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Title:
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition | Oncogene
Description:
The term mitochondrial permeability transition (MPT) is commonly used to indicate an abrupt increase in the permeability of the inner mitochondrial membrane to low molecular weight solutes. Widespread MPT has catastrophic consequences for the cell, de facto marking the boundary between cellular life and death. MPT results indeed in the structural and functional collapse of mitochondria, an event that commits cells to suicide via regulated necrosis or apoptosis. MPT has a central role in the etiology of both acute and chronic diseases characterized by the loss of post-mitotic cells. Moreover, cancer cells are often relatively insensitive to the induction of MPT, underlying their increased resistance to potentially lethal cues. Thus, intense efforts have been dedicated not only at the understanding of MPT in mechanistic terms, but also at the development of pharmacological MPT modulators. In this setting, multiple mitochondrial and extramitochondrial proteins have been suspected to critically regulate the MPT. So far, however, only peptidylprolyl isomerase F (best known as cyclophilin D) appears to constitute a key component of the so-called permeability transition pore complex (PTPC), the supramolecular entity that is believed to mediate MPT. Here, after reviewing the structural and functional features of the PTPC, we summarize recent findings suggesting that another of its core components is represented by the c subunit of mitochondrial ATP synthase.
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nature portfolio permissions reprints privacy policy gsk-3beta-mediated myocardial protection advertising atp/adp-mediated matrix ca siric cancer research social media autophagy-inflammation-cell death axis cancer research institutes glycogen synthase kinase-3beta voltage-dependent anion channel voltage-dependent anion channels european research council mg2+-induced adp-dependent inhibition development protect pancreatic beta-cells italy active/inactive state transitions slow active/inactive transition induced large-amplitude swelling reverses bcl-2-mediated cytoprotection ca2+-dependent cell survival reversible antiport-uniport conversion cancer research bid-induced conformational change mitochondrial f1f0-atp synthase matrix substrate-level phosphorylation mitochondrial f1f0-atp synthases nature 2009 nature 2011 nature 2005 nature 2004 nature 1999 nature 1961 nature 1997 nature 2013 nature 1981 nature 2006 nature peripheral-type benzodiazepine receptor ameliorate cardio-apoptotic risks mitochondrial-dependent cell death cgmp-dependent protein kinase anti-apoptotic mcl-1 localizes cytokine-induced cell death phosphate-induced mitochondrial swelling acetaminophen-induced oxidant stress potentiates chemotherapy-induced cytotoxicity anti-apoptotic bcl-2 proteins
Questions {❓}
- Is supercomplex organization of the respiratory chain required for optimal electron transfer activity?
- Modulation of the mitochondrial permeability transition by cyclophilin D: moving closer to F(0)-F(1) ATP synthase?
- The apoptotic pore on mitochondria: are we breaking through or still stuck?
- What is the mitochondrial permeability transition pore?
- What makes you can also break you, part II: mitochondrial permeability transition pore formation by dimers of the F1FO ATP-synthase?
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- How much does https://doi.org/10.1038/onc.2014.462 net monthly?
- What is the earnings of https://link.springer.com/article/10.1038/onc.2014.96?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle?
- How much does http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20membrane%20permeabilization%20in%20cell%20death&journal=Physiol%20Rev&volume=87&pages=99-163&publication_year=2007&author=Kroemer%2CG&author=Galluzzi%2CL&author=Brenner%2CC net monthly?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Molecular%20definitions%20of%20cell%20death%20subroutines%3A%20recommendations%20of%20the%20Nomenclature%20Committee%20on%20Cell%20Death%202012&journal=Cell%20Death%20%26%20Differentiation&volume=19&issue=1&pages=107-120&publication_year=2011&author=Galluzzi%2CL&author=Vitale%2CI&author=Abrams%2CJ%20M&author=Alnemri%2CE%20S&author=Baehrecke%2CE%20H&author=Blagosklonny%2CM%20V&author=Dawson%2CT%20M&author=Dawson%2CV%20L&author=El-Deiry%2CW%20S&author=Fulda%2CS&author=Gottlieb%2CE&author=Green%2CD%20R&author=Hengartner%2CM%20O&author=Kepp%2CO&author=Knight%2CR%20A&author=Kumar%2CS&author=Lipton%2CS%20A&author=Lu%2CX&author=Madeo%2CF&author=Malorni%2CW&author=Mehlen%2CP&author=Nu%C3%B1ez%2CG&author=Peter%2CM%20E&author=Piacentini%2CM&author=Rubinsztein%2CD%20C&author=Shi%2CY&author=Simon%2CH-U&author=Vandenabeele%2CP&author=White%2CE&author=Yuan%2CJ&author=Zhivotovsky%2CB&author=Melino%2CG&author=Kroemer%2CG?
- How much money does http://scholar.google.com/scholar_lookup?&title=The%20permeability%20transition%20pore%20complex%20in%20cancer%20cell%20death&journal=Oncogene&volume=25&pages=4744-4756&publication_year=2006&author=Brenner%2CC&author=Grimm%2CS generate?
