
NATURE . COM {
}
Title:
ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma | Oncogene
Description:
Successful treatment of diffuse large B-cell lymphoma (DLBCL) is frequently hindered by the development of resistance to conventional chemotherapy resulting in disease relapse and high mortality. High expression of antiapoptotic and/or drug transporter proteins induced by oncogenic signaling pathways has been implicated in the development of chemoresistance in cancer. Previously, our studies showed that high expression of adenosine triphosphate-binding cassette drug transporter ABCG2 in DLBCL correlated inversely with disease- and failure-free survival. In this study, we have implicated activated hedgehog (Hh) signaling pathway as a key factor behind high ABCG2 expression in DLBCL through direct upregulation of ABCG2 gene transcription. We have identified a single binding site for GLI transcription factors in the ABCG2 promoter and established its functionality using luciferase reporter, site-directed mutagenesis and chromatin-immunoprecipitation assays. Furthermore, in DLBCL tumor samples, significantly high ABCG2 and GLI1 levels were found in DLBCL tumors with lymph node involvement in comparison with DLBCL tumor cells collected from pleural and/or peritoneal effusions. This suggests a role for the stromal microenvironment in maintaining high levels of ABCG2 and GLI1. Accordingly, in vitro co-culture of DLBCL cells with HS-5 stromal cells increased ABCG2 mRNA and protein levels by paracrine activation of Hh signaling. In addition to ABCG2, co-culture of DLBCL cells with HS-5 cells also resulted in increase expression of the antiapoptotic proteins BCL2, BCL-xL and BCL2A1 and in induced chemotolerance to doxorubicin and methotrexate, drugs routinely used for the treatment of DLBCL. Similarly, activation of Hh signaling in DLBCL cell lines with recombinant Shh N-terminal peptide resulted in increased expression of BCL2 and ABCG2 associated with increased chemotolerance. Finally, functional inhibition of ABCG2 drug efflux activity with fumitremorgin C or inhibition of Hh signaling with cyclopamine-KAAD abrogated the stroma-induced chemotolerance suggesting that targeting ABCG2 and Hh signaling may have therapeutic value in overcoming chemoresistance in DLBCL.
Website Age:
30 years and 10 months (reg. 1994-08-11).
Matching Content Categories {π}
- Education
- Science
- Health & Fitness
Content Management System {π}
What CMS is nature.com built with?
Custom-built
No common CMS systems were detected on Nature.com, and no known web development framework was identified.
Traffic Estimate {π}
What is the average monthly size of nature.com audience?
π Phenomenal Traffic: 5M - 10M visitors per month
Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.
check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush
How Does Nature.com Make Money? {πΈ}
Display Ads {π―}
The website utilizes display ads within its content to generate revenue. Check the next section for further revenue estimates.
Ads are managed by yourbow.com. Particular relationships are as follows:
Direct Advertisers (10)
google.com, pmc.com, doceree.com, yourbow.com, audienciad.com, onlinemediasolutions.com, advibe.media, aps.amazon.com, getmediamx.com, onomagic.comReseller Advertisers (38)
conversantmedia.com, rubiconproject.com, pubmatic.com, appnexus.com, openx.com, smartadserver.com, lijit.com, sharethrough.com, video.unrulymedia.com, google.com, yahoo.com, triplelift.com, onetag.com, sonobi.com, contextweb.com, 33across.com, indexexchange.com, media.net, themediagrid.com, adform.com, richaudience.com, sovrn.com, improvedigital.com, freewheel.tv, smaato.com, yieldmo.com, amxrtb.com, adyoulike.com, adpone.com, criteo.com, smilewanted.com, 152media.info, e-planning.net, smartyads.com, loopme.com, opera.com, mediafuse.com, betweendigital.comHow Much Does Nature.com Make? {π°}
Display Ads {π―}
$63,100 per month
According to our algorithms, Nature.com's monthly online income from display advertising ranges from $42,042 to $115,616.
Keywords {π}
article, google, scholar, cas, cancer, abcg, lymphoma, cells, resistance, cell, expression, hedgehog, bcell, res, nature, signaling, large, diffuse, gene, leukemia, drug, dlbcl, gli, access, oncogene, protein, multidrug, pathway, breast, content, information, singh, transporter, cookies, high, tumor, stromal, regulation, pubmed, rev, patients, acute, biol, anderson, center, research, privacy, data, target, survival,
Topics {βοΈ}
nature portfolio permissions reprints pi3k/akt/gsk3/cdk pathway privacy policy atp-binding cassette g2 author information authors nature 411 nature cancer research advertising mxr/bcrp/abcp-overexpressing cells versatile tools protein bcrp/mxr/abcp/abcg2 social media research b-cell malignancies oci-ly10 cell lines wnt signalling pathways beta-trcp ubiquitin ligase real-time quantitative pcr nci/nih grant ca16672 ruela-de-sousa rr stroma-induced drug tolerance nucleotide sequence data myeloma cell resistance fludarabine-based induction therapy stroma-induced chemotolerance suggesting shh-ptc1 pathway doxorubicin-resistant thyroid cancer tumor cell survival springerlink instant access hedgehog signaling pathway atp-dependent transporters stromal cell microenvironment single binding site lymphoma tissue banks protects germinal center permissions bcrp/mxr/abcp cell-activating factor abcg2/mxr/abcp gli transcription factors dlbcl cell lines bcrp gene polymorphisms personal data regulating cell cycle multiple myeloma cells cancer drug resistance hedgehog-induced survival abcg2 gene transcription
Schema {πΊοΈ}
WebPage:
mainEntity:
headline:ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
description:Successful treatment of diffuse large B-cell lymphoma (DLBCL) is frequently hindered by the development of resistance to conventional chemotherapy resulting in disease relapse and high mortality. High expression of antiapoptotic and/or drug transporter proteins induced by oncogenic signaling pathways has been implicated in the development of chemoresistance in cancer. Previously, our studies showed that high expression of adenosine triphosphate-binding cassette drug transporter ABCG2 in DLBCL correlated inversely with disease- and failure-free survival. In this study, we have implicated activated hedgehog (Hh) signaling pathway as a key factor behind high ABCG2 expression in DLBCL through direct upregulation of ABCG2 gene transcription. We have identified a single binding site for GLI transcription factors in the ABCG2 promoter and established its functionality using luciferase reporter, site-directed mutagenesis and chromatin-immunoprecipitation assays. Furthermore, in DLBCL tumor samples, significantly high ABCG2 and GLI1 levels were found in DLBCL tumors with lymph node involvement in comparison with DLBCL tumor cells collected from pleural and/or peritoneal effusions. This suggests a role for the stromal microenvironment in maintaining high levels of ABCG2 and GLI1. Accordingly, in vitro co-culture of DLBCL cells with HS-5 stromal cells increased ABCG2 mRNA and protein levels by paracrine activation of Hh signaling. In addition to ABCG2, co-culture of DLBCL cells with HS-5 cells also resulted in increase expression of the antiapoptotic proteins BCL2, BCL-xL and BCL2A1 and in induced chemotolerance to doxorubicin and methotrexate, drugs routinely used for the treatment of DLBCL. Similarly, activation of Hh signaling in DLBCL cell lines with recombinant Shh N-terminal peptide resulted in increased expression of BCL2 and ABCG2 associated with increased chemotolerance. Finally, functional inhibition of ABCG2 drug efflux activity with fumitremorgin C or inhibition of Hh signaling with cyclopamine-KAAD abrogated the stroma-induced chemotolerance suggesting that targeting ABCG2 and Hh signaling may have therapeutic value in overcoming chemoresistance in DLBCL.
