
NATURE . COM {
}
Title:
Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo | Scientific Reports
Description:
Reactivation of wild-type p53 (wt-p53) function is an attractive therapeutic approach to p53-defective cancers. An ideal p53-based gene therapy should restore wt-p53 production and reduces mutant p53 transcripts simultaneously. In this study, we described an alternative strategy named as trans-splicing that repaired mutant p53 transcripts in hepatocellular carcinoma (HCC) cells. The plasmids which encoded a pre-trans-splicing molecule (PTM) targeting intron 6 of p53 were constructed and then transfected into HCC cells carrying p53 mutation. Phenotypic changes of HCC cells induced by p53-PTM were analyzed through cell cycle, cell apoptosis and the expression of p53 downstream target genes. Spliceosome mediated RNA trans-splicing (SMaRT) reduced mutant p53 transcripts and produced functional wt-p53 protein after the delivery of p53-PTM plasmids, which resulted in phenotype correction of HCC cells. In tumor xenografts established by p53-mutated HCC cells, adenovirus encoding p53-PTM induced cell cycle arrest and apoptosis and then blocked the growth of tumors in mice. Collectively, our results demonstrated for the first time that mutant p53 transcripts were functionally corrected in p53-defective HCC cells and xenografts using trans-splicing, which indicated the feasibility of using trans-splicing to repair p53 mutation in p53-defective cancers.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Science
- Education
- Telecommunications
Content Management System {π}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of nature.com audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {πΈ}
Display Ads {π―}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
Display Ads {π―}
$63,100 per month
Our calculations suggest that Nature.com earns between $42,042 and $115,616 monthly online from display advertisements.
Keywords {π}
cells, mutant, article, pubmed, cancer, google, scholar, cell, hcc, cas, transcripts, plcprf, pptm, transsplicing, expression, tumor, figure, wtp, repair, tumors, growth, apoptosis, genes, transfected, nature, gene, mutation, cycle, smart, human, rna, mice, adenovirus, hepatocellular, carcinoma, demonstrated, genetic, xenograft, pdefective, study, mutations, liver, rtpcr, central, function, protein, correction, supplementary, vitro, therapy,
Topics {βοΈ}
nature portfolio privacy policy providing pcmv-neo-bam wtp53 plasmid pcmv-neo-bam wtp53 hyper-igm x-linked immunodeficiency advertising diverse nature spliceosome-mediated rna trans-splicing nature reviews evaluate trans-splicing-mediated repair p53 pre-trans-splicing molecules nature 415 nature p53-ptm-e7-11 trans-activated social media trans-splicing ribozymes-mediate repair ad-p53ptm-e7-11 group manifested pre-established plc/prf/5 xenografts trans-spliced p53 rnas 0/ reprints adenovirus encoding p53-ptm p53 research p53-based cancer therapies trans-spliced p53 rna vectors expressing p53-ptm italy trans splicing-mediated revision pre-trans-splicing molecule providing pcyclinb-prom-luc pre-mrna trans-splicing wild-type p53 activity trans-splicing-mediated repair plasmid carrying p53-ptm wild-type human p53 trans-activate downstream genes sybr green qrt-pcr p53-dependent downstream genes restores wt-p53 activity defective target pre-mrna restored wt-p53 activities mature wt-p53 transcripts activating cyclin-dependent kinase blocking mdm2-induced degradation yeast branch-point consensus wild-type p53 function restore wt-p53 production p53-dependent target genes plc/prf/5 cells led induces wt-p53 production research
Questions {β}
- Splicing out the West?
- P53 Isoforms: An Intracellular Microprocessor?
- P53-based cancer therapies: Is defective p53 the Achilles heel of the tumor?
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo
description:Reactivation of wild-type p53 (wt-p53) function is an attractive therapeutic approach to p53-defective cancers. An ideal p53-based gene therapy should restore wt-p53 production and reduces mutant p53 transcripts simultaneously. In this study, we described an alternative strategy named as trans-splicing that repaired mutant p53 transcripts in hepatocellular carcinoma (HCC) cells. The plasmids which encoded a pre-trans-splicing molecule (PTM) targeting intron 6 of p53 were constructed and then transfected into HCC cells carrying p53 mutation. Phenotypic changes of HCC cells induced by p53-PTM were analyzed through cell cycle, cell apoptosis and the expression of p53 downstream target genes. Spliceosome mediated RNA trans-splicing (SMaRT) reduced mutant p53 transcripts and produced functional wt-p53 protein after the delivery of p53-PTM plasmids, which resulted in phenotype correction of HCC cells. In tumor xenografts established by p53-mutated HCC cells, adenovirus encoding p53-PTM induced cell cycle arrest and apoptosis and then blocked the growth of tumors in mice. Collectively, our results demonstrated for the first time that mutant p53 transcripts were functionally corrected in p53-defective HCC cells and xenografts using trans-splicing, which indicated the feasibility of using trans-splicing to repair p53 mutation in p53-defective cancers.