- Income figures for http://scholar.google.com/scholar_lookup?&title=The%20Ca2%2B-induced%20membrane%20transition%20in%20mitochondria.%20I.%20The%20protective%20mechanisms&journal=Arch%20Biochem%20Biophys&volume=195&pages=453-459&publication_year=1979&author=Hunter%2CDR&author=Haworth%2CRA
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Sequential%20reduction%20of%20mitochondrial%20transmembrane%20potential%20and%20generation%20of%20reactive%20oxygen%20species%20in%20early%20programmed%20cell%20death&journal=J%20Exp%20Med&volume=182&pages=367-377&publication_year=1995&author=Zamzami%2CN&author=Marchetti%2CP&author=Castedo%2CM&author=Decaudin%2CD&author=Macho%2CA&author=Hirsch%2CT?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Reduction%20in%20mitochondrial%20potential%20constitutes%20an%20early%20irreversible%20step%20of%20programmed%20lymphocyte%20death%20in%20vivo&journal=J%20Exp%20Med&volume=181&pages=1661-1672&publication_year=1995&author=Zamzami%2CN&author=Marchetti%2CP&author=Castedo%2CM&author=Zanin%2CC&author=Vayssiere%2CJL&author=Petit%2CPX earns monthly
- http://scholar.google.com/scholar_lookup?&title=Mitochondria%20and%20the%20autophagy-inflammation-cell%20death%20axis%20in%20organismal%20aging&journal=Science&volume=333&pages=1109-1112&publication_year=2011&author=Green%2CDR&author=Galluzzi%2CL&author=Kroemer%2CG's financial summary
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Molecular%20mechanisms%20of%20necroptosis%3A%20an%20ordered%20cellular%20explosion&journal=Nat%20Rev%20Mol%20Cell%20Biol&volume=11&pages=700-714&publication_year=2010&author=Vandenabeele%2CP&author=Galluzzi%2CL&author=Vanden%20Berghe%2CT&author=Kroemer%2CG?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=ATP%20synthesis%20and%20storage&journal=Purinergic%20Signal&volume=8&pages=343-357&publication_year=2012&author=Bonora%2CM&author=Patergnani%2CS&author=Rimessi%2CA&author=De%20Marchi%2CE&author=Suski%2CJM&author=Bononi%2CA have monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Mitochondria%3A%20master%20regulators%20of%20danger%20signalling&journal=Nat%20Rev%20Mol%20Cell%20Biol&volume=13&pages=780-788&publication_year=2012&author=Galluzzi%2CL&author=Kepp%2CO&author=Kroemer%2CG make?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Mitochondria%20and%20cell%20death%3A%20outer%20membrane%20permeabilization%20and%20beyond&journal=Nat%20Rev%20Mol%20Cell%20Biol&volume=11&pages=621-632&publication_year=2010&author=Tait%2CSW&author=Green%2CDR make?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Different%20mitochondrial%20intermembrane%20space%20proteins%20are%20released%20during%20apoptosis%20in%20a%20manner%20that%20is%20coordinately%20initiated%20but%20can%20vary%20in%20duration&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=103&pages=11573-11578&publication_year=2006&author=Munoz-Pinedo%2CC&author=Guio-Carrion%2CA&author=Goldstein%2CJC&author=Fitzgerald%2CP&author=Newmeyer%2CDD&author=Green%2CDR?
- http://scholar.google.com/scholar_lookup?&title=Classification%20of%20cell%20death%3A%20recommendations%20of%20the%20Nomenclature%20Committee%20on%20Cell%20Death%202009&journal=Cell%20Death%20%26%20Differentiation&volume=16&issue=1&pages=3-11&publication_year=2008&author=Kroemer%2CG&author=Galluzzi%2CL&author=Vandenabeele%2CP&author=Abrams%2CJ&author=Alnemri%2CE%20S&author=Baehrecke%2CE%20H&author=Blagosklonny%2CM%20V&author=El-Deiry%2CW%20S&author=Golstein%2CP&author=Green%2CD%20R&author=Hengartner%2CM&author=Knight%2CR%20A&author=Kumar%2CS&author=Lipton%2CS%20A&author=Malorni%2CW&author=Nu%C3%B1ez%2CG&author=Peter%2CM%20E&author=Tschopp%2CJ&author=Yuan%2CJ&author=Piacentini%2CM&author=Zhivotovsky%2CB&author=Melino%2CG income
- How much money does http://scholar.google.com/scholar_lookup?&title=Apoptosis%3A%20controlled%20demolition%20at%20the%20cellular%20level&journal=Nat%20Rev%20Mol%20Cell%20Biol&volume=9&pages=231-241&publication_year=2008&author=Taylor%2CRC&author=Cullen%2CSP&author=Martin%2CSJ generate?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Intracellular%20adenosine%20triphosphate%20%28ATP%29%20concentration%3A%20a%20switch%20in%20the%20decision%20between%20apoptosis%20and%20necrosis&journal=J%20Exp%20Med&volume=185&pages=1481-1486&publication_year=1997&author=Leist%2CM&author=Single%2CB&author=Castoldi%2CAF&author=Kuhnle%2CS&author=Nicotera%2CP
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=S-nitrosylation%20of%20mitochondrial%20caspases&journal=J%20Cell%20Biol&volume=154&pages=1111-1116&publication_year=2001&author=Mannick%2CJB&author=Schonhoff%2CC&author=Papeta%2CN&author=Ghafourifar%2CP&author=Szibor%2CM&author=Fang%2CK?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=XIAP%20discriminates%20between%20type%20I%20and%20type%20II%20FAS-induced%20apoptosis&journal=Nature&volume=460&pages=1035-1039&publication_year=2009&author=Jost%2CPJ&author=Grabow%2CS&author=Gray%2CD&author=McKenzie%2CMD&author=Nachbur%2CU&author=Huang%2CDC each month?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Catalytic%20activity%20of%20the%20caspase-8-FLIP%28L%29%20complex%20inhibits%20RIPK3-dependent%20necrosis&journal=Nature&volume=471&pages=363-367&publication_year=2011&author=Oberst%2CA&author=Dillon%2CCP&author=Weinlich%2CR&author=McCormick%2CLL&author=Fitzgerald%2CP&author=Pop%2CC?
- What's the profit of http://scholar.google.com/scholar_lookup?&title=The%20apoptosis-necrosis%20paradox.%20Apoptogenic%20proteases%20activated%20after%20mitochondrial%20permeability%20transition%20determine%20the%20mode%20of%20cell%20death&journal=Oncogene&volume=15&pages=1573-1581&publication_year=1997&author=Hirsch%2CT&author=Marchetti%2CP&author=Susin%2CSA&author=Dallaporta%2CB&author=Zamzami%2CN&author=Marzo%2CI?