datePublished:2011-05-30T00:00:00Z
dateModified:2011-05-30T00:00:00Z
pageStart:4874
pageEnd:4886
sameAs:https://doi.org/10.1038/onc.2011.195
keywords:
B-cell lymphoma
Cancer therapeutic resistance
Cell signalling
Gene regulation
ABCG2
ATP-binding cassettes
hedgehog pathway
GLI
diffuse large B-cell lymphoma
Medicine/Public Health
general
Internal Medicine
Cell Biology
Human Genetics
Oncology
Apoptosis
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig6_HTML.jpg
isPartOf:
name:Oncogene
issn:
1476-5594
0950-9232
volumeNumber:30
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:R R Singh
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:K Kunkalla
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:C Qu
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:E Schlette
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:S S Neelapu
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:F Samaniego
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:F Vega
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
type:ScholarlyArticle
context:https://schema.org
ScholarlyArticle:
headline:ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
description:Successful treatment of diffuse large B-cell lymphoma (DLBCL) is frequently hindered by the development of resistance to conventional chemotherapy resulting in disease relapse and high mortality. High expression of antiapoptotic and/or drug transporter proteins induced by oncogenic signaling pathways has been implicated in the development of chemoresistance in cancer. Previously, our studies showed that high expression of adenosine triphosphate-binding cassette drug transporter ABCG2 in DLBCL correlated inversely with disease- and failure-free survival. In this study, we have implicated activated hedgehog (Hh) signaling pathway as a key factor behind high ABCG2 expression in DLBCL through direct upregulation of ABCG2 gene transcription. We have identified a single binding site for GLI transcription factors in the ABCG2 promoter and established its functionality using luciferase reporter, site-directed mutagenesis and chromatin-immunoprecipitation assays. Furthermore, in DLBCL tumor samples, significantly high ABCG2 and GLI1 levels were found in DLBCL tumors with lymph node involvement in comparison with DLBCL tumor cells collected from pleural and/or peritoneal effusions. This suggests a role for the stromal microenvironment in maintaining high levels of ABCG2 and GLI1. Accordingly, in vitro co-culture of DLBCL cells with HS-5 stromal cells increased ABCG2 mRNA and protein levels by paracrine activation of Hh signaling. In addition to ABCG2, co-culture of DLBCL cells with HS-5 cells also resulted in increase expression of the antiapoptotic proteins BCL2, BCL-xL and BCL2A1 and in induced chemotolerance to doxorubicin and methotrexate, drugs routinely used for the treatment of DLBCL. Similarly, activation of Hh signaling in DLBCL cell lines with recombinant Shh N-terminal peptide resulted in increased expression of BCL2 and ABCG2 associated with increased chemotolerance. Finally, functional inhibition of ABCG2 drug efflux activity with fumitremorgin C or inhibition of Hh signaling with cyclopamine-KAAD abrogated the stroma-induced chemotolerance suggesting that targeting ABCG2 and Hh signaling may have therapeutic value in overcoming chemoresistance in DLBCL.
datePublished:2011-05-30T00:00:00Z
dateModified:2011-05-30T00:00:00Z
pageStart:4874
pageEnd:4886
sameAs:https://doi.org/10.1038/onc.2011.195
keywords:
B-cell lymphoma
Cancer therapeutic resistance
Cell signalling
Gene regulation
ABCG2
ATP-binding cassettes
hedgehog pathway
GLI
diffuse large B-cell lymphoma
Medicine/Public Health
general
Internal Medicine
Cell Biology
Human Genetics
Oncology
Apoptosis
image:
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig1_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig2_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig3_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig4_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig5_HTML.jpg
https://media.springernature.com/lw1200/springer-static/image/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_Article_BFonc2011195_Fig6_HTML.jpg
isPartOf:
name:Oncogene
issn:
1476-5594
0950-9232
volumeNumber:30
type:
Periodical
PublicationVolume
publisher:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
type:Organization
author:
name:R R Singh
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
name:K Kunkalla
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:C Qu
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:E Schlette
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:S S Neelapu
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:F Samaniego
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
type:Person
name:F Vega
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
email:[email protected]
type:Person
isAccessibleForFree:
hasPart:
isAccessibleForFree:
cssSelector:.main-content
type:WebPageElement
["Periodical","PublicationVolume"]:
name:Oncogene
issn:
1476-5594
0950-9232
volumeNumber:30
Organization:
name:Nature Publishing Group UK
logo:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
type:ImageObject
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
ImageObject:
url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
name:R R Singh
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
email:[email protected]
name:K Kunkalla
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:C Qu
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:E Schlette
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:S S Neelapu
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:F Samaniego
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
name:F Vega
affiliation:
name:The University of Texas MD Anderson Cancer Center
address:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
type:PostalAddress
type:Organization
email:[email protected]
PostalAddress:
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, USA
name:Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, USA
WebPageElement:
isAccessibleForFree:
cssSelector:.main-content
External Links {π}(160)
- Monthly income for https://link.springer.com/article/10.1038/onc.2011.195?utm_source=nature&utm_medium=referral&utm_campaign=buyArticle
- How much revenue does https://doi.org/10.1182%2Fblood-2002-01-0271 bring in?
- How much does http://scholar.google.com/scholar_lookup?&title=Low%20levels%20of%20ABCG2%20expression%20in%20adult%20AML%20blast%20samples&journal=Blood&doi=10.1182%2Fblood-2002-01-0271&volume=100&pages=4594-4601&publication_year=2002&author=Abbott%2CBL&author=Colapietro%2CAM&author=Barnes%2CY&author=Marini%2CF&author=Andreeff%2CM&author=Sorrentino%2CBP bring in each month?
- How much does https://doi.org/10.1002%2Fijc.22719 pull in?
