman&flavour=references bring in?
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Xingxing%20He's gross income?
- Discover the revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Xingxing%20He%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- Discover the revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Fang%20Liu
- Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Fang%20Liu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
- Monthly income for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jingjun%20Yan
- What's the financial outcome of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jingjun%20Yan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yunan%20Zhang?
- What are the total earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yunan%20Zhang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much revenue does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Junwei%20Yan generate?
- What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Junwei%20Yan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Haitao%20Shang's gross income?
- How much income is https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Haitao%20Shang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earning monthly?
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qian%20Dou's gross income?
- Learn how profitable https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qian%20Dou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en is on a monthly basis
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qiu%20Zhao pull in monthly?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qiu%20Zhao%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en net monthly?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yuhu%20Song's financial summary
- Get to know what's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yuhu%20Song%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- Profit of https://static-content.springer.com/esm/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_BFsrep08705_MOESM1_ESM.pdf
- What's the total monthly financial gain of http://creativecommons.org/licenses/by/4.0/?
- Profit of https://s100.copyright.com/AppDispatchServlet?title=Trans-splicing%20repair%20of%20mutant%20p53%20suppresses%20the%20growth%20of%20hepatocellular%20carcinoma%20cells%20in%20vitro%20and%20in%20vivo&author=Xingxing%20He%20et%20al&contentID=10.1038%2Fsrep08705©right=The%20Author%28s%29&publication=2045-2322&publicationDate=2015-03-03&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY
- Revenue of https://crossmark.crossref.org/dialog/?doi=10.1038/srep08705
- How much does https://citation-needed.springer.com/v2/references/10.1038/srep08705?format=refman&flavour=citation generate monthly?
- What are the total earnings of https://doi.org/10.1038/s41420-023-01312-5?
- See how much https://doi.org/10.1038/s41598-020-57854-6 makes per month
- Get to know https://doi.org/10.1038/s41375-018-0021-4's earnings
- How much does https://doi.org/10.1038/s41419-018-0456-6 earn?
- What's the income generated by https://doi.org/10.1186/s12885-017-3570-4 each month?
- Financial intake of https://www.protocols.io/
- How much income does https://www.natureindex.com/ have?
- What's the revenue for http://www.naturechina.com?
- What's the monthly income of https://www.natureasia.com/ja-jp?
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Prism.js
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {π¦}
- Crossref