- Profit of http://scholar.google.com/scholar_lookup?&title=Cyclophilin%20D%20is%20a%20component%20of%20mitochondrial%20permeability%20transition%20and%20mediates%20neuronal%20cell%20death%20after%20focal%20cerebral%20ischemia&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=102&pages=12005-12010&publication_year=2005&author=Schinzel%2CAC&author=Takeuchi%2CO&author=Huang%2CZ&author=Fisher%2CJK&author=Zhou%2CZ&author=Rubens%2CJ
- How much does http://scholar.google.com/scholar_lookup?&title=Loss%20of%20cyclophilin%20D%20reveals%20a%20critical%20role%20for%20mitochondrial%20permeability%20transition%20in%20cell%20death&journal=Nature&volume=434&pages=658-662&publication_year=2005&author=Baines%2CCP&author=Kaiser%2CRA&author=Purcell%2CNH&author=Blair%2CNS&author=Osinska%2CH&author=Hambleton%2CMA gross monthly?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Cyclophilin%20D-dependent%20mitochondrial%20permeability%20transition%20regulates%20some%20necrotic%20but%20not%20apoptotic%20cell%20death&journal=Nature&volume=434&pages=652-658&publication_year=2005&author=Nakagawa%2CT&author=Shimizu%2CS&author=Watanabe%2CT&author=Yamaguchi%2CO&author=Otsu%2CK&author=Yamagata%2CH generate?
- http://scholar.google.com/scholar_lookup?&title=Bax%20regulates%20primary%20necrosis%20through%20mitochondrial%20dynamics&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=109&pages=6566-6571&publication_year=2012&author=Whelan%2CRS&author=Konstantinidis%2CK&author=Wei%2CAC&author=Chen%2CY&author=Reyna%2CDE&author=Jha%2CS's financial summary
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Two%20independent%20pathways%20of%20regulated%20necrosis%20mediate%20ischemia-reperfusion%20injury&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=110&pages=12024-12029&publication_year=2013&author=Linkermann%2CA&author=Brasen%2CJH&author=Darding%2CM&author=Jin%2CMK&author=Sanz%2CAB&author=Heller%2CJO?
- How much does http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20permeability%20transition%20pore%20component%20cyclophilin%20D%20distinguishes%20nigrostriatal%20dopaminergic%20death%20paradigms%20in%20the%20MPTP%20mouse%20model%20of%20Parkinson%27s%20disease&journal=Antioxid%20Redox%20Signal&volume=16&pages=855-868&publication_year=2012&author=Thomas%2CB&author=Banerjee%2CR&author=Starkova%2CNN&author=Zhang%2CSF&author=Calingasan%2CNY&author=Yang%2CL make?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Cyclophilin%20D%20deficiency%20protects%20against%20acetaminophen-induced%20oxidant%20stress%20and%20liver%20injury&journal=Free%20Radic%20Res&volume=45&pages=156-164&publication_year=2011&author=Ramachandran%2CA&author=Lebofsky%2CM&author=Baines%2CCP&author=Lemasters%2CJJ&author=Jaeschke%2CH
- How much does http://scholar.google.com/scholar_lookup?&title=Pharmacologic%20targeting%20or%20genetic%20deletion%20of%20mitochondrial%20cyclophilin%20D%20protects%20from%20NSAID-induced%20small%20intestinal%20ulceration%20in%20mice&journal=Toxicol%20Sci&volume=118&pages=276-285&publication_year=2010&author=LoGuidice%2CA&author=Ramirez-Alcantara%2CV&author=Proli%2CA&author=Gavillet%2CB&author=Boelsterli%2CUA bring in each month?
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20permeability%20transition%20as%20a%20novel%20principle%20of%20hepatorenal%20toxicity%20in%20vivo&journal=Apoptosis&volume=7&pages=395-405&publication_year=2002&author=Haouzi%2CD&author=Cohen%2CI&author=Vieira%2CHL&author=Poncet%2CD&author=Boya%2CP&author=Castedo%2CM
- What's http://scholar.google.com/scholar_lookup?&title=Targeting%20cyclophilin%20D%20and%20the%20mitochondrial%20permeability%20transition%20enhances%20beta-cell%20survival%20and%20prevents%20diabetes%20in%20Pdx1%20deficiency&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=107&pages=10214-10219&publication_year=2010&author=Fujimoto%2CK&author=Chen%2CY&author=Polonsky%2CKS&author=Dorn%2CGW's gross income?
- Revenue of http://scholar.google.com/scholar_lookup?&title=Genetic%20ablation%20of%20cyclophilin%20D%20rescues%20mitochondrial%20defects%20and%20prevents%20muscle%20apoptosis%20in%20collagen%20VI%20myopathic%20mice&journal=Hum%20Mol%20Genet&volume=18&pages=2024-2031&publication_year=2009&author=Palma%2CE&author=Tiepolo%2CT&author=Angelin%2CA&author=Sabatelli%2CP&author=Maraldi%2CNM&author=Basso%2CE
- How much does http://scholar.google.com/scholar_lookup?&title=Genetic%20and%20pharmacologic%20inhibition%20of%20mitochondrial-dependent%20necrosis%20attenuates%20muscular%20dystrophy&journal=Nat%20Med&volume=14&pages=442-447&publication_year=2008&author=Millay%2CDP&author=Sargent%2CMA&author=Osinska%2CH&author=Baines%2CCP&author=Barton%2CER&author=Vuagniaux%2CG gross monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Molecular%20mechanisms%20of%20cisplatin%20resistance&journal=Oncogene&volume=31&pages=1869-1883&publication_year=2012&author=Galluzzi%2CL&author=Senovilla%2CL&author=Vitale%2CI&author=Michels%2CJ&author=Martins%2CI&author=Kepp%2CO net monthly?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Mechanism%20of%20apoptosis%20induction%20by%20inhibition%20of%20the%20anti-apoptotic%20BCL-2%20proteins&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=105&pages=20327-20332&publication_year=2008&author=Chipuk%2CJE&author=Fisher%2CJC&author=Dillon%2CCP&author=Kriwacki%2CRW&author=Kuwana%2CT&author=Green%2CDR
- http://scholar.google.com/scholar_lookup?&title=Targeting%20Bax%20interaction%20sites%20reveals%20that%20only%20homo-oligomerization%20sites%20are%20essential%20for%20its%20activation&journal=Cell%20Death%20Differ&volume=20&pages=744-754&publication_year=2013&author=Peng%2CR&author=Tong%2CJS&author=Li%2CH&author=Yue%2CB&author=Zou%2CF&author=Yu%2CJ's total income per month
- Revenue of http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20membrane%20permeabilization%20in%20neuronal%20injury&journal=Nat%20Rev%20Neurosci&volume=10&pages=481-494&publication_year=2009&author=Galluzzi%2CL&author=Blomgren%2CK&author=Kroemer%2CG
- See how much http://scholar.google.com/scholar_lookup?&title=Targeting%20mitochondria%20for%20cancer%20therapy&journal=Nat%20Rev%20Drug%20Discov&volume=9&pages=447-464&publication_year=2010&author=Fulda%2CS&author=Galluzzi%2CL&author=Kroemer%2CG makes per month
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Mitochondria%20as%20therapeutic%20targets%20for%20cancer%20chemotherapy&journal=Oncogene&volume=25&pages=4812-4830&publication_year=2006&author=Galluzzi%2CL&author=Larochette%2CN&author=Zamzami%2CN&author=Kroemer%2CG bring in?