- What's the total monthly financial gain of http://scholar.google.com/scholar_lookup?&title=The%20non-Hodgkin%20lymphomas%3A%20a%20review%20of%20the%20epidemiologic%20literature&journal=Int%20J%20Cancer&doi=10.1002%2Fijc.22719&volume=120&issue=Suppl%2012&pages=1-39&publication_year=2007&author=Alexander%2CDD&author=Mink%2CPJ&author=Adami%2CHO&author=Chang%2CET&author=Cole%2CP&author=Mandel%2CJS?
- What's the total monthly financial gain of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9850061?
- What's the revenue for http://scholar.google.com/scholar_lookup?&title=A%20human%20placenta-specific%20ATP-binding%20cassette%20gene%20%28ABCP%29%20on%20chromosome%204q22%20that%20is%20involved%20in%20multidrug%20resistance&journal=Cancer%20Res&volume=58&pages=5337-5339&publication_year=1998&author=Allikmets%2CR&author=Schriml%2CLM&author=Hutchinson%2CA&author=Romano-Spica%2CV&author=Dean%2CM?
- How much revenue does https://doi.org/10.1146%2Fannurev.pharmtox.39.1.361 generate?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Biochemical%2C%20cellular%2C%20and%20pharmacological%20aspects%20of%20the%20multidrug%20transporter&journal=Annu%20Rev%20Pharmacol%20Toxicol&doi=10.1146%2Fannurev.pharmtox.39.1.361&volume=39&pages=361-398&publication_year=1999&author=Ambudkar%2CSV&author=Dey%2CS&author=Hrycyna%2CCA&author=Ramachandra%2CM&author=Pastan%2CI&author=Gottesman%2CMM produce monthly?
- How profitable is https://doi.org/10.1182%2Fblood-2006-09-047621?
- Learn about the earnings of http://scholar.google.com/scholar_lookup?&title=Members%20of%20the%20glutathione%20and%20ABC-transporter%20families%20are%20associated%20with%20clinical%20outcome%20in%20patients%20with%20diffuse%20large%20B-cell%20lymphoma&journal=Blood&doi=10.1182%2Fblood-2006-09-047621&volume=109&pages=3409-3416&publication_year=2007&author=Andreadis%2CC&author=Gimotty%2CPA&author=Wahl%2CP&author=Hammond%2CR&author=Houldsworth%2CJ&author=Schuster%2CSJ
- How much does https://doi.org/10.1182%2Fblood-2007-01-041871 pull in monthly?
- What is the earnings of http://scholar.google.com/scholar_lookup?&title=How%20I%20treat%20patients%20with%20diffuse%20large%20B-cell%20lymphoma&journal=Blood&doi=10.1182%2Fblood-2007-01-041871&volume=110&pages=29-36&publication_year=2007&author=Armitage%2CJO?
- Explore the financials of https://doi.org/10.1016%2FS0167-4781%2801%2900270-6
- What's the profit of http://scholar.google.com/scholar_lookup?&title=Promoter%20characterization%20and%20genomic%20organization%20of%20the%20human%20breast%20cancer%20resistance%20protein%20%28ATP-binding%20cassette%20transporter%20G2%29%20gene&journal=Biochim%20Biophys%20Acta&doi=10.1016%2FS0167-4781%2801%2900270-6&volume=1520&pages=234-241&publication_year=2001&author=Bailey-Dell%2CKJ&author=Hassel%2CB&author=Doyle%2CLA&author=Ross%2CDD?
- What's the income generated by https://doi.org/10.1038%2Fsj.onc.1208240 each month?
- How much does http://scholar.google.com/scholar_lookup?&title=Constitutive%20activation%20of%20the%20shh-ptc1%20pathway%20by%20a%20patched1%20mutation%20identified%20in%20BCC&journal=Oncogene&doi=10.1038%2Fsj.onc.1208240&volume=24&pages=902-915&publication_year=2005&author=Barnes%2CEA&author=Heidtman%2CKJ&author=Donoghue%2CDJ earn?
- What's the income of https://doi.org/10.1158%2F1535-7163.MCT-08-0664?
- How much income does http://scholar.google.com/scholar_lookup?&title=Dihydroorotate%20dehydrogenase%20inhibitor%20A771726%20%28leflunomide%29%20induces%20apoptosis%20and%20diminishes%20proliferation%20of%20multiple%20myeloma%20cells&journal=Mol%20Cancer%20Ther&doi=10.1158%2F1535-7163.MCT-08-0664&volume=8&pages=366-375&publication_year=2009&author=Baumann%2CP&author=Mandl-Weber%2CS&author=Volkl%2CA&author=Adam%2CC&author=Bumeder%2CI&author=Oduncu%2CF have?
- What's https://doi.org/10.1158%2F1078-0432.CCR-04-0795's gross income?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Breast%20cancer%20resistance%20protein%20and%20P-glycoprotein%20in%20149%20adult%20acute%20myeloid%20leukemias&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-04-0795&volume=10&pages=7896-7902&publication_year=2004&author=Benderra%2CZ&author=Faussat%2CAM&author=Sayada%2CL&author=Perrot%2CJY&author=Chaoui%2CD&author=Marie%2CJP generate?
- Get to know https://doi.org/10.1074%2Fjbc.M513203200's earnings
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Gli2%20is%20targeted%20for%20ubiquitination%20and%20degradation%20by%20beta-TrCP%20ubiquitin%20ligase&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M513203200&volume=281&pages=19320-19326&publication_year=2006&author=Bhatia%2CN&author=Thiyagarajan%2CS&author=Elcheva%2CI&author=Saleem%2CM&author=Dlugosz%2CA&author=Mukhtar%2CH?
- What's the total monthly financial gain of https://doi.org/10.1074%2Fjbc.M310589200?
- How much does http://scholar.google.com/scholar_lookup?&title=Transcriptional%20regulation%20of%20bcl-2%20mediated%20by%20the%20sonic%20hedgehog%20signaling%20pathway%20through%20gli-1&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M310589200&volume=279&pages=1197-1205&publication_year=2004&author=Bigelow%2CRL&author=Chari%2CNS&author=Unden%2CAB&author=Spurgers%2CKB&author=Lee%2CS&author=Roop%2CDR pull in monthly?
- Check the income stats for https://doi.org/10.4161%2Fcc.8.18.9504
- How much does http://scholar.google.com/scholar_lookup?&title=The%20ABCG2%20resistance%20network%20of%20glioblastoma&journal=Cell%20Cycle&doi=10.4161%2Fcc.8.18.9504&volume=8&pages=2936-2944&publication_year=2009&author=Bleau%2CAM&author=Huse%2CJT&author=Holland%2CEC gross monthly?