datePublished:2015-03-03T00:00:00Z
dateModified:2015-03-03T00:00:00Z
pageStart:1
pageEnd:8
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/srep08705
keywords:
Targeted therapies
Translational research
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig4_HTML.jpg
isPartOf:
name:Scientific Reports
issn:
2045-2322
volumeNumber:5
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Xingxing He
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Fang Liu
affiliation:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Jingjun Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yunan Zhang
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Junwei Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Haitao Shang
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qian Dou
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qiu Zhao
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yuhu Song
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:Trans-splicing repair of mutant p53 suppresses the growth of hepatocellular carcinoma cells in vitro and in vivo
description:Reactivation of wild-type p53 (wt-p53) function is an attractive therapeutic approach to p53-defective cancers. An ideal p53-based gene therapy should restore wt-p53 production and reduces mutant p53 transcripts simultaneously. In this study, we described an alternative strategy named as trans-splicing that repaired mutant p53 transcripts in hepatocellular carcinoma (HCC) cells. The plasmids which encoded a pre-trans-splicing molecule (PTM) targeting intron 6 of p53 were constructed and then transfected into HCC cells carrying p53 mutation. Phenotypic changes of HCC cells induced by p53-PTM were analyzed through cell cycle, cell apoptosis and the expression of p53 downstream target genes. Spliceosome mediated RNA trans-splicing (SMaRT) reduced mutant p53 transcripts and produced functional wt-p53 protein after the delivery of p53-PTM plasmids, which resulted in phenotype correction of HCC cells. In tumor xenografts established by p53-mutated HCC cells, adenovirus encoding p53-PTM induced cell cycle arrest and apoptosis and then blocked the growth of tumors in mice. Collectively, our results demonstrated for the first time that mutant p53 transcripts were functionally corrected in p53-defective HCC cells and xenografts using trans-splicing, which indicated the feasibility of using trans-splicing to repair p53 mutation in p53-defective cancers.
datePublished:2015-03-03T00:00:00Z
dateModified:2015-03-03T00:00:00Z
pageStart:1
pageEnd:8
license:http://creativecommons.org/licenses/by/4.0/
sameAs:https://doi.org/10.1038/srep08705
keywords:
Targeted therapies
Translational research
Science
Humanities and Social Sciences
multidisciplinary
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_Article_BFsrep08705_Fig4_HTML.jpg
isPartOf:
name:Scientific Reports
issn:
2045-2322
volumeNumber:5
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:Xingxing He
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Fang Liu
affiliation:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Jingjun Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yunan Zhang
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Junwei Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Haitao Shang
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qian Dou
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Qiu Zhao
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
name:Yuhu Song
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
type:Person
isAccessibleForFree:1
["Periodical","PublicationVolume"]:
name:Scientific Reports
issn:
2045-2322
volumeNumber:5
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:Xingxing He
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Fang Liu
affiliation:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Jingjun Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Yunan Zhang
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Junwei Yan
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Haitao Shang
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Qian Dou
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Qiu Zhao
affiliation:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
name:Yuhu Song
affiliation:
name:Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
address:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
type:PostalAddress
type:Organization
PostalAddress:
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Institute of Liver Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
name:Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China
External Links {π}(192)
- Check the income stats for http://publications.cancerresearchuk.org/downloads/Product/CS_INFOG_WORLD_MORT.PDF
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Global%20cancer%20statistics&journal=CA%3A%20a%20cancer%20journal%20for%20clinicians&volume=61&pages=69-90&publication_year=2011&author=Jemal%2CA?