- How much money does http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20the%20mitochondrial%20permeability%20transition%20for%20cytoprotection%3A%20direct%20versus%20indirect%20Mechanisms&journal=Biochem%20Res%20Int&volume=2012&publication_year=2012&author=Martel%2CC&author=Huynh%20le%2CH&author=Garnier%2CA&author=Ventura-Clapier%2CR&author=Brenner%2CC make?
- How much does http://scholar.google.com/scholar_lookup?&title=Cell%20death%20assays%20for%20drug%20discovery&journal=Nat%20Rev%20Drug%20Discov&volume=10&pages=221-237&publication_year=2011&author=Kepp%2CO&author=Galluzzi%2CL&author=Lipinski%2CM&author=Yuan%2CJ&author=Kroemer%2CG earn?
- How much does http://scholar.google.com/scholar_lookup?&title=Individuality%3A%20the%20barrier%20to%20optimal%20immunosuppression&journal=Nat%20Rev%20Immunol&volume=3&pages=831-838&publication_year=2003&author=Kahan%2CBD generate monthly?
- http://scholar.google.com/scholar_lookup?&title=The%20apoptotic%20pore%20on%20mitochondria%3A%20are%20we%20breaking%20through%20or%20still%20stuck%3F&journal=Cell%20Death%20Differ&volume=21&pages=187-191&publication_year=2014&author=Borner%2CC&author=Andrews%2CDW's revenue stream
- How much does http://scholar.google.com/scholar_lookup?&title=The%20mitochondrial%20megachannel%20is%20the%20permeability%20transition%20pore&journal=J%20Bioenerg%20Biomembr&volume=24&pages=111-117&publication_year=1992&author=Szabo%2CI&author=Zoratti%2CM pull in monthly?
- How much profit is http://scholar.google.com/scholar_lookup?&title=Modulation%20of%20the%20mitochondrial%20megachannel%20by%20divalent%20cations%20and%20protons&journal=J%20Biol%20Chem&volume=267&pages=2940-2946&publication_year=1992&author=Szabo%2CI&author=Bernardi%2CP&author=Zoratti%2CM making per month?
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=The%20mitochondrial%20permeability%20transition%20pore%20may%20comprise%20VDAC%20molecules.%20I.%20Binary%20structure%20and%20voltage%20dependence%20of%20the%20pore&journal=FEBS%20Lett&volume=330&pages=201-205&publication_year=1993&author=Szabo%2CI&author=Zoratti%2CM?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20mitochondrial%20permeability%20transition%20pore%20may%20comprise%20VDAC%20molecules.%20II.%20The%20electrophysiological%20properties%20of%20VDAC%20are%20compatible%20with%20those%20of%20the%20mitochondrial%20megachannel&journal=FEBS%20Lett&volume=330&pages=206-210&publication_year=1993&author=Szabo%2CI&author=De%20Pinto%2CV&author=Zoratti%2CM gross monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Isolation%20of%20the%20mitochondrial%20benzodiazepine%20receptor%3A%20association%20with%20the%20voltage-dependent%20anion%20channel%20and%20the%20adenine%20nucleotide%20carrier&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=89&pages=3170-3174&publication_year=1992&author=McEnery%2CMW&author=Snowman%2CAM&author=Trifiletti%2CRR&author=Snyder%2CSH make?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Complexes%20between%20kinases%2C%20mitochondrial%20porin%20and%20adenylate%20translocator%20in%20rat%20brain%20resemble%20the%20permeability%20transition%20pore&journal=FEBS%20Lett&volume=396&pages=189-195&publication_year=1996&author=Beutner%2CG&author=Ruck%2CA&author=Riede%2CB&author=Welte%2CW&author=Brdiczka%2CD
- Income figures for http://scholar.google.com/scholar_lookup?&title=Complexes%20between%20porin%2C%20hexokinase%2C%20mitochondrial%20creatine%20kinase%20and%20adenylate%20translocator%20display%20properties%20of%20the%20permeability%20transition%20pore.%20Implication%20for%20regulation%20of%20permeability%20transition%20by%20the%20kinases&journal=Biochim%20Biophys%20Acta&volume=1368&pages=7-18&publication_year=1998&author=Beutner%2CG&author=Ruck%2CA&author=Riede%2CB&author=Brdiczka%2CD
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Cyclophilin-D%20binds%20strongly%20to%20complexes%20of%20the%20voltage-dependent%20anion%20channel%20and%20the%20adenine%20nucleotide%20translocase%20to%20form%20the%20permeability%20transition%20pore&journal=Eur%20J%20Biochem&volume=258&pages=729-735&publication_year=1998&author=Crompton%2CM&author=Virji%2CS&author=Ward%2CJM?