- Get to know https://doi.org/10.1002%2Fijc.20032's earnings
- How much does http://scholar.google.com/scholar_lookup?&title=ABCG2%20overexpression%20in%20colon%20cancer%20cells%20resistant%20to%20SN38%20and%20in%20irinotecan-treated%20metastases&journal=Int%20J%20Cancer&doi=10.1002%2Fijc.20032&volume=109&pages=848-854&publication_year=2004&author=Candeil%2CL&author=Gourdier%2CI&author=Peyron%2CD&author=Vezzio%2CN&author=Copois%2CV&author=Bibeau%2CF make?
- What's the monthly income of https://doi.org/10.1016%2Fj.leukres.2010.01.008?
- How much does http://scholar.google.com/scholar_lookup?&title=Fludarabine-based%20induction%20therapy%20does%20not%20overcome%20the%20negative%20effect%20of%20ABCG2%20%28BCRP%29%20over-expression%20in%20adult%20acute%20myeloid%20leukemia%20patients&journal=Leuk%20Res&doi=10.1016%2Fj.leukres.2010.01.008&volume=34&pages=942-945&publication_year=2010&author=Damiani%2CD&author=Tiribelli%2CM&author=Michelutti%2CA&author=Geromin%2CA&author=Cavallin%2CM&author=Fabbro%2CD gross monthly?
- How much profit does https://doi.org/10.1023%2FA%3A1012823120935 generate?
- What are the total earnings of http://scholar.google.com/scholar_lookup?&title=Complete%20characterization%20of%20the%20human%20ABC%20gene%20family&journal=J%20Bioenerg%20Biomembr&doi=10.1023%2FA%3A1012823120935&volume=33&pages=475-479&publication_year=2001&author=Dean%2CM&author=Allikmets%2CR?
- Get to know what's the income of https://doi.org/10.1038%2Fonc.2010.243
- How much profit is http://scholar.google.com/scholar_lookup?&title=Inhibition%20of%20GLI%2C%20but%20not%20smoothened%2C%20induces%20apoptosis%20in%20chronic%20lymphocytic%20leukemia%20cells&journal=Oncogene&doi=10.1038%2Fonc.2010.243&volume=29&pages=4885-4895&publication_year=2010&author=Desch%2CP&author=Asslaber%2CD&author=Kern%2CD&author=Schnidar%2CH&author=Mangelberger%2CD&author=Alinger%2CB making per month?
- How much does https://doi.org/10.1038%2Fnm1614 net monthly?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Essential%20role%20of%20stromally%20induced%20hedgehog%20signaling%20in%20B-cell%20malignancies&journal=Nat%20Med&doi=10.1038%2Fnm1614&volume=13&pages=944-951&publication_year=2007&author=Dierks%2CC&author=Grbic%2CJ&author=Zirlik%2CK&author=Beigi%2CR&author=Englund%2CNP&author=Guo%2CGR bring in?
- Monthly income for https://doi.org/10.1002%2Fpath.1203
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Frequent%20expression%20of%20the%20multi-drug%20resistance-associated%20protein%20BCRP%2FMXR%2FABCP%2FABCG2%20in%20human%20tumours%20detected%20by%20the%20BXP-21%20monoclonal%20antibody%20in%20paraffin-embedded%20material&journal=J%20Pathol&doi=10.1002%2Fpath.1203&volume=198&pages=213-219&publication_year=2002&author=Diestra%2CJE&author=Scheffer%2CGL&author=Catala%2CI&author=Maliepaard%2CM&author=Schellens%2CJH&author=Scheper%2CRJ have monthly?
- What's the income of https://doi.org/10.1073%2Fpnas.95.26.15665?
- Financial intake of http://scholar.google.com/scholar_lookup?&title=A%20multidrug%20resistance%20transporter%20from%20human%20MCF-7%20breast%20cancer%20cells&journal=Proc%20Natl%20Acad%20Sci%20USA&doi=10.1073%2Fpnas.95.26.15665&volume=95&pages=15665-15670&publication_year=1998&author=Doyle%2CLA&author=Yang%2CW&author=Abruzzo%2CLV&author=Krogmann%2CT&author=Gao%2CY&author=Rishi%2CAK
- How much does https://doi.org/10.1016%2Fj.ygeno.2005.12.003 bring in each month?
- How much money does http://scholar.google.com/scholar_lookup?&title=Overlapping%20and%20distinct%20transcriptional%20regulator%20properties%20of%20the%20GLI1%20and%20GLI2%20oncogenes&journal=Genomics&doi=10.1016%2Fj.ygeno.2005.12.003&volume=87&pages=616-632&publication_year=2006&author=Eichberger%2CT&author=Sander%2CV&author=Schnidar%2CH&author=Regl%2CG&author=Kasper%2CM&author=Schmid%2CC make?
- How much does https://doi.org/10.1002%2Fjcb.22676 pull in monthly?
- What's the income of http://scholar.google.com/scholar_lookup?&title=The%20increased%20expression%20of%20receptor%20activator%20of%20nuclear-kappaB%20ligand%20%28RANKL%29%20of%20multiple%20myeloma%20bone%20marrow%20stromal%20cells%20is%20inhibited%20by%20the%20bisphosphonate%20ibandronate&journal=J%20Cell%20Biochem&doi=10.1002%2Fjcb.22676&volume=111&pages=130-137&publication_year=2010&author=Fernandez%2CM&author=Pino%2CAM&author=Figueroa%2CP&author=Rodriguez%2CJP?
- Financial intake of http://scholar.google.com/scholar_lookup?&title=The%20pathogenesis%20of%20cancer%20metastasis%3A%20the%20%E2%80%98seed%20and%20soil%E2%80%99%20hypothesis%20revisited&journal=Nat%20Rev%20Cancer&volume=3&pages=453-458&publication_year=2003&author=Fidler%2CIJ
- Discover the revenue of https://doi.org/10.1056%2FNEJM199304083281404
- http://scholar.google.com/scholar_lookup?&title=Comparison%20of%20a%20standard%20regimen%20%28CHOP%29%20with%20three%20intensive%20chemotherapy%20regimens%20for%20advanced%20non-Hodgkin%27s%20lymphoma&journal=N%20Engl%20J%20Med&doi=10.1056%2FNEJM199304083281404&volume=328&pages=1002-1006&publication_year=1993&author=Fisher%2CRI&author=Gaynor%2CER&author=Dahlberg%2CS&author=Oken%2CMM&author=Grogan%2CTM&author=Mize%2CEM's revenue stream
- Learn about the earnings of https://doi.org/10.1146%2Fannurev.med.53.082901.103929
- What's the monthly income of http://scholar.google.com/scholar_lookup?&title=Mechanisms%20of%20cancer%20drug%20resistance&journal=Annu%20Rev%20Med&doi=10.1146%2Fannurev.med.53.082901.103929&volume=53&pages=615-627&publication_year=2002&author=Gottesman%2CMM?