- What's the profit of https://doi.org/10.1002%2Fhep.20933?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16250051 generate monthly?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Management%20of%20hepatocellular%20carcinoma&journal=Hepatology&doi=10.1002%2Fhep.20933&volume=42&pages=1208-1236&publication_year=2005&author=Bruix%2CJ&author=Sherman%2CM
- What's the total monthly financial gain of https://doi.org/10.1016%2Fj.jhep.2009.11.015?
- What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20022654?
- http://scholar.google.com/scholar_lookup?&title=Risk%20of%20HCC%3A%20genetic%20heterogeneity%20and%20complex%20genetics&journal=Journal%20of%20hepatology&doi=10.1016%2Fj.jhep.2009.11.015&volume=52&pages=252-257&publication_year=2010&author=Dragani%2CTA's total income per month
- What is the monthly revenue of https://doi.org/10.1016%2FS0168-8278%2812%2960009-9?
- Discover the revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22300468
- Profit of http://scholar.google.com/scholar_lookup?&title=Management%20of%20HCC&journal=Journal%20of%20hepatology&doi=10.1016%2FS0168-8278%2812%2960009-9&volume=56&pages=S75-87&publication_year=2012&author=de%20Lope%2CCR&author=Tremosini%2CS&author=Forner%2CA&author=Reig%2CM&author=Bruix%2CJ
- Find out how much https://doi.org/10.3748%2Fwjg.14.1720 earns monthly
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18350603?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695912 make?
- Income figures for http://scholar.google.com/scholar_lookup?&title=Tumor%20suppressor%20and%20hepatocellular%20carcinoma&journal=World%20J%20Gastroenterol&doi=10.3748%2Fwjg.14.1720&volume=14&pages=1720-1733&publication_year=2008&author=Martin%2CJ&author=Dufour%2CJF
- https://doi.org/10.1101%2Fcshperspect.a001115's revenue stream
- See how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20452944 makes per month
- What's the revenue for http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845198?
- What's http://scholar.google.com/scholar_lookup?&title=Mouse%20models%20of%20p53%20functions&journal=Cold%20Spring%20Harb%20Perspect%20Biol&doi=10.1101%2Fcshperspect.a001115&volume=2&publication_year=2010&author=Lozano%2CG's gross income?
- How much profit is https://doi.org/10.1056%2FNEJMp0707422 making per month?
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18094374's gross income?
- Income figures for http://scholar.google.com/scholar_lookup?&title=p53-master%20and%20commander&journal=N%20Engl%20J%20Med&doi=10.1056%2FNEJMp0707422&volume=357&pages=2539-2541&publication_year=2007&author=Foulkes%2CWD
- Earnings of https://doi.org/10.1016%2Fj.cell.2009.04.050
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19450511 income
- What's the income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737742?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Modes%20of%20p53%20regulation&journal=Cell&doi=10.1016%2Fj.cell.2009.04.050&volume=137&pages=609-622&publication_year=2009&author=Kruse%2CJP&author=Gu%2CW have monthly?
- How much does https://doi.org/10.1038%2Fncb2641 generate monthly?
- Learn how profitable http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23263379 is on a monthly basis
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=p53%20mutations%20in%20cancer&journal=Nature%20cell%20biology&doi=10.1038%2Fncb2641&volume=15&pages=2-8&publication_year=2013&author=Muller%2CPA&author=Vousden%2CKH?
- What are the earnings of https://doi.org/10.1002%2Fpath.2784?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21125670 bring in each month?
- How much money does http://scholar.google.com/scholar_lookup?&title=The%20role%20of%20mutant%20p53%20in%20human%20cancer&journal=The%20Journal%20of%20pathology&doi=10.1002%2Fpath.2784&volume=223&pages=116-126&publication_year=2011&author=Goh%2CAM&author=Coffill%2CCR&author=Lane%2CDP generate?
- How profitable is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=14633666?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Mouse%20models%20to%20study%20the%20interaction%20of%20risk%20factors%20for%20human%20liver%20cancer&journal=Cancer%20Res&volume=63&pages=7553-7562&publication_year=2003&author=Sell%2CS is on a monthly basis
- How much cash flow does https://doi.org/10.1002%2Fhep.22580 have monthly?
- What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19003900?
- See how much http://scholar.google.com/scholar_lookup?&title=Molecular%20mechanisms%20of%20hepatocellular%20carcinoma&journal=Hepatology&doi=10.1002%2Fhep.22580&volume=48&pages=2047-2063&publication_year=2008&author=Aravalli%2CRN&author=Steer%2CCJ&author=Cressman%2CEN makes per month
- How much does https://doi.org/10.1016%2Fj.ejca.2012.03.001 make?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22459764?