- http://scholar.google.com/scholar_lookup?&title=Involvement%20of%20cyclophilin%20D%20in%20the%20activation%20of%20a%20mitochondrial%20pore%20by%20Ca2%2B%20and%20oxidant%20stress&journal=Eur%20J%20Biochem&volume=238&pages=166-172&publication_year=1996&author=Tanveer%2CA&author=Virji%2CS&author=Andreeva%2CL&author=Totty%2CNF&author=Hsuan%2CJJ&author=Ward%2CJM income
- See how much http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20Ca2%28%2B%29-induced%20large-amplitude%20swelling%20of%20liver%20and%20heart%20mitochondria%20by%20cyclosporin%20is%20probably%20caused%20by%20the%20inhibitor%20binding%20to%20mitochondrial-matrix%20peptidyl-prolyl%20cis-trans%20isomerase%20and%20preventing%20it%20interacting%20with%20the%20adenine%20nucleotide%20translocase&journal=Biochem%20J&volume=268&pages=153-160&publication_year=1990&author=Halestrap%2CAP&author=Davidson%2CAM makes per month
- How much profit does http://scholar.google.com/scholar_lookup?&title=Reconstituted%20adenine%20nucleotide%20translocase%20forms%20a%20channel%20for%20small%20molecules%20comparable%20to%20the%20mitochondrial%20permeability%20transition%20pore&journal=FEBS%20Lett&volume=426&pages=97-101&publication_year=1998&author=Ruck%2CA&author=Dolder%2CM&author=Wallimann%2CT&author=Brdiczka%2CD generate?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20ADP%2FATP%20translocator%20is%20not%20essential%20for%20the%20mitochondrial%20permeability%20transition%20pore&journal=Nature&volume=427&pages=461-465&publication_year=2004&author=Kokoszka%2CJE&author=Waymire%2CKG&author=Levy%2CSE&author=Sligh%2CJE&author=Cai%2CJ&author=Jones%2CDP produce monthly?
- How much does http://scholar.google.com/scholar_lookup?&title=Voltage-dependent%20anion%20channels%20are%20dispensable%20for%20mitochondrial-dependent%20cell%20death&journal=Nat%20Cell%20Biol&volume=9&pages=550-555&publication_year=2007&author=Baines%2CCP&author=Kaiser%2CRA&author=Sheiko%2CT&author=Craigen%2CWJ&author=Molkentin%2CJD bring in each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20apoptosis%20without%20VDAC&journal=Nat%20Cell%20Biol&volume=9&pages=487-489&publication_year=2007&author=Galluzzi%2CL&author=Kroemer%2CG pull in?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Properties%20of%20the%20permeability%20transition%20pore%20in%20mitochondria%20devoid%20of%20Cyclophilin%20D&journal=J%20Biol%20Chem&volume=280&pages=18558-18561&publication_year=2005&author=Basso%2CE&author=Fante%2CL&author=Fowlkes%2CJ&author=Petronilli%2CV&author=Forte%2CMA&author=Bernardi%2CP
- How much money does http://scholar.google.com/scholar_lookup?&title=A%20fourth%20ADP%2FATP%20carrier%20isoform%20in%20man%3A%20identification%2C%20bacterial%20expression%2C%20functional%20characterization%20and%20tissue%20distribution&journal=FEBS%20Lett&volume=579&pages=633-637&publication_year=2005&author=Dolce%2CV&author=Scarcia%2CP&author=Iacopetta%2CD&author=Palmieri%2CF make?
- http://scholar.google.com/scholar_lookup?&title=Adenine%20nucleotide%20translocase%203%20%28ANT3%29%20overexpression%20induces%20apoptosis%20in%20cultured%20cells&journal=FEBS%20Lett&volume=563&pages=155-160&publication_year=2004&author=Zamora%2CM&author=Granell%2CM&author=Mampel%2CT&author=Vinas%2CO's revenue stream
- How much does http://scholar.google.com/scholar_lookup?&title=VDAC2%20inhibits%20BAK%20activation%20and%20mitochondrial%20apoptosis&journal=Science&volume=301&pages=513-517&publication_year=2003&author=Cheng%2CEH&author=Sheiko%2CTV&author=Fisher%2CJK&author=Craigen%2CWJ&author=Korsmeyer%2CSJ make?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Bid-induced%20conformational%20change%20of%20Bax%20is%20responsible%20for%20mitochondrial%20cytochrome%20c%20release%20during%20apoptosis&journal=J%20Cell%20Biol&volume=144&pages=891-901&publication_year=1999&author=Desagher%2CS&author=Osen-Sand%2CA&author=Nichols%2CA&author=Eskes%2CR&author=Montessuit%2CS&author=Lauper%2CS
- http://scholar.google.com/scholar_lookup?&title=Osmotic%20reversal%20of%20phosphate-induced%20mitochondrial%20swelling&journal=Biochim%20Biophys%20Acta&volume=104&pages=612-615&publication_year=1965&author=Tedeschi%2CH&author=Hegarty%2CHJ&author=James%2CJM's revenue stream
- How much revenue does http://scholar.google.com/scholar_lookup?&title=The%20mitochondrial%20transporter%20family%20%28SLC25%29%3A%20physiological%20and%20pathological%20implications&journal=Pflugers%20Arch&volume=447&pages=689-709&publication_year=2004&author=Palmieri%2CF bring in?
- How much money does http://scholar.google.com/scholar_lookup?&title=Permeability%20transition%20in%20rat%20liver%20mitochondria%20is%20modulated%20by%20the%20ATP-Mg%2FPi%20carrier&journal=Am%20J%20Physiol%20Gastrointest%20Liver%20Physiol&volume=285&pages=G274-G281&publication_year=2003&author=Hagen%2CT&author=Lagace%2CCJ&author=Modica-Napolitano%2CJS&author=Aprille%2CJR make?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=SCaMC-1%20promotes%20cancer%20cell%20survival%20by%20desensitizing%20mitochondrial%20permeability%20transition%20via%20ATP%2FADP-mediated%20matrix%20Ca%282%2B%29%20buffering&journal=Cell%20Death%20Differ&volume=19&pages=650-660&publication_year=2012&author=Traba%2CJ&author=Del%20Arco%2CA&author=Duchen%2CMR&author=Szabadkai%2CG&author=Satrustegui%2CJ?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Cytopathic%20effects%20of%20the%20cytomegalovirus-encoded%20apoptosis%20inhibitory%20protein%20vMIA&journal=J%20Cell%20Biol&volume=174&pages=985-996&publication_year=2006&author=Poncet%2CD&author=Pauleau%2CAL&author=Szabadkai%2CG&author=Vozza%2CA&author=Scholz%2CSR&author=Le%20Bras%2CM?