- Monthly income for https://doi.org/10.1038%2Fnrc706
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Multidrug%20resistance%20in%20cancer%3A%20role%20of%20ATP-dependent%20transporters&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc706&volume=2&pages=48-58&publication_year=2002&author=Gottesman%2CMM&author=Fojo%2CT&author=Bates%2CSE produce monthly?
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9657134's revenue stream
- How much does http://scholar.google.com/scholar_lookup?&title=The%20bone%20marrow%20stromal%20environment%20is%20a%20major%20factor%20in%20myeloma%20cell%20resistance%20to%20dexamethasone&journal=Exp%20Hematol&volume=26&pages=597-603&publication_year=1998&author=Grigorieva%2CI&author=Thomas%2CX&author=Epstein%2CJ earn?
- What's the monthly income of https://doi.org/10.1158%2F1541-7786.MCR-08-0142?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Hedgehog-induced%20survival%20of%20B-cell%20chronic%20lymphocytic%20leukemia%20cells%20in%20a%20stromal%20cell%20microenvironment%3A%20a%20potential%20new%20therapeutic%20target&journal=Mol%20Cancer%20Res&doi=10.1158%2F1541-7786.MCR-08-0142&volume=6&pages=1928-1936&publication_year=2008&author=Hegde%2CGV&author=Peterson%2CKJ&author=Emanuel%2CK&author=Mittal%2CAK&author=Joshi%2CAD&author=Dickinson%2CJD?
- Revenue of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11559526
- What is the monthly revenue of http://scholar.google.com/scholar_lookup?&title=Acquired%20mutations%20in%20the%20MXR%2FBCRP%2FABCP%20gene%20alter%20substrate%20specificity%20in%20MXR%2FBCRP%2FABCP-overexpressing%20cells&journal=Cancer%20Res&volume=61&pages=6635-6639&publication_year=2001&author=Honjo%2CY&author=Hrycyna%2CCA&author=Yan%2CQW&author=Medina-Perez%2CWY&author=Robey%2CRW&author=van%20de%20Laar%2CA?
- What's the total monthly financial gain of https://doi.org/10.1093%2Fcarcin%2Fbgm113?
- How much does http://scholar.google.com/scholar_lookup?&title=BCRP%20gene%20polymorphisms%20are%20associated%20with%20susceptibility%20and%20survival%20of%20diffuse%20large%20B-cell%20lymphoma&journal=Carcinogenesis&doi=10.1093%2Fcarcin%2Fbgm113&volume=28&pages=1740-1744&publication_year=2007&author=Hu%2CLL&author=Wang%2CXX&author=Chen%2CX&author=Chang%2CJ&author=Li%2CC&author=Zhang%2CY earn?
- How much money does https://link.springer.com/doi/10.1007/s00277-004-0855-x generate?
- Revenue of http://scholar.google.com/scholar_lookup?&title=Assessment%20of%20biological%20prognostic%20factors%20provides%20clinically%20relevant%20information%20in%20patients%20with%20diffuse%20large%20B-cell%20lymphoma--a%20Nordic%20Lymphoma%20Group%20study&journal=Ann%20Hematol&doi=10.1007%2Fs00277-004-0855-x&volume=83&pages=414-419&publication_year=2004&author=Jerkeman%2CM&author=Anderson%2CH&author=Dictor%2CM&author=Kvaloy%2CS&author=Akerman%2CM&author=Cavallin-Stahl%2CE
- How much revenue does https://doi.org/10.1002%2Fijc.10100 bring in?
- Earnings of http://scholar.google.com/scholar_lookup?&title=Dominant-negative%20inhibition%20of%20breast%20cancer%20resistance%20protein%20as%20drug%20efflux%20pump%20through%20the%20inhibition%20of%20S-S%20dependent%20homodimerization&journal=Int%20J%20Cancer&doi=10.1002%2Fijc.10100&volume=97&pages=626-630&publication_year=2002&author=Kage%2CK&author=Tsukahara%2CS&author=Sugiyama%2CT&author=Asada%2CS&author=Ishikawa%2CE&author=Tsuruo%2CT
- What are the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12912956?
- http://scholar.google.com/scholar_lookup?&title=Expression%20and%20functional%20analyses%20of%20breast%20cancer%20resistance%20protein%20in%20lung%20cancer&journal=Clin%20Cancer%20Res&volume=9&pages=3052-3057&publication_year=2003&author=Kawabata%2CS&author=Oka%2CM&author=Soda%2CH&author=Shiozawa%2CK&author=Nakatomi%2CK&author=Tsurutani%2CJ's financial summary
- What's the total monthly financial gain of https://doi.org/10.1038%2Fmodpathol.2009.98?
- What's the income generated by http://scholar.google.com/scholar_lookup?&title=Sonic%20hedgehog%20signaling%20proteins%20and%20ATP-binding%20cassette%20G2%20are%20aberrantly%20expressed%20in%20diffuse%20large%20B-cell%20lymphoma&journal=Mod%20Pathol&doi=10.1038%2Fmodpathol.2009.98&volume=22&pages=1312-1320&publication_year=2009&author=Kim%2CJE&author=Singh%2CRR&author=Cho-Vega%2CJH&author=Drakos%2CE&author=Davuluri%2CY&author=Khokhar%2CFA each month?
- How much income is https://doi.org/10.1074%2Fjbc.M313599200 earning monthly?
- http://scholar.google.com/scholar_lookup?&title=The%20stem%20cell%20marker%20Bcrp%2FABCG2%20enhances%20hypoxic%20cell%20survival%20through%20interactions%20with%20heme&journal=J%20Biol%20Chem&doi=10.1074%2Fjbc.M313599200&volume=279&pages=24218-24225&publication_year=2004&author=Krishnamurthy%2CP&author=Ross%2CDD&author=Nakanishi%2CT&author=Bailey-Dell%2CK&author=Zhou%2CS&author=Mercer%2CKE's total income per month
- What's the income generated by https://doi.org/10.1146%2Fannurev.pharmtox.46.120604.141238 each month?
- How much cash flow does http://scholar.google.com/scholar_lookup?&title=Role%20of%20ABCG2%2FBCRP%20in%20biology%20and%20medicine&journal=Annu%20Rev%20Pharmacol%20Toxicol&doi=10.1146%2Fannurev.pharmtox.46.120604.141238&volume=46&pages=381-410&publication_year=2006&author=Krishnamurthy%2CP&author=Schuetz%2CJD have monthly?