- What are the total earnings of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395767?
- How much income is http://scholar.google.com/scholar_lookup?&title=Alterations%20of%20TP53%20are%20associated%20with%20a%20poor%20outcome%20for%20patients%20with%20hepatocellular%20carcinoma%3A%20evidence%20from%20a%20systematic%20review%20and%20meta-analysis&journal=Eur%20J%20Cancer&doi=10.1016%2Fj.ejca.2012.03.001&volume=48&pages=2328-2338&publication_year=2012&author=Liu%2CJ earning monthly?
- Income figures for https://doi.org/10.1038%2Fsj.onc.1210291
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17401432?
- How much does http://scholar.google.com/scholar_lookup?&title=Structure-function-rescue%3A%20the%20diverse%20nature%20of%20common%20p53%20cancer%20mutants&journal=Oncogene&doi=10.1038%2Fsj.onc.1210291&volume=26&pages=2226-2242&publication_year=2007&author=Joerger%2CAC&author=Fersht%2CAR rake in every month?
- https://doi.org/10.1101%2Fgad.190678.112's financial summary
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Mutant%20p53%3A%20one%20name%2C%20many%20proteins&journal=Genes%20%26%20development&doi=10.1101%2Fgad.190678.112&volume=26&pages=1268-1286&publication_year=2012&author=Freed-Pastor%2CWA&author=Prives%2CC
- How much does https://doi.org/10.1002%2Fhed.20529 net monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17230559 gross monthly?
- How much income is http://scholar.google.com/scholar_lookup?&title=Restoration%20of%20wild-type%20p53%20function%20in%20human%20cancer%3A%20relevance%20for%20tumor%20therapy&journal=Head%20Neck&doi=10.1002%2Fhed.20529&volume=29&pages=272-284&publication_year=2007&author=Bossi%2CG&author=Sacchi%2CA earning monthly?
- What's the income of https://doi.org/10.1038%2Fsj.onc.1210295?
- What's http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17401433's gross income?
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Reactivation%20of%20mutant%20p53%3A%20molecular%20mechanisms%20and%20therapeutic%20potential&journal=Oncogene&doi=10.1038%2Fsj.onc.1210295&volume=26&pages=2243-2254&publication_year=2007&author=Selivanova%2CG&author=Wiman%2CKG
- Financial intake of https://doi.org/10.1038%2Fnrclinonc.2010.174
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20975744 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Translating%20p53%20into%20the%20clinic&journal=Nature%20reviews.%20Clinical%20oncology&doi=10.1038%2Fnrclinonc.2010.174&volume=8&pages=25-37&publication_year=2011&author=Cheok%2CCF&author=Verma%2CCS&author=Baselga%2CJ&author=Lane%2CDP generate monthly?
- What's https://doi.org/10.1093%2Fcarcin%2Fbgl214's gross income?
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17088261
- Monthly income for http://scholar.google.com/scholar_lookup?&title=p53-based%20cancer%20therapies%3A%20Is%20defective%20p53%20the%20Achilles%20heel%20of%20the%20tumor&journal=Carcinogenesis&doi=10.1093%2Fcarcin%2Fbgl214&volume=28&pages=13-20&publication_year=2007&author=Levesque%2CAA&author=Eastman%2CA
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21765642 make?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134396 make?
- How much does http://scholar.google.com/scholar_lookup?&title=Recent%20advances%20in%20p53%20research%20and%20cancer%20treatment&journal=J%20Biomed%20Biotechnol&volume=2011&publication_year=2011&author=Suzuki%2CK&author=Matsubara%2CH make?
- How much does https://doi.org/10.1016%2Fj.ymthe.2005.09.006 rake in every month?
- Earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16226059
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Spliceosome-mediated%20RNA%20trans-splicing&journal=Mol%20Ther&doi=10.1016%2Fj.ymthe.2005.09.006&volume=12&pages=1006-1012&publication_year=2005&author=Yang%2CY&author=Walsh%2CCE generate?