- Find out how much http://scholar.google.com/scholar_lookup?&title=Viral%20control%20of%20mitochondrial%20apoptosis&journal=PLoS%20Pathog&volume=4&publication_year=2008&author=Galluzzi%2CL&author=Brenner%2CC&author=Morselli%2CE&author=Touat%2CZ&author=Kroemer%2CG earns monthly
- How much profit does http://scholar.google.com/scholar_lookup?&title=The%20mitochondrial%20phosphate%20carrier%20interacts%20with%20cyclophilin%20D%20and%20may%20play%20a%20key%20role%20in%20the%20permeability%20transition&journal=J%20Biol%20Chem&volume=283&pages=26312-26323&publication_year=2008&author=Leung%2CAW&author=Varanyuwatana%2CP&author=Halestrap%2CAP generate?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=A%20high-throughput%20screening%20for%20mammalian%20cell%20death%20effectors%20identifies%20the%20mitochondrial%20phosphate%20carrier%20as%20a%20regulator%20of%20cytochrome%20c%20release&journal=Oncogene&volume=27&pages=44-54&publication_year=2008&author=Alcala%2CS&author=Klee%2CM&author=Fernandez%2CJ&author=Fleischer%2CA&author=Pimentel-Muinos%2CFX?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=The%20reversible%20antiport-uniport%20conversion%20of%20the%20phosphate%20carrier%20from%20yeast%20mitochondria%20depends%20on%20the%20presence%20of%20a%20single%20cysteine&journal=J%20Biol%20Chem&volume=272&pages=10558-10564&publication_year=1997&author=Schroers%2CA&author=Kramer%2CR&author=Wohlrab%2CH have monthly?
- http://scholar.google.com/scholar_lookup?&title=The%20roles%20of%20phosphate%20and%20the%20phosphate%20carrier%20in%20the%20mitochondrial%20permeability%20transition%20pore&journal=Mitochondrion&volume=12&pages=120-125&publication_year=2012&author=Varanyuwatana%2CP&author=Halestrap%2CAP's financial summary
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Unexpected%20role%20of%20the%20phosphate%20carrier%20in%20mitochondrial%20fragmentation&journal=Cell%20Death%20Differ&volume=15&pages=616-618&publication_year=2008&author=Pauleau%2CAL&author=Galluzzi%2CL&author=Scholz%2CSR&author=Larochette%2CN&author=Kepp%2CO&author=Kroemer%2CG
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Dynamic%20evolution%20of%20the%20adenine%20nucleotide%20translocase%20interactome%20during%20chemotherapy-induced%20apoptosis&journal=Oncogene&volume=23&pages=8049-8064&publication_year=2004&author=Verrier%2CF&author=Deniaud%2CA&author=Lebras%2CM&author=Metivier%2CD&author=Kroemer%2CG&author=Mignotte%2CB is on a monthly basis
- http://scholar.google.com/scholar_lookup?&title=Mitochondrial%20benzodiazepine%20receptors%20regulate%20steroid%20biosynthesis&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=86&pages=9813-9816&publication_year=1989&author=Mukhin%2CAG&author=Papadopoulos%2CV&author=Costa%2CE&author=Krueger%2CKE's financial summary
- How much profit does http://scholar.google.com/scholar_lookup?&title=Protoporphyrin%20IX%2C%20an%20endogenous%20ligand%20of%20the%20peripheral%20benzodiazepine%20receptor%2C%20potentiates%20induction%20of%20the%20mitochondrial%20permeability%20transition%20and%20the%20killing%20of%20cultured%20hepatocytes%20by%20rotenone&journal=J%20Biol%20Chem&volume=269&pages=31041-31046&publication_year=1994&author=Pastorino%2CJG&author=Simbula%2CG&author=Gilfor%2CE&author=Hoek%2CJB&author=Farber%2CJL make?
- http://scholar.google.com/scholar_lookup?&title=PK11195%2C%20a%20ligand%20of%20the%20mitochondrial%20benzodiazepine%20receptor%2C%20facilitates%20the%20induction%20of%20apoptosis%20and%20reverses%20Bcl-2-mediated%20cytoprotection&journal=Exp%20Cell%20Res&volume=241&pages=426-434&publication_year=1998&author=Hirsch%2CT&author=Decaudin%2CD&author=Susin%2CSA&author=Marchetti%2CP&author=Larochette%2CN&author=Resche-Rigon%2CM's financial summary
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Peripheral-type%20benzodiazepine%20receptor%20ligands%3A%20mitochondrial%20permeability%20transition%20induction%20in%20rat%20cardiac%20tissue&journal=Biochem%20Pharmacol&volume=61&pages=695-705&publication_year=2001&author=Chelli%2CB&author=Falleni%2CA&author=Salvetti%2CF&author=Gremigni%2CV&author=Lucacchini%2CA&author=Martini%2CC?
- How much does http://scholar.google.com/scholar_lookup?&title=The%20peripheral-type%20benzodiazepine%20receptor%20is%20involved%20in%20control%20of%20Ca2%2B-induced%20permeability%20transition%20pore%20opening%20in%20rat%20brain%20mitochondria&journal=Cell%20Calcium&volume=42&pages=27-39&publication_year=2007&author=Azarashvili%2CT&author=Grachev%2CD&author=Krestinina%2CO&author=Evtodienko%2CY&author=Yurkov%2CI&author=Papadopoulos%2CV net monthly?