- What's the profit of https://doi.org/10.1038%2Fleu.2008.266?
- Financial intake of http://scholar.google.com/scholar_lookup?&title=Lymphoma%20cell%20adhesion-induced%20expression%20of%20B%20cell-activating%20factor%20of%20the%20TNF%20family%20in%20bone%20marrow%20stromal%20cells%20protects%20non-Hodgkin%2Fs%20B%20lymphoma%20cells%20from%20apoptosis&journal=Leukemia&doi=10.1038%2Fleu.2008.266&volume=23&pages=170-177&publication_year=2009&author=Lwin%2CT&author=Crespo%2CLA&author=Wu%2CA&author=Dessureault%2CS&author=Shu%2CHB&author=Moscinski%2CLC
- What's the income generated by https://doi.org/10.1038%2Fnm.2112 each month?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Tumor%20cell-specific%20bioluminescence%20platform%20to%20identify%20stroma-induced%20changes%20to%20anticancer%20drug%20activity&journal=Nat%20Med&doi=10.1038%2Fnm.2112&volume=16&pages=483-489&publication_year=2010&author=McMillin%2CDW&author=Delmore%2CJ&author=Weisberg%2CE&author=Negri%2CJM&author=Geer%2CDC&author=Klippel%2CS?
- What is the earnings of http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=9892175?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Molecular%20cloning%20of%20cDNAs%20which%20are%20highly%20overexpressed%20in%20mitoxantrone-resistant%20cells%3A%20demonstration%20of%20homology%20to%20ABC%20transport%20genes&journal=Cancer%20Res&volume=59&pages=8-13&publication_year=1999&author=Miyake%2CK&author=Mickley%2CL&author=Litman%2CT&author=Zhan%2CZ&author=Robey%2CR&author=Cristensen%2CB bring in?
- How much does https://doi.org/10.1038%2Fnrc1477 gross monthly?
- Learn how profitable http://scholar.google.com/scholar_lookup?&title=Friends%20or%20foes%E2%80%94bipolar%20effects%20of%20the%20tumour%20stroma%20in%20cancer&journal=Nat%20Rev%20Cancer&doi=10.1038%2Fnrc1477&volume=4&pages=839-849&publication_year=2004&author=Mueller%2CMM&author=Fusenig%2CNE is on a monthly basis
- What's the financial intake of https://doi.org/10.1006%2Fexcr.1999.4676?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=Hedgehog%20signal%20transduction%3A%20from%20flies%20to%20vertebrates&journal=Exp%20Cell%20Res&doi=10.1006%2Fexcr.1999.4676&volume=253&pages=25-33&publication_year=1999&author=Murone%2CM&author=Rosenthal%2CA&author=de%20Sauvage%2CFJ
- Revenue of https://doi.org/10.1159%2F000086984
- Income figures for http://scholar.google.com/scholar_lookup?&title=Immunohistochemical%20expression%20of%20multidrug%20resistance%20proteins%20as%20a%20predictor%20of%20poor%20response%20to%20chemotherapy%20and%20prognosis%20in%20patients%20with%20nodal%20diffuse%20large%20B-cell%20lymphoma&journal=Oncology&doi=10.1159%2F000086984&volume=68&pages=422-431&publication_year=2005&author=Ohsawa%2CM&author=Ikura%2CY&author=Fukushima%2CH&author=Shirai%2CN&author=Sugama%2CY&author=Suekane%2CT
- https://doi.org/10.1093%2Fnar%2F23.23.4878's financial summary
- How much money does http://scholar.google.com/scholar_lookup?&title=MatInd%20and%20MatInspector%3A%20new%20fast%20and%20versatile%20tools%20for%20detection%20of%20consensus%20matches%20in%20nucleotide%20sequence%20data&journal=Nucleic%20Acids%20Res&doi=10.1093%2Fnar%2F23.23.4878&volume=23&pages=4878-4884&publication_year=1995&author=Quandt%2CK&author=Frech%2CK&author=Karas%2CH&author=Wingender%2CE&author=Werner%2CT generate?
- https://doi.org/10.1038%2Fonc.2010.375's financial summary
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Hedgehog%20signaling%20maintains%20chemoresistance%20in%20myeloid%20leukemic%20cells&journal=Oncogene&doi=10.1038%2Fonc.2010.375&volume=29&pages=6314-6322&publication_year=2010&author=Queiroz%2CKC&author=Ruela-de-Sousa%2CRR&author=Fuhler%2CGM&author=Aberson%2CHL&author=Ferreira%2CCV&author=Peppelenbosch%2CMP
- How much does http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10646850 earn?
- How much revenue does http://scholar.google.com/scholar_lookup?&title=Fumitremorgin%20C%20reverses%20multidrug%20resistance%20in%20cells%20transfected%20with%20the%20breast%20cancer%20resistance%20protein&journal=Cancer%20Res&volume=60&pages=47-50&publication_year=2000&author=Rabindran%2CSK&author=Ross%2CDD&author=Doyle%2CLA&author=Yang%2CW&author=Greenberger%2CLM produce monthly?
- What is the monthly revenue of https://doi.org/10.1038%2Fsj.bjc.6601370?
- How much profit is http://scholar.google.com/scholar_lookup?&title=Mutations%20at%20amino-acid%20482%20in%20the%20ABCG2%20gene%20affect%20substrate%20and%20antagonist%20specificity&journal=Br%20J%20Cancer&doi=10.1038%2Fsj.bjc.6601370&volume=89&pages=1971-1978&publication_year=2003&author=Robey%2CRW&author=Honjo%2CY&author=Morisaki%2CK&author=Nadjem%2CTA&author=Runge%2CS&author=Risbood%2CM making per month?
- How much does https://doi.org/10.1006%2Fbbrc.2000.2590 earn?
- Check the income stats for http://scholar.google.com/scholar_lookup?&title=The%20product%20of%20the%20ABC%20half-transporter%20gene%20ABCG2%20%28BCRP%2FMXR%2FABCP%29%20is%20expressed%20in%20the%20plasma%20membrane&journal=Biochem%20Biophys%20Res%20Commun&doi=10.1006%2Fbbrc.2000.2590&volume=271&pages=42-46&publication_year=2000&author=Rocchi%2CE&author=Khodjakov%2CA&author=Volk%2CEL&author=Yang%2CCH&author=Litman%2CT&author=Bates%2CSE
- How much does https://doi.org/10.1016%2F0145-2126%2893%2990060-X gross monthly?
- What's http://scholar.google.com/scholar_lookup?&title=Expression%20of%20P-glycoprotein%20and%20anionic%20glutathione%20S-transferase%20genes%20in%20non-Hodgkin%27s%20lymphoma&journal=Leuk%20Res&doi=10.1016%2F0145-2126%2893%2990060-X&volume=17&pages=149-156&publication_year=1993&author=Rodriguez%2CC&author=Commes%2CT&author=Robert%2CJ&author=Rossi%2CJF's gross income?