- Find out how much https://doi.org/10.1371%2Fjournal.pgen.0030109 earns monthly
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17604456?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904251?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Modulating%20the%20expression%20of%20disease%20genes%20with%20RNA-based%20therapy&journal=PLoS%20Genet&doi=10.1371%2Fjournal.pgen.0030109&volume=3&publication_year=2007&author=Wood%2CM&author=Yin%2CH&author=McClorey%2CG earns monthly
- How much does https://doi.org/10.1016%2Fj.crvi.2004.05.008 pull in?
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15506518
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Genetic%20medicine%20at%20the%20RNA%20level%3A%20modifications%20of%20the%20genetic%20repertoire%20for%20therapeutic%20purposes%20by%20pre-mRNA%20trans-splicing&journal=C%20R%20Biol&doi=10.1016%2Fj.crvi.2004.05.008&volume=327&pages=695-709&publication_year=2004&author=Pergolizzi%2CRG&author=Crystal%2CRG?
- See how much https://doi.org/10.1038%2Fnrg1829 makes per month
- Profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16543931
- How much does http://scholar.google.com/scholar_lookup?&title=Genetic%20medicines%3A%20treatment%20strategies%20for%20hereditary%20disorders&journal=Nat%20Rev%20Genet&doi=10.1038%2Fnrg1829&volume=7&pages=261-276&publication_year=2006&author=O%27Connor%2CTP&author=Crystal%2CRG gross monthly?
- https://doi.org/10.1016%2Fj.ccr.2012.03.042's total income per month
- Explore the financials of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22624712
- How much profit does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366694 make?
- http://scholar.google.com/scholar_lookup?&title=Allele-specific%20p53%20mutant%20reactivation&journal=Cancer%20cell&doi=10.1016%2Fj.ccr.2012.03.042&volume=21&pages=614-625&publication_year=2012&author=Yu%2CX&author=Vazquez%2CA&author=Levine%2CAJ&author=Carpizo%2CDR's revenue stream
- Revenue of https://doi.org/10.1016%2FS1470-2045%2809%2970198-6
- Get to know http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19717093's earnings
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=30%20years%20and%20a%20long%20way%20into%20p53%20research&journal=Lancet%20Oncol&doi=10.1016%2FS1470-2045%2809%2970198-6&volume=10&pages=913-919&publication_year=2009&author=Hainaut%2CP&author=Wiman%2CKG is on a monthly basis
- What's the revenue for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20463003?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926755 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=p53-based%20cancer%20therapy&journal=Cold%20Spring%20Harb%20Perspect%20Biol&volume=2&publication_year=2010&author=Lane%2CDP&author=Cheok%2CCF&author=Lain%2CS net monthly?
- How much money does https://doi.org/10.1038%2Fnm0996-985 generate?
- What's the income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8782455?
- See how much http://scholar.google.com/scholar_lookup?&title=Retrovirus-mediated%20wild-type%20p53%20gene%20transfer%20to%20tumors%20of%20patients%20with%20lung%20cancer&journal=Nat%20Med&doi=10.1038%2Fnm0996-985&volume=2&pages=985-991&publication_year=1996&author=Roth%2CJA makes per month
- Find out how much https://doi.org/10.1126%2Fscience.314.5803.1232 earns monthly
- How much revenue does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17124300 bring in?
- Discover the revenue of http://scholar.google.com/scholar_lookup?&title=Chinese%20gene%20therapy.%20Splicing%20out%20the%20West%3F&journal=Science&doi=10.1126%2Fscience.314.5803.1232&volume=314&pages=1232-1235&publication_year=2006&author=Guo%2CJ&author=Xin%2CH
- What are the total earnings of https://doi.org/10.1111%2Fj.1349-7006.2006.00206.x?
- What's the financial intake of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16734736?
- How much does http://scholar.google.com/scholar_lookup?&title=Phase%20I%2FII%20adenoviral%20p53%20gene%20therapy%20for%20chemoradiation%20resistant%20advanced%20esophageal%20squamous%20cell%20carcinoma&journal=Cancer%20science&doi=10.1111%2Fj.1349-7006.2006.00206.x&volume=97&pages=554-561&publication_year=2006&author=Shimada%2CH rake in every month?
- https://doi.org/10.1101%2Fgad.1397506's revenue stream
- How much does http://scholar.google.com/scholar_lookup?&title=Unleashing%20the%20power%20of%20p53%3A%20lessons%20from%20mice%20and%20men&journal=Genes%20%26%20development&doi=10.1101%2Fgad.1397506&volume=20&pages=125-131&publication_year=2006&author=Poyurovsky%2CMV&author=Prives%2CC pull in?