- http://scholar.google.com/scholar_lookup?&title=PK11195%2C%20a%20specific%20ligand%20of%20the%20peripheral%20benzodiazepine%20receptor%2C%20may%20protect%20pancreatic%20beta-cells%20from%20cytokine-induced%20cell%20death&journal=Artif%20Cells%20Blood%20Substit%20Immobil%20Biotechnol&volume=40&pages=56-61&publication_year=2012&author=Klaffschenkel%2CRA&author=Waidmann%2CM&author=Northoff%2CH&author=Mahmoud%2CAA&author=Lembert%2CN's financial summary
- http://scholar.google.com/scholar_lookup?&title=Ligands%20of%20the%20mitochondrial%2018%E2%80%89kDa%20translocator%20protein%20attenuate%20apoptosis%20of%20human%20glioblastoma%20cells%20exposed%20to%20erucylphosphohomocholine&journal=Cell%20Oncol&volume=30&pages=435-450&publication_year=2008&author=Kugler%2CW&author=Veenman%2CL&author=Shandalov%2CY&author=Leschiner%2CS&author=Spanier%2CI&author=Lakomek%2CM's revenue stream
- What are the earnings of http://scholar.google.com/scholar_lookup?&title=The%20nitric%20oxide%20donor%20sodium%20nitroprusside%20requires%20the%2018%E2%80%89kDa%20Translocator%20Protein%20to%20induce%20cell%20death&journal=Apoptosis&volume=17&pages=647-665&publication_year=2012&author=Shargorodsky%2CL&author=Veenman%2CL&author=Caballero%2CB&author=Pe%27er%2CY&author=Leschiner%2CS&author=Bode%2CJ?
- How much does http://scholar.google.com/scholar_lookup?&title=Modulation%20of%20intracellular%20Ca2%2B%20signalling%20in%20HeLa%20cells%20by%20the%20apoptotic%20cell%20death%20enhancer%20PK11195&journal=Biochem%20Pharmacol&volume=76&pages=1628-1636&publication_year=2008&author=Campanella%2CM&author=Szabadkai%2CG&author=Rizzuto%2CR generate monthly?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Peripheral%20benzodiazepine%20receptor%20ligands%20reverse%20apoptosis%20resistance%20of%20cancer%20cells%20in%20vitro%20and%20in%20vivo&journal=Cancer%20Res&volume=62&pages=1388-1393&publication_year=2002&author=Decaudin%2CD&author=Castedo%2CM&author=Nemati%2CF&author=Beurdeley-Thomas%2CA&author=De%20Pinieux%2CG&author=Caron%2CA
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=PK11195%20potently%20sensitizes%20to%20apoptosis%20induction%20independently%20from%20the%20peripheral%20benzodiazepin%20receptor&journal=Oncogene&volume=24&pages=7503-7513&publication_year=2005&author=Gonzalez-Polo%2CRA&author=Carvalho%2CG&author=Braun%2CT&author=Decaudin%2CD&author=Fabre%2CC&author=Larochette%2CN?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Some%20new%20aspects%20of%20creatine%20kinase%20%28CK%29%3A%20compartmentation%2C%20structure%2C%20function%20and%20regulation%20for%20cellular%20and%20mitochondrial%20bioenergetics%20and%20physiology&journal=Biofactors&volume=8&pages=229-234&publication_year=1998&author=Wallimann%2CT&author=Dolder%2CM&author=Schlattner%2CU&author=Eder%2CM&author=Hornemann%2CT&author=O%27Gorman%2CE?
- Profit of http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20the%20mitochondrial%20permeability%20transition%20by%20creatine%20kinase%20substrates.%20Requirement%20for%20microcompartmentation&journal=J%20Biol%20Chem&volume=278&pages=17760-17766&publication_year=2003&author=Dolder%2CM&author=Walzel%2CB&author=Speer%2CO&author=Schlattner%2CU&author=Wallimann%2CT
- Profit of http://scholar.google.com/scholar_lookup?&title=Isozymes%20of%20mammalian%20hexokinase%3A%20structure%2C%20subcellular%20localization%20and%20metabolic%20function&journal=J%20Exp%20Biol&volume=206&pages=2049-2057&publication_year=2003&author=Wilson%2CJE
- How much income does http://scholar.google.com/scholar_lookup?&title=Regulation%20of%20hexokinase%20binding%20to%20VDAC&journal=J%20Bioenerg%20Biomembr&volume=40&pages=171-182&publication_year=2008&author=Pastorino%2CJG&author=Hoek%2CJB have?
- Revenue of http://scholar.google.com/scholar_lookup?&title=Hexokinase%20II%3A%20the%20integration%20of%20energy%20metabolism%20and%20control%20of%20apoptosis&journal=Curr%20Med%20Chem&volume=10&pages=1535-1551&publication_year=2003&author=Pastorino%2CJG&author=Hoek%2CJB
- What's the income of http://scholar.google.com/scholar_lookup?&title=Disruption%20of%20the%20hexokinase-VDAC%20complex%20for%20tumor%20therapy&journal=Oncogene&volume=27&pages=4633-4635&publication_year=2008&author=Galluzzi%2CL&author=Kepp%2CO&author=Tajeddine%2CN&author=Kroemer%2CG?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Methyl%20jasmonate%20binds%20to%20and%20detaches%20mitochondria-bound%20hexokinase&journal=Oncogene&volume=27&pages=4636-4643&publication_year=2008&author=Goldin%2CN&author=Arzoine%2CL&author=Heyfets%2CA&author=Israelson%2CA&author=Zaslavsky%2CZ&author=Bravman%2CT each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Voltage-dependent%20anion%20channel%201-based%20peptides%20interact%20with%20hexokinase%20to%20prevent%20its%20anti-apoptotic%20activity&journal=J%20Biol%20Chem&volume=284&pages=3946-3955&publication_year=2009&author=Arzoine%2CL&author=Zilberberg%2CN&author=Ben-Romano%2CR&author=Shoshan-Barmatz%2CV bring in each month?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Disruption%20of%20hexokinase%20II-mitochondrial%20binding%20blocks%20ischemic%20preconditioning%20and%20causes%20rapid%20cardiac%20necrosis&journal=Circ%20Res&volume=108&pages=1165-1169&publication_year=2011&author=Smeele%2CKM&author=Southworth%2CR&author=Wu%2CR&author=Xie%2CC&author=Nederlof%2CR&author=Warley%2CA?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Metabolic%20targets%20for%20cancer%20therapy&journal=Nat%20Rev%20Drug%20Discov&volume=12&pages=829-846&publication_year=2013&author=Galluzzi%2CL&author=Kepp%2CO&author=Vander%20Heiden%2CMG&author=Kroemer%2CG generate?