- Monthly income for https://doi.org/10.4049%2Fjimmunol.174.3.1456
- How much does http://scholar.google.com/scholar_lookup?&title=Sonic%20hedgehog%20is%20produced%20by%20follicular%20dendritic%20cells%20and%20protects%20germinal%20center%20B%20cells%20from%20apoptosis&journal=J%20Immunol&doi=10.4049%2Fjimmunol.174.3.1456&volume=174&pages=1456-1461&publication_year=2005&author=Sacedon%2CR&author=Diez%2CB&author=Nunez%2CV&author=Hernandez-Lopez%2CC&author=Gutierrez-Frias%2CC&author=Cejalvo%2CT bring in each month?
- What's the monthly money flow for https://doi.org/10.1016%2Fj.febslet.2004.03.123?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=ABCG2%E2%80%94a%20transporter%20for%20all%20seasons&journal=FEBS%20Lett&doi=10.1016%2Fj.febslet.2004.03.123&volume=567&pages=116-120&publication_year=2004&author=Sarkadi%2CB&author=Ozvegy-Laczka%2CC&author=Nemet%2CK&author=Varadi%2CA?
- Learn about the earnings of https://doi.org/10.1046%2Fj.1365-2141.2002.03550.x
- Income figures for http://scholar.google.com/scholar_lookup?&title=Expression%20of%20the%20BCRP%20gene%20%28ABCG2%2FMXR%2FABCP%29%20in%20childhood%20acute%20lymphoblastic%20leukaemia&journal=Br%20J%20Haematol&doi=10.1046%2Fj.1365-2141.2002.03550.x&volume=118&pages=147-150&publication_year=2002&author=Sauerbrey%2CA&author=Sell%2CW&author=Steinbach%2CD&author=Voigt%2CA&author=Zintl%2CF
- How much money does https://doi.org/10.1006%2Fmeth.2001.1260 make?
- How much profit does http://scholar.google.com/scholar_lookup?&title=Real-time%20quantitative%20PCR&journal=Methods&doi=10.1006%2Fmeth.2001.1260&volume=25&pages=383-385&publication_year=2001&author=Schmittgen%2CTD make?
- How much money does https://doi.org/10.1038%2Fsj.onc.1210356 generate?
- How much does http://scholar.google.com/scholar_lookup?&title=Sonic%20Hedgehog%20promotes%20multiple%20drug%20resistance%20by%20regulation%20of%20drug%20transport&journal=Oncogene&doi=10.1038%2Fsj.onc.1210356&volume=26&pages=5674-5679&publication_year=2007&author=Sims-Mourtada%2CJ&author=Izzo%2CJG&author=Ajani%2CJ&author=Chao%2CKS net monthly?
- How much revenue does https://doi.org/10.1158%2F1078-0432.CCR-06-0176 produce monthly?
- Monthly income for http://scholar.google.com/scholar_lookup?&title=Hedgehog%3A%20an%20attribute%20to%20tumor%20regrowth%20after%20chemoradiotherapy%20and%20a%20target%20to%20improve%20radiation%20response&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-06-0176&volume=12&pages=6565-6572&publication_year=2006&author=Sims-Mourtada%2CJ&author=Izzo%2CJG&author=Apisarnthanarax%2CS&author=Wu%2CTT&author=Malhotra%2CU&author=Luthra%2CR
- How much money does https://doi.org/10.1158%2F0008-5472.CAN-08-1808 make?
- What's the financial intake of http://scholar.google.com/scholar_lookup?&title=Sonic%20hedgehog%20signaling%20pathway%20is%20activated%20in%20ALK-positive%20anaplastic%20large%20cell%20lymphoma&journal=Cancer%20Res&doi=10.1158%2F0008-5472.CAN-08-1808&volume=69&pages=2550-2558&publication_year=2009&author=Singh%2CRR&author=Cho-Vega%2CJH&author=Davuluri%2CY&author=Ma%2CS&author=Kasbidi%2CF&author=Milito%2CC?
- https://doi.org/10.1038%2Fleu.2010.35's revenue stream
- Explore the financials of http://scholar.google.com/scholar_lookup?&title=Hedgehog%20signaling%20pathway%20is%20activated%20in%20diffuse%20large%20B-cell%20lymphoma%20and%20contributes%20to%20tumor%20cell%20survival%20and%20proliferation&journal=Leukemia&doi=10.1038%2Fleu.2010.35&volume=24&pages=1025-1036&publication_year=2010&author=Singh%2CRR&author=Kim%2CJE&author=Davuluri%2CY&author=Drakos%2CE&author=Cho-Vega%2CJH&author=Amin%2CHM
- How much income is https://doi.org/10.1038%2Fsj.leu.2403168 earning monthly?
- What's the monthly money flow for http://scholar.google.com/scholar_lookup?&title=Multidrug%20resistance%20genes%20in%20infant%20acute%20lymphoblastic%20leukemia%3A%20Ara-C%20is%20not%20a%20substrate%20for%20the%20breast%20cancer%20resistance%20protein&journal=Leukemia&doi=10.1038%2Fsj.leu.2403168&volume=18&pages=78-83&publication_year=2004&author=Stam%2CRW&author=van%20den%20Heuvel-Eibrink%2CMM&author=den%20Boer%2CML&author=Ebus%2CME&author=Janka-Schaub%2CGE&author=Allen%2CJD?
- What's the profit of https://doi.org/10.1038%2Fsj.leu.2402541?
- How much does http://scholar.google.com/scholar_lookup?&title=BCRP%20gene%20expression%20is%20associated%20with%20a%20poor%20response%20to%20remission%20induction%20therapy%20in%20childhood%20acute%20myeloid%20leukemia&journal=Leukemia&doi=10.1038%2Fsj.leu.2402541&volume=16&pages=1443-1447&publication_year=2002&author=Steinbach%2CD&author=Sell%2CW&author=Voigt%2CA&author=Hermann%2CJ&author=Zintl%2CF&author=Sauerbrey%2CA bring in each month?
- What's the monthly money flow for https://doi.org/10.1038%2F35077219?
- Revenue of http://scholar.google.com/scholar_lookup?&title=The%20Hedgehog%20and%20Wnt%20signalling%20pathways%20in%20cancer&journal=Nature&doi=10.1038%2F35077219&volume=411&pages=349-354&publication_year=2001&author=Taipale%2CJ&author=Beachy%2CPA
- Find out how much https://doi.org/10.1128%2FMCB.00650-06 earns monthly
- What's the financial outcome of http://scholar.google.com/scholar_lookup?&title=Aberrant%20promoter%20methylation%20of%20the%20ABCG2%20gene%20in%20renal%20carcinoma&journal=Mol%20Cell%20Biol&doi=10.1128%2FMCB.00650-06&volume=26&pages=8572-8585&publication_year=2006&author=To%2CKK&author=Zhan%2CZ&author=Bates%2CSE?
- How much does https://doi.org/10.1159%2F000106787 make?
- How profitable is http://scholar.google.com/scholar_lookup?&title=ABCG2%20expression%20is%20an%20independent%20unfavorable%20prognostic%20factor%20in%20esophageal%20squamous%20cell%20carcinoma&journal=Oncology&doi=10.1159%2F000106787&volume=71&pages=251-258&publication_year=2006&author=Tsunoda%2CS&author=Okumura%2CT&author=Ito%2CT&author=Kondo%2CK&author=Ortiz%2CC&author=Tanaka%2CE?
- Financial intake of https://doi.org/10.1016%2Fj.leukres.2004.06.004
- Monthly income for http://scholar.google.com/scholar_lookup?&title=BCRP%20mRNA%20expression%20v.%20clinical%20outcome%20in%2040%20adult%20AML%20patients&journal=Leuk%20Res&doi=10.1016%2Fj.leukres.2004.06.004&volume=29&pages=141-146&publication_year=2005&author=Uggla%2CB&author=Stahl%2CE&author=Wagsater%2CD&author=Paul%2CC&author=Karlsson%2CMG&author=Sirsjo%2CA
- Learn how profitable https://link.springer.com/doi/10.1186/1471-2199-11-2 is on a monthly basis
- Get to know http://scholar.google.com/scholar_lookup?&title=Non-consensus%20GLI%20binding%20sites%20in%20Hedgehog%20target%20gene%20regulation&journal=BMC%20Mol%20Biol&doi=10.1186%2F1471-2199-11-2&volume=11&publication_year=2010&author=Winklmayr%2CM&author=Schmid%2CC&author=Laner-Plamberger%2CS&author=Kaser%2CA&author=Aberger%2CF&author=Eichberger%2CT's earnings
- How much profit does https://link.springer.com/doi/10.1007/s11033-008-9395-0 make?
- How profitable is http://scholar.google.com/scholar_lookup?&title=Response%20of%20the%20ABCG2%20promoter%20in%20T47D%20cells%20and%20BeWo%20cells%20to%20sex%20hormone%20treatment&journal=Mol%20Biol%20Rep&doi=10.1007%2Fs11033-008-9395-0&volume=36&pages=1889-1896&publication_year=2009&author=Yasuda%2CS&author=Kobayashi%2CM&author=Itagaki%2CS&author=Hirano%2CT&author=Iseki%2CK?
- https://doi.org/10.1158%2F1078-0432.CCR-0937-3 income
- Profit of http://scholar.google.com/scholar_lookup?&title=Breast%20cancer%20resistance%20protein%20impacts%20clinical%20outcome%20in%20platinum-based%20chemotherapy%20for%20advanced%20non-small%20cell%20lung%20cancer&journal=Clin%20Cancer%20Res&doi=10.1158%2F1078-0432.CCR-0937-3&volume=10&pages=1691-1697&publication_year=2004&author=Yoh%2CK&author=Ishii%2CG&author=Yokose%2CT&author=Minegishi%2CY&author=Tsuta%2CK&author=Goto%2CK
- How much does https://doi.org/10.1200%2FJCO.1994.12.11.2453 make?
- How much does http://scholar.google.com/scholar_lookup?&title=Multidrug%20resistance%20in%20lymphomas&journal=J%20Clin%20Oncol&doi=10.1200%2FJCO.1994.12.11.2453&volume=12&pages=2453-2459&publication_year=1994&author=Yuen%2CAR&author=Sikic%2CBI gross monthly?
- Check the income stats for https://citation-needed.springer.com/v2/references/10.1038/onc.2011.195?format=refman&flavour=references
- Revenue of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=R%20R%20Singh
- Revenue of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22R%20R%20Singh%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=K%20Kunkalla net monthly?
- How much does https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22K%20Kunkalla%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en pull in?
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=C%20Qu generate monthly?
- Get to know https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22C%20Qu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en's earnings
- How much does https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=E%20Schlette rake in every month?
- See how much https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22E%20Schlette%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en makes per month
- Explore the financials of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=S%20S%20Neelapu
- What's the financial gain of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22S%20S%20Neelapu%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- Income figures for https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=F%20Samaniego
- What's the revenue for https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22F%20Samaniego%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- What's the financial intake of https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=F%20Vega?
- What's the income of https://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22F%20Vega%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en?
- How much does https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_BFonc2011195_MOESM2_ESM.doc gross monthly?
- What is the monthly revenue of https://static-content.springer.com/esm/art%3A10.1038%2Fonc.2011.195/MediaObjects/41388_2011_BFonc2011195_MOESM3_ESM.ppt?
- What's the monthly income of https://s100.copyright.com/AppDispatchServlet?title=ABCG2%20is%20a%20direct%20transcriptional%20target%20of%20hedgehog%20signaling%20and%20involved%20in%20stroma-induced%20drug%20tolerance%20in%20diffuse%20large%20B-cell%20lymphoma&author=R%20R%20Singh%20et%20al&contentID=10.1038%2Fonc.2011.195©right=Macmillan%20Publishers%20Limited&publication=0950-9232&publicationDate=2011-05-30&publisherName=SpringerNature&orderBeanReset=true?
- How much does https://citation-needed.springer.com/v2/references/10.1038/onc.2011.195?format=refman&flavour=citation generate monthly?
- How much does https://doi.org/10.1007/s10863-023-09986-3 net monthly?
- Profit of https://doi.org/10.1038/s41374-021-00702-6
- Learn about the earnings of https://doi.org/10.1007/s00432-021-03897-9
- Learn about the earnings of https://doi.org/10.1038/s41419-021-03504-2
- Earnings of https://doi.org/10.1007/s00018-021-03901-y
- How much does https://www.protocols.io/ pull in?
- See how much https://www.natureindex.com/ makes per month
- Get to know what's the income of http://www.naturechina.com
- Monthly income for https://www.natureasia.com/ja-jp
Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Prism.js
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- mxa-002c5801.gslb.pphosted.com
- mxb-002c5801.gslb.pphosted.com
Name Servers:
- pdns1.ultradns.net
- pdns2.ultradns.net
- pdns3.ultradns.org
- pdns4.ultradns.org
- pdns5.ultradns.info
- pdns6.ultradns.co.uk
CDN Services {π¦}
- Crossref