- What's the monthly income of https://doi.org/10.1038%2Fnrc2731?
- Find out how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=19776746 earns monthly
- How much does http://scholar.google.com/scholar_lookup?&title=20%20years%20studying%20p53%20functions%20in%20genetically%20engineered%20mice&journal=Nature%20reviews.%20Cancer&doi=10.1038%2Fnrc2731&volume=9&pages=831-841&publication_year=2009&author=Donehower%2CLA&author=Lozano%2CG gross monthly?
- How much money does https://doi.org/10.1038%2F415045a make?
- How much does http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2002Natur.415...45T bring in each month?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11780111 rake in every month?
- How much does http://scholar.google.com/scholar_lookup?&title=p53%20mutant%20mice%20that%20display%20early%20ageing-associated%20phenotypes&journal=Nature&doi=10.1038%2F415045a&volume=415&pages=45-53&publication_year=2002&author=Tyner%2CSD rake in every month?
- What's the monthly money flow for https://doi.org/10.4161%2Fcc.7.12.6161?
- Find out how much http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=18594199 earns monthly
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Conditional%20RNA%20interference%20in%20vivo%20to%20study%20mutant%20p53%20oncogenic%20gain%20of%20function%20on%20tumor%20malignancy&journal=Cell%20Cycle&doi=10.4161%2Fcc.7.12.6161&volume=7&pages=1870-1879&publication_year=2008&author=Bossi%2CG?
- How much profit does https://link.springer.com/doi/10.1186/1477-7819-11-22 make?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23356234 pull in monthly?
- How much income is http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565885 earning monthly?
- Get to know what's the income of http://scholar.google.com/scholar_lookup?&title=Silencing%20of%20mutant%20p53%20by%20siRNA%20induces%20cell%20cycle%20arrest%20and%20apoptosis%20in%20human%20bladder%20cancer%20cells&journal=World%20journal%20of%20surgical%20oncology&doi=10.1186%2F1477-7819-11-22&volume=11&publication_year=2013&author=Zhu%2CHB
- What's the profit of https://doi.org/10.1038%2Fsj.onc.1209026?
- What's the profit of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16170357?
- http://scholar.google.com/scholar_lookup?&title=Mutant%20p53%20gain%20of%20function%3A%20reduction%20of%20tumor%20malignancy%20of%20human%20cancer%20cell%20lines%20through%20abrogation%20of%20mutant%20p53%20expression&journal=Oncogene&doi=10.1038%2Fsj.onc.1209026&volume=25&pages=304-309&publication_year=2006&author=Bossi%2CG income
- Financial intake of https://doi.org/10.1073%2Fpnas.150104097
- What is the earnings of http://adsabs.harvard.edu/cgi-bin/nph-data_query?link_type=ABSTRACT&bibcode=2000PNAS...97.8490W?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10890910 rake in every month?
- How much does http://www.ncbi.nlm.nih.gov/pmc/articles/PMC26975 bring in each month?
- http://scholar.google.com/scholar_lookup?&title=Induction%20of%20wild-type%20p53%20activity%20in%20human%20cancer%20cells%20by%20ribozymes%20that%20repair%20mutant%20p53%20transcripts&journal=Proc%20Natl%20Acad%20Sci%20U%20S%20A&doi=10.1073%2Fpnas.150104097&volume=97&pages=8490-8494&publication_year=2000&author=Watanabe%2CT&author=Sullenger%2CBA's revenue stream
- Income figures for https://doi.org/10.1016%2Fj.ymthe.2004.05.007
- How much profit does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15294183 make?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Ribozyme-mediated%20induction%20of%20apoptosis%20in%20human%20cancer%20cells%20by%20targeted%20repair%20of%20mutant%20p53%20RNA&journal=Mol%20Ther&doi=10.1016%2Fj.ymthe.2004.05.007&volume=10&pages=365-372&publication_year=2004&author=Shin%2CKS&author=Sullenger%2CBA&author=Lee%2CSW is on a monthly basis
- What's the monthly money flow for https://doi.org/10.1038%2Fsj.gt.3301307?
- How much money does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11127576 generate?
- http://scholar.google.com/scholar_lookup?&title=Repair%20of%20CFTR%20mRNA%20by%20spliceosome-mediated%20RNA%20trans-splicing&journal=Gene%20Ther&doi=10.1038%2Fsj.gt.3301307&volume=7&pages=1885-1895&publication_year=2000&author=Mansfield%2CSG's total income per month
- Profit of https://doi.org/10.1038%2Fnbt0102-47
- How much profit is http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11753361 making per month?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Partial%20correction%20of%20endogenous%20DeltaF508%20CFTR%20in%20human%20cystic%20fibrosis%20airway%20epithelia%20by%20spliceosome-mediated%20RNA%20trans-splicing&journal=Nat%20Biotechnol&doi=10.1038%2Fnbt0102-47&volume=20&pages=47-52&publication_year=2002&author=Liu%2CX generate?
- How much money does https://doi.org/10.1038%2Fnm900 generate?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12847523 pull in monthly?
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=Phenotype%20correction%20of%20hemophilia%20A%20mice%20by%20spliceosome-mediated%20RNA%20trans-splicing&journal=Nat%20Med&doi=10.1038%2Fnm900&volume=9&pages=1015-1019&publication_year=2003&author=Chao%2CH?
- What's the monthly income of https://doi.org/10.1038%2Fnm1086?
- Monthly income for http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15273748
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Trans-splicing%20repair%20of%20CD40%20ligand%20deficiency%20results%20in%20naturally%20regulated%20correction%20of%20a%20mouse%20model%20of%20hyper-IgM%20X-linked%20immunodeficiency&journal=Nat%20Med&doi=10.1038%2Fnm1086&volume=10&pages=835-841&publication_year=2004&author=Tahara%2CM
- Learn about the earnings of https://doi.org/10.1177%2F1947601911408893
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=p53%20Isoforms%3A%20An%20Intracellular%20Microprocessor&journal=Genes%20%26%20cancer&doi=10.1177%2F1947601911408893&volume=2&pages=453-465&publication_year=2011&author=Khoury%2CMP&author=Bourdon%2CJC each month?
- See how much https://doi.org/10.1093%2Femboj%2Fcdf595 makes per month
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12426394?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137187?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=%E2%80%9CSuper%20p53%E2%80%9D%20mice%20exhibit%20enhanced%20DNA%20damage%20response%2C%20are%20tumor%20resistant%20and%20age%20normally&journal=The%20EMBO%20journal&doi=10.1093%2Femboj%2Fcdf595&volume=21&pages=6225-6235&publication_year=2002&author=Garcia-Cao%2CI
- Check the income stats for https://doi.org/10.1016%2Fj.bbadis.2014.01.016
- How much cash flow does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=24525025 have monthly?
- See how much http://scholar.google.com/scholar_lookup?&title=ARF%20tumor%20suppression%20in%20the%20nucleolus&journal=Biochimica%20et%20biophysica%20acta&doi=10.1016%2Fj.bbadis.2014.01.016&volume=1842&pages=831-839&publication_year=2014&author=Maggi%2CLB makes per month
- Earnings of https://doi.org/10.1101%2Fgad.827300
- How much does http://scholar.google.com/scholar_lookup?&title=p53-independent%20functions%20of%20the%20p19%28ARF%29%20tumor%20suppressor&journal=Genes%20%26%20development&doi=10.1101%2Fgad.827300&volume=14&pages=2358-2365&publication_year=2000&author=Weber%2CJD net monthly?
- https://link.springer.com/doi/10.1007/s00535-003-1302-9's revenue stream
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15168247?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=Alteration%20of%20the%20p14%28ARF%29%20gene%20and%20p53%20status%20in%20human%20hepatocellular%20carcinomas&journal=Journal%20of%20gastroenterology&doi=10.1007%2Fs00535-003-1302-9&volume=39&pages=355-361&publication_year=2004&author=Ito%2CT?
- How much does https://link.springer.com/doi/10.1186/1471-2407-10-530 pull in monthly?
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20923573
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978203 income
- Earnings of http://scholar.google.com/scholar_lookup?&title=Genetic%20and%20epigenetic%20characteristics%20of%20human%20multiple%20hepatocellular%20carcinoma&journal=BMC%20cancer&doi=10.1186%2F1471-2407-10-530&volume=10&publication_year=2010&author=Taniguchi%2CK&author=Yamada%2CT&author=Sasaki%2CY&author=Kato%2CK
- How much profit is https://doi.org/10.1038%2Fonc.2011.500 making per month?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22056881 bring in each month?
- How much does http://scholar.google.com/scholar_lookup?&title=MicroRNA-375%20targets%20AEG-1%20in%20hepatocellular%20carcinoma%20and%20suppresses%20liver%20cancer%20cell%20growth%20in%20vitro%20and%20in%20vivo&journal=Oncogene&doi=10.1038%2Fonc.2011.500&volume=31&pages=3357-3369&publication_year=2012&author=He%2CXX bring in each month?
- How much does https://doi.org/10.1111%2Fj.1582-4934.2011.01290.x pull in monthly?
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=21388516 earn?
- How much does http://scholar.google.com/scholar_lookup?&title=Embryonic%20liver%20fodrin%20involved%20in%20hepatic%20stellate%20cell%20activation%20and%20formation%20of%20regenerative%20nodule%20in%20liver%20cirrhosis&journal=Journal%20of%20cellular%20and%20molecular%20medicine&doi=10.1111%2Fj.1582-4934.2011.01290.x&volume=16&pages=118-128&publication_year=2012&author=Wang%2CZ pull in?
- What's the monthly income of https://doi.org/10.1111%2Fj.1478-3231.2012.02812.x?
- What's the monthly income of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=22541060?
- What's the financial gain of http://scholar.google.com/scholar_lookup?&title=beta-2%20spectrin%20is%20involved%20in%20hepatocyte%20proliferation%20through%20the%20interaction%20of%20TGFbeta%2FSmad%20and%20PI3K%2FAKT%20signalling&journal=Liver%20international&doi=10.1111%2Fj.1478-3231.2012.02812.x&volume=32&pages=1103-1111&publication_year=2012&author=Wang%2CZ?
- What's the financial gain of https://citation-needed.springer.com/v2/references/10.1038/srep08705?format=refman&flavour=references?
- How much money does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Xingxing%20He generate?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Xingxing%20He%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en earn?
- Find out how much https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Fang%20Liu earns monthly
- What's the total monthly financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Fang%20Liu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the total monthly financial gain of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jingjun%20Yan?
- How much income does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jingjun%20Yan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en have?
- What are the earnings of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yunan%20Zhang?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yunan%20Zhang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en bring in each month?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Junwei%20Yan earn?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Junwei%20Yan%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in monthly?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Haitao%20Shang earn?
- What are the earnings of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Haitao%20Shang%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qian%20Dou pull in monthly?
- What's the income generated by https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qian%20Dou%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en each month?
- https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Qiu%20Zhao income
- https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Qiu%20Zhao%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's total income per month
- What's https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Yuhu%20Song's gross income?
- How much profit does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Yuhu%20Song%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en generate?
- How much money does https://static-content.springer.com/esm/art%3A10.1038%2Fsrep08705/MediaObjects/41598_2015_BFsrep08705_MOESM1_ESM.pdf generate?
- What's the income generated by http://creativecommons.org/licenses/by/4.0/ each month?
- Revenue of https://s100.copyright.com/AppDispatchServlet?title=Trans-splicing%20repair%20of%20mutant%20p53%20suppresses%20the%20growth%20of%20hepatocellular%20carcinoma%20cells%20in%20vitro%20and%20in%20vivo&author=Xingxing%20He%20et%20al&contentID=10.1038%2Fsrep08705©right=The%20Author%28s%29&publication=2045-2322&publicationDate=2015-03-03&publisherName=SpringerNature&orderBeanReset=true&oa=CC%20BY
- What is the monthly revenue of https://crossmark.crossref.org/dialog/?doi=10.1038/srep08705?
- How much revenue does https://citation-needed.springer.com/v2/references/10.1038/srep08705?format=refman&flavour=citation bring in?
- Get to know https://doi.org/10.1038/s41420-023-01312-5's earnings
- What's the income of https://doi.org/10.1038/s41598-020-57854-6?
- What's https://doi.org/10.1038/s41375-018-0021-4's gross income?
- How much revenue does https://doi.org/10.1038/s41419-018-0456-6 produce monthly?
- How much does https://doi.org/10.1186/s12885-017-3570-4 pull in?
- What are the earnings of https://www.protocols.io/?
- https://www.natureindex.com/'s total income per month
- http://www.naturechina.com's total income per month
- How much does https://www.natureasia.com/ja-jp make?
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Prism.js
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {π¦}
- Crossref