- http://scholar.google.com/scholar_lookup?&title=Glucose%20phosphorylation%20and%20mitochondrial%20binding%20are%20required%20for%20the%20protective%20effects%20of%20hexokinases%20I%20and%20II&journal=Mol%20Cell%20Biol&volume=28&pages=1007-1017&publication_year=2008&author=Sun%2CL&author=Shukair%2CS&author=Naik%2CTJ&author=Moazed%2CF&author=Ardehali%2CH income
- http://scholar.google.com/scholar_lookup?&title=Hexokinase%20II%20detachment%20from%20mitochondria%20triggers%20apoptosis%20through%20the%20permeability%20transition%20pore%20independent%20of%20voltage-dependent%20anion%20channels&journal=PLoS%20ONE&volume=3&publication_year=2008&author=Chiara%2CF&author=Castellaro%2CD&author=Marin%2CO&author=Petronilli%2CV&author=Brusilow%2CWS&author=Juhaszova%2CM's financial summary
- How much does http://scholar.google.com/scholar_lookup?&title=Hexokinase%201%20blocks%20apoptotic%20signals%20at%20the%20mitochondria&journal=Cell%20Signal&volume=25&pages=2685-2692&publication_year=2013&author=Schindler%2CA&author=Foley%2CE pull in?
- How much does http://scholar.google.com/scholar_lookup?&title=Activation%20of%20glycogen%20synthase%20kinase%203beta%20disrupts%20the%20binding%20of%20hexokinase%20II%20to%20mitochondria%20by%20phosphorylating%20voltage-dependent%20anion%20channel%20and%20potentiates%20chemotherapy-induced%20cytotoxicity&journal=Cancer%20Res&volume=65&pages=10545-10554&publication_year=2005&author=Pastorino%2CJG&author=Hoek%2CJB&author=Shulga%2CN net monthly?
- See how much http://scholar.google.com/scholar_lookup?&title=Protein%20kinase%20Cepsilon%20interacts%20with%20and%20inhibits%20the%20permeability%20transition%20pore%20in%20cardiac%20mitochondria&journal=Circ%20Res&volume=92&pages=873-880&publication_year=2003&author=Baines%2CCP&author=Song%2CCX&author=Zheng%2CYT&author=Wang%2CGW&author=Zhang%2CJ&author=Wang%2COL makes per month
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=Anti-apoptotic%20effect%20of%20cGMP%20in%20cultured%20astrocytes%3A%20inhibition%20by%20cGMP-dependent%20protein%20kinase%20of%20mitochondrial%20permeable%20transition%20pore&journal=J%20Biol%20Chem&volume=276&pages=48093-48099&publication_year=2001&author=Takuma%2CK&author=Phuagphong%2CP&author=Lee%2CE&author=Mori%2CK&author=Baba%2CA&author=Matsuda%2CT?
- How much does http://scholar.google.com/scholar_lookup?&title=Glycogen%20synthase%20kinase%203%20inhibition%20slows%20mitochondrial%20adenine%20nucleotide%20transport%20and%20regulates%20voltage-dependent%20anion%20channel%20phosphorylation&journal=Circ%20Res&volume=103&pages=983-991&publication_year=2008&author=Das%2CS&author=Wong%2CR&author=Rajapakse%2CN&author=Murphy%2CE&author=Steenbergen%2CC rake in every month?
- How much money does http://scholar.google.com/scholar_lookup?&title=Modulation%20of%20the%20mitochondrial%20permeability%20transition%20pore%20complex%20in%20GSK-3beta-mediated%20myocardial%20protection&journal=J%20Mol%20Cell%20Cardiol&volume=43&pages=564-570&publication_year=2007&author=Nishihara%2CM&author=Miura%2CT&author=Miki%2CT&author=Tanno%2CM&author=Yano%2CT&author=Naitoh%2CK make?
- How much does http://scholar.google.com/scholar_lookup?&title=Chemotherapeutic%20induction%20of%20mitochondrial%20oxidative%20stress%20activates%20GSK-3alpha%2Fbeta%20and%20Bax%2C%20leading%20to%20permeability%20transition%20pore%20opening%20and%20tumor%20cell%20death&journal=Cell%20Death%20Dis&volume=3&publication_year=2012&author=Chiara%2CF&author=Gambalunga%2CA&author=Sciacovelli%2CM&author=Nicolli%2CA&author=Ronconi%2CL&author=Fregona%2CD net monthly?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=Activation%20of%20mitochondrial%20ERK%20protects%20cancer%20cells%20from%20death%20through%20inhibition%20of%20the%20permeability%20transition&journal=Proc%20Natl%20Acad%20Sci%20USA&volume=107&pages=726-731&publication_year=2010&author=Rasola%2CA&author=Sciacovelli%2CM&author=Chiara%2CF&author=Pantic%2CB&author=Brusilow%2CWS&author=Bernardi%2CP?
- http://scholar.google.com/scholar_lookup?&title=Local%20delivery%20of%20PKCepsilon-activating%20peptide%20mimics%20ischemic%20preconditioning%20in%20aged%20hearts%20through%20GSK-3beta%20but%20not%20F1-ATPase%20inactivation&journal=Am%20J%20Physiol%20Heart%20Circ%20Physiol&volume=293&pages=H2056-H2063&publication_year=2007&author=Korzick%2CDH&author=Kostyak%2CJC&author=Hunter%2CJC&author=Saupe%2CKW's revenue stream
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=Glycogen%20synthase%20kinase-3beta%20mediates%20convergence%20of%20protection%20signaling%20to%20inhibit%20the%20mitochondrial%20permeability%20transition%20pore&journal=J%20Clin%20Invest&volume=113&pages=1535-1549&publication_year=2004&author=Juhaszova%2CM&author=Zorov%2CDB&author=Kim%2CSH&author=Pepe%2CS&author=Fu%2CQ&author=Fishbein%2CKW?
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- What's the profit of http://scholar.google.com/scholar_lookup?&title=IF%281%29%3A%20setting%20the%20pace%20of%20the%20F%281%29F%28o%29-ATP%20synthase&journal=Trends%20Biochem%20Sci&volume=34&pages=343-350&publication_year=2009&author=Campanella%2CM&author=Parker%2CN&author=Tan%2CCH&author=Hall%2CAM&author=Duchen%2CMR